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Q8BU88

- RM22_MOUSE

UniProt

Q8BU88 - RM22_MOUSE

Protein

39S ribosomal protein L22, mitochondrial

Gene

Mrpl22

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: InterPro

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    39S ribosomal protein L22, mitochondrial
    Short name:
    L22mt
    Short name:
    MRP-L22
    Gene namesi
    Name:Mrpl22
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 11

    Organism-specific databases

    MGIiMGI:1333794. Mrpl22.

    Subcellular locationi

    Mitochondrion By similarity

    GO - Cellular componenti

    1. large ribosomal subunit Source: InterPro
    2. mitochondrion Source: UniProtKB

    Keywords - Cellular componenti

    Mitochondrion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transit peptidei1 – 4040MitochondrionBy similarityAdd
    BLAST
    Chaini41 – 20616639S ribosomal protein L22, mitochondrialPRO_0000261645Add
    BLAST

    Proteomic databases

    MaxQBiQ8BU88.
    PaxDbiQ8BU88.
    PRIDEiQ8BU88.

    PTM databases

    PhosphoSiteiQ8BU88.

    Expressioni

    Gene expression databases

    BgeeiQ8BU88.
    CleanExiMM_MRPL22.
    GenevestigatoriQ8BU88.

    Interactioni

    Protein-protein interaction databases

    BioGridi229782. 5 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8BU88.
    SMRiQ8BU88. Positions 72-174.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L22P family.Curated

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    eggNOGiCOG0091.
    GeneTreeiENSGT00390000002110.
    HOGENOMiHOG000048027.
    HOVERGENiHBG093486.
    InParanoidiQ8BU88.
    KOiK02890.
    OMAiNRIVYPP.
    OrthoDBiEOG79CZ0R.
    PhylomeDBiQ8BU88.
    TreeFamiTF315111.

    Family and domain databases

    Gene3Di3.90.470.10. 1 hit.
    InterProiIPR001063. Ribosomal_L22.
    IPR005727. Ribosomal_L22_bac/chlpt-type.
    [Graphical view]
    PANTHERiPTHR13501. PTHR13501. 1 hit.
    PfamiPF00237. Ribosomal_L22. 1 hit.
    [Graphical view]
    SUPFAMiSSF54843. SSF54843. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8BU88-1 [UniParc]FASTAAdd to Basket

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    MAAALLRELG ALRVPNLRIW ATQTLRVLPP SCIHTSASLD ISRKWEKKNK    50
    IVYPPQLPGE PRRPAEIYHC RRQIKYSKDK MWYLAKMIRG MSIDQALAQL 100
    EFNDKKGAQI IKEVLLEAQD MAVRDHNVEF RSNLHIAEST SGRGQCLKRI 150
    RYHGRGRFGI MEKVYCHYFV KLVEGPPPPP EVPKTAVDHA KDYIQQLRSR 200
    TIIHTL 206
    Length:206
    Mass (Da):23,805
    Last modified:March 1, 2003 - v1
    Checksum:iB7326DC02BED3390
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti198 – 1981R → P in BAC36901. (PubMed:16141072)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK077615 mRNA. Translation: BAC36901.1.
    AK086913 mRNA. Translation: BAC39761.1.
    AK164417 mRNA. Translation: BAE37779.1.
    AL928857 Genomic DNA. Translation: CAI26172.1.
    BC061191 mRNA. Translation: AAH61191.1.
    CCDSiCCDS24724.1.
    RefSeqiNP_778166.2. NM_175001.3.
    UniGeneiMm.259907.

    Genome annotation databases

    EnsembliENSMUST00000020820; ENSMUSP00000020820; ENSMUSG00000020514.
    GeneIDi216767.
    KEGGimmu:216767.
    UCSCiuc007jap.3. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK077615 mRNA. Translation: BAC36901.1 .
    AK086913 mRNA. Translation: BAC39761.1 .
    AK164417 mRNA. Translation: BAE37779.1 .
    AL928857 Genomic DNA. Translation: CAI26172.1 .
    BC061191 mRNA. Translation: AAH61191.1 .
    CCDSi CCDS24724.1.
    RefSeqi NP_778166.2. NM_175001.3.
    UniGenei Mm.259907.

    3D structure databases

    ProteinModelPortali Q8BU88.
    SMRi Q8BU88. Positions 72-174.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 229782. 5 interactions.

    PTM databases

    PhosphoSitei Q8BU88.

    Proteomic databases

    MaxQBi Q8BU88.
    PaxDbi Q8BU88.
    PRIDEi Q8BU88.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000020820 ; ENSMUSP00000020820 ; ENSMUSG00000020514 .
    GeneIDi 216767.
    KEGGi mmu:216767.
    UCSCi uc007jap.3. mouse.

    Organism-specific databases

    CTDi 29093.
    MGIi MGI:1333794. Mrpl22.

    Phylogenomic databases

    eggNOGi COG0091.
    GeneTreei ENSGT00390000002110.
    HOGENOMi HOG000048027.
    HOVERGENi HBG093486.
    InParanoidi Q8BU88.
    KOi K02890.
    OMAi NRIVYPP.
    OrthoDBi EOG79CZ0R.
    PhylomeDBi Q8BU88.
    TreeFami TF315111.

    Miscellaneous databases

    NextBioi 375302.
    PROi Q8BU88.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q8BU88.
    CleanExi MM_MRPL22.
    Genevestigatori Q8BU88.

    Family and domain databases

    Gene3Di 3.90.470.10. 1 hit.
    InterProi IPR001063. Ribosomal_L22.
    IPR005727. Ribosomal_L22_bac/chlpt-type.
    [Graphical view ]
    PANTHERi PTHR13501. PTHR13501. 1 hit.
    Pfami PF00237. Ribosomal_L22. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54843. SSF54843. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Embryo, Eye and Lung.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6J.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Testis.

    Entry informationi

    Entry nameiRM22_MOUSE
    AccessioniPrimary (citable) accession number: Q8BU88
    Secondary accession number(s): Q8BK04
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 28, 2006
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3