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Q8BUR4

- DOCK1_MOUSE

UniProt

Q8BUR4 - DOCK1_MOUSE

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Protein

Dedicator of cytokinesis protein 1

Gene

Dock1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (By similarity).By similarity

GO - Molecular functioni

  1. guanyl-nucleotide exchange factor activity Source: UniProtKB-KW

GO - Biological processi

  1. apoptotic process Source: UniProtKB-KW
  2. cell migration Source: MGI
  3. hematopoietic progenitor cell differentiation Source: MGI
  4. phagocytosis Source: UniProtKB-KW
  5. small GTPase mediated signal transduction Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Guanine-nucleotide releasing factor

Keywords - Biological processi

Apoptosis, Phagocytosis

Enzyme and pathway databases

ReactomeiREACT_198374. Regulation of actin dynamics for phagocytic cup formation.
REACT_198649. Factors involved in megakaryocyte development and platelet production.
REACT_248291. DCC mediated attractive signaling.
REACT_257088. VEGFA-VEGFR2 Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Dedicator of cytokinesis protein 1
Alternative name(s):
180 kDa protein downstream of CRK
Short name:
DOCK180
Gene namesi
Name:Dock1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:2429765. Dock1.

Subcellular locationi

Cytoplasm By similarity. Membrane By similarity
Note: Recruited to membranes via its interaction with phosphatidylinositol 3,4,5-trisphosphate.By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
  2. membrane Source: UniProtKB-KW
  3. nucleus Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 18651865Dedicator of cytokinesis protein 1PRO_0000189985Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1756 – 17561Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ8BUR4.
PaxDbiQ8BUR4.
PRIDEiQ8BUR4.

PTM databases

PhosphoSiteiQ8BUR4.

Expressioni

Gene expression databases

BgeeiQ8BUR4.
CleanExiMM_DOCK1.
GenevestigatoriQ8BUR4.

Interactioni

Subunit structurei

Interacts with the SH3 domains of CRK and NCK2 via multiple sites. Interacts with nucleotide-free RAC1 via its DHR-2 domain. Interacts with ELMO1, ELMO2 and probably ELMO3 via its SH3 domain. Interacts with RAC1 (By similarity). Interacts with ELMO1 and BAI1.By similarity1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
Elmo1Q8BPU7-113EBI-646023,EBI-644162
Elmo3Q8BYZ74EBI-646023,EBI-646035
Zhx2Q8C0C03EBI-646023,EBI-646042

Protein-protein interaction databases

IntActiQ8BUR4. 7 interactions.
MINTiMINT-4093373.
STRINGi10090.ENSMUSP00000081531.

Structurei

Secondary structure

1
1865
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi14 – 163Combined sources
Beta strandi18 – 203Combined sources
Beta strandi24 – 274Combined sources
Beta strandi34 – 4411Combined sources
Beta strandi46 – 527Combined sources
Beta strandi58 – 603Combined sources
Helixi62 – 643Combined sources
Beta strandi65 – 673Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2M0YNMR-A1-74[»]
ProteinModelPortaliQ8BUR4.
SMRiQ8BUR4. Positions 1-168, 425-611, 1192-1617.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini9 – 7062SH3PROSITE-ProRule annotationAdd
BLAST
Domaini425 – 609185DHR-1Add
BLAST
Domaini1207 – 1617411DHR-2Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1687 – 16959Phosphoinositide-bindingSequence Analysis
Regioni1793 – 181927Interaction with NCK2 second and third SH3 domain (minor)By similarityAdd
BLAST
Regioni1820 – 183617Interaction with NCK2 third SH3 domain (major)By similarityAdd
BLAST
Regioni1837 – 185216Interaction with NCK2 (minor)By similarityAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi1799 – 18057SH3-binding; interaction with CRKSequence Analysis
Motifi1838 – 18436SH3-binding; interaction with CRKSequence Analysis

Domaini

The DHR-2 domain is necessary and sufficient for the GEF activity.

Sequence similaritiesi

Belongs to the DOCK family.Curated
Contains 1 DHR-1 domain.Curated
Contains 1 DHR-2 domain.Curated
Contains 1 SH3 domain.PROSITE-ProRule annotation

Keywords - Domaini

SH3 domain, SH3-binding

Phylogenomic databases

eggNOGiNOG289808.
GeneTreeiENSGT00610000085806.
HOVERGENiHBG051389.
InParanoidiQ8BUR4.
KOiK13708.
OMAiNYVVKWS.
OrthoDBiEOG7QNVK8.
PhylomeDBiQ8BUR4.
TreeFamiTF300423.

Family and domain databases

InterProiIPR016024. ARM-type_fold.
IPR027007. DHR-1_domain.
IPR027357. DHR-2.
IPR026791. DOCK.
IPR010703. DOCK_C.
IPR001452. SH3_domain.
[Graphical view]
PANTHERiPTHR23317. PTHR23317. 1 hit.
PfamiPF06920. Ded_cyto. 1 hit.
PF14429. DOCK-C2. 1 hit.
PF14604. SH3_9. 1 hit.
[Graphical view]
SMARTiSM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 4 hits.
SSF50044. SSF50044. 1 hit.
PROSITEiPS51650. DHR_1. 1 hit.
PS51651. DHR_2. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q8BUR4-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MTRWVPTKRE EKYGVAFYNY DARGADELSL QIGDTVHILE TYEGWYRGYT
60 70 80 90 100
LRKKSKKGIF PASYIHLKEA IVEGKGQHET VIPGDLPLIQ EVTTTLREWS
110 120 130 140 150
TIWRQLYVQD NREMFRSVRH MIYDLIEWRS QILSGTLPQD ELKELKKKVT
160 170 180 190 200
AKIDYGNRIL DLDLVVRDED GNILDPELTS TISLFRAHEV ASKQVEERLQ
210 220 230 240 250
EEKSQKQNMD INRQAKFAAT PSLALFVNLK NVVCKIGEDA EVLMSLYDPM
260 270 280 290 300
ESKFISENYL VRWSSSGLPK DIDRLHNLRA VFTDLGSKDL KREKISFVCQ
310 320 330 340 350
IVRVGRMELR DSNTRKLTSG LRRPFGVAVM DVTDIINGKV DDEDKQHFIP
360 370 380 390 400
FQAVAGENDF LQTVINKVIA AKEVNHKGQG LWVTLKLLPG DIHQIRKEFP
410 420 430 440 450
HLVDRTTAVA RKTGFPEIIM PGDVRNDIYV TLVQGDFDKG SKTTAKNVEV
460 470 480 490 500
TVSVYDEDGK RLEHVIFPGA GDEAISEYKS VIYYQVKQPR WFETLKVAIP
510 520 530 540 550
IEDVNRSHLR FTFRHRSSQD SKDKSEKIFA LAFVKLMRYD GTTLRDGEHD
560 570 580 590 600
LIVYKAEAKK LEDAATYLSL PSTKGELEEK GHSATGKGMQ SLGSCTISKD
610 620 630 640 650
SFQISTLVCS TKLTQNVDLL GLLKWRSNTN LLQQNLRQLM KVDGGEVVKF
660 670 680 690 700
LQDTLDALFN IMMENSESET FDTLVFDALV FIIGLIADRK FQHFNPVLET
710 720 730 740 750
YIKKHFSATL AYTKLTKVLR TYVASAEKPG VNEQLYKAIK ALEYIFKFIV
760 770 780 790 800
RSRVLFNQLY ENKGEADFVE SLLQLFRSIN DMMSSLSELT VRVKGAALKY
810 820 830 840 850
LPTIVNDVKL VFDPKELSKM FTEFILNVPA GLLTVQKLSC LIEIVHSDLF
860 870 880 890 900
TQHDCREILL PMMTDQLKYH LERQEELEAC CQLLSNILEV LYRKDVGPTQ
910 920 930 940 950
RHVQIIMETL LRTVNRTVIS MGRDSELIGN FVACMTAILR QMEDYHYAHL
960 970 980 990 1000
IKTFGKMRTD VVDFLMETFI MFKNLIGKNV YPFDWVIMNT MQNKVFLRAI
1010 1020 1030 1040 1050
NQYADMLNKR FLDQANFELQ LWNNYFHLAV AFLTQESLQL ENFSSAKRAK
1060 1070 1080 1090 1100
ILNKYGDMRR QIGFEIRDMW YNLGQHKIKF IPEMVGPILE MTLIPETELR
1110 1120 1130 1140 1150
KATLPIFFDM MQCEFHSTRS FQMFENEIIT KLDHEVEGGR GDEQYKVLFD
1160 1170 1180 1190 1200
KILLEHCRKH KYLAKTGETF VKLVVRLMER LLDYRTIMHD ENKDNRMSCT
1210 1220 1230 1240 1250
VNVLNFYKEI EREEMYIRYL YKLCDLHKEC DNYTEAAYTL LLHAKLLKWS
1260 1270 1280 1290 1300
EDVCAAHLTQ RDGFQATTQG QLKEQLYQEI IHYFDKGKMW EEAIALGKEL
1310 1320 1330 1340 1350
AEQYETEMFD YEQLSELLKK QAQFYENIVK VIRPKPDYFA VGYYGQGFPS
1360 1370 1380 1390 1400
FLRGKVFIYR GKEYERREDF EARLLTQFPN AEKMKTTSPP GDDIKTSPGQ
1410 1420 1430 1440 1450
YIQCFTVKPK LDLPPRFHRP VSEQIVSFYR VNEVQRFEYS RPIRKGEKNP
1460 1470 1480 1490 1500
DNEFANMWIE RTIYTTAYKL PGILRWFEVK SVFMVEISPL ENAIETMQLT
1510 1520 1530 1540 1550
NDKISSMVQQ HLDDPGLPIN PLSMLLNGIV DPAVMGGFAN YEKAFFTDRY
1560 1570 1580 1590 1600
LQEHPEAHGQ IEKLKDLIAW QIPFLAEGIR IHGDKVTEAL RPFHERMEAC
1610 1620 1630 1640 1650
FKQLKEKVEK QYGVRTMPSG LDDRRGSRPR SMVRSFTMPS SSRPLSVASV
1660 1670 1680 1690 1700
SSFSSDSTPS RPGSDGFALE PLLPKKMHSR SQDKLDKDDP DKEKKDKKKE
1710 1720 1730 1740 1750
KRNSKHQEIF DKEFKPADSS LQQSEAVILS ETISPLRPQR PKSQVINVIG
1760 1770 1780 1790 1800
NERRFSVSPA SPSSQQTPPP VTPRAKLSFS IQPSLELNGM MGMDVADVPP
1810 1820 1830 1840 1850
PLPLKGNMAD YGNLMENQDM MVSPTSPPPP PPQRQQPPPL PSKTPPPPPP
1860
KTTRKQTSVD SGIVQ
Length:1,865
Mass (Da):215,085
Last modified:January 9, 2007 - v3
Checksum:i4FFEAA4CBED8DE62
GO
Isoform 2 (identifier: Q8BUR4-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1572-1572: I → V
     1573-1865: Missing.

Note: No experimental confirmation available.

Show »
Length:1,572
Mass (Da):182,628
Checksum:i11CB0C8127A7573F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti1358 – 13581I → V in BAE22333. (PubMed:19468303)Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1572 – 15721I → V in isoform 2. 1 PublicationVSP_022205
Alternative sequencei1573 – 1865293Missing in isoform 2. 1 PublicationVSP_022206Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC100208 Genomic DNA. No translation available.
AC127574 Genomic DNA. No translation available.
AC129300 Genomic DNA. No translation available.
AC136515 Genomic DNA. No translation available.
AC136641 Genomic DNA. No translation available.
AK078899 mRNA. Translation: BAC37448.1.
AK082835 mRNA. Translation: BAC38645.1.
AK134905 mRNA. Translation: BAE22333.1.
AK141224 mRNA. Translation: BAE24599.1.
BC006755 mRNA. Translation: AAH06755.1.
BC009668 mRNA. Translation: AAH09668.1.
BC058998 mRNA. Translation: AAH58998.1.
BC098214 mRNA. Translation: AAH98214.1.
CCDSiCCDS40166.1. [Q8BUR4-1]
RefSeqiNP_001028592.1. NM_001033420.2. [Q8BUR4-1]
UniGeneiMm.436572.

Genome annotation databases

EnsembliENSMUST00000084488; ENSMUSP00000081531; ENSMUSG00000058325. [Q8BUR4-1]
GeneIDi330662.
KEGGimmu:330662.
UCSCiuc009kdu.1. mouse. [Q8BUR4-2]
uc009kdv.1. mouse. [Q8BUR4-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC100208 Genomic DNA. No translation available.
AC127574 Genomic DNA. No translation available.
AC129300 Genomic DNA. No translation available.
AC136515 Genomic DNA. No translation available.
AC136641 Genomic DNA. No translation available.
AK078899 mRNA. Translation: BAC37448.1 .
AK082835 mRNA. Translation: BAC38645.1 .
AK134905 mRNA. Translation: BAE22333.1 .
AK141224 mRNA. Translation: BAE24599.1 .
BC006755 mRNA. Translation: AAH06755.1 .
BC009668 mRNA. Translation: AAH09668.1 .
BC058998 mRNA. Translation: AAH58998.1 .
BC098214 mRNA. Translation: AAH98214.1 .
CCDSi CCDS40166.1. [Q8BUR4-1 ]
RefSeqi NP_001028592.1. NM_001033420.2. [Q8BUR4-1 ]
UniGenei Mm.436572.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2M0Y NMR - A 1-74 [» ]
ProteinModelPortali Q8BUR4.
SMRi Q8BUR4. Positions 1-168, 425-611, 1192-1617.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q8BUR4. 7 interactions.
MINTi MINT-4093373.
STRINGi 10090.ENSMUSP00000081531.

PTM databases

PhosphoSitei Q8BUR4.

Proteomic databases

MaxQBi Q8BUR4.
PaxDbi Q8BUR4.
PRIDEi Q8BUR4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000084488 ; ENSMUSP00000081531 ; ENSMUSG00000058325 . [Q8BUR4-1 ]
GeneIDi 330662.
KEGGi mmu:330662.
UCSCi uc009kdu.1. mouse. [Q8BUR4-2 ]
uc009kdv.1. mouse. [Q8BUR4-1 ]

Organism-specific databases

CTDi 1793.
MGIi MGI:2429765. Dock1.

Phylogenomic databases

eggNOGi NOG289808.
GeneTreei ENSGT00610000085806.
HOVERGENi HBG051389.
InParanoidi Q8BUR4.
KOi K13708.
OMAi NYVVKWS.
OrthoDBi EOG7QNVK8.
PhylomeDBi Q8BUR4.
TreeFami TF300423.

Enzyme and pathway databases

Reactomei REACT_198374. Regulation of actin dynamics for phagocytic cup formation.
REACT_198649. Factors involved in megakaryocyte development and platelet production.
REACT_248291. DCC mediated attractive signaling.
REACT_257088. VEGFA-VEGFR2 Pathway.

Miscellaneous databases

ChiTaRSi Dock1. mouse.
NextBioi 399497.
PROi Q8BUR4.
SOURCEi Search...

Gene expression databases

Bgeei Q8BUR4.
CleanExi MM_DOCK1.
Genevestigatori Q8BUR4.

Family and domain databases

InterProi IPR016024. ARM-type_fold.
IPR027007. DHR-1_domain.
IPR027357. DHR-2.
IPR026791. DOCK.
IPR010703. DOCK_C.
IPR001452. SH3_domain.
[Graphical view ]
PANTHERi PTHR23317. PTHR23317. 1 hit.
Pfami PF06920. Ded_cyto. 1 hit.
PF14429. DOCK-C2. 1 hit.
PF14604. SH3_9. 1 hit.
[Graphical view ]
SMARTi SM00326. SH3. 1 hit.
[Graphical view ]
SUPFAMi SSF48371. SSF48371. 4 hits.
SSF50044. SSF50044. 1 hit.
PROSITEi PS51650. DHR_1. 1 hit.
PS51651. DHR_2. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-289 AND 1763-1865 (ISOFORM 1), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1171-1865 (ISOFORM 2).
    Strain: C57BL/6J.
    Tissue: Olfactory bulb.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 902-1865 (ISOFORM 1).
    Strain: C57BL/6.
    Tissue: Brain, Eye and Mammary tumor.
  4. "Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex."
    Kiyokawa E., Hashimoto Y., Kurata T., Sugimura H., Matsuda M.
    J. Biol. Chem. 273:24479-24484(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION.
  5. "BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module."
    Park D., Tosello-Trampont A.-C., Elliott M.R., Lu M., Haney L.B., Ma Z., Klibanov A.L., Mandell J.W., Ravichandran K.S.
    Nature 450:430-434(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH BAI1 AND DOCK1.

Entry informationi

Entry nameiDOCK1_MOUSE
AccessioniPrimary (citable) accession number: Q8BUR4
Secondary accession number(s): Q3URT8
, Q3UY80, Q4QQL8, Q6PD14, Q8BVC9, Q91Z55, Q922V1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 3, 2003
Last sequence update: January 9, 2007
Last modified: November 26, 2014
This is version 121 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3