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Protein

39S ribosomal protein L22, mitochondrial

Gene

Mrpl22

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840. Mitochondrial translation elongation.
R-MMU-5419276. Mitochondrial translation termination.

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L22, mitochondrial
Short name:
L22mt
Short name:
MRP-L22
Gene namesi
Name:Mrpl22
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1333794. Mrpl22.

Subcellular locationi

  • Mitochondrion By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 40MitochondrionBy similarityAdd BLAST40
ChainiPRO_000026164541 – 20639S ribosomal protein L22, mitochondrialAdd BLAST166

Proteomic databases

EPDiQ8BU88.
MaxQBiQ8BU88.
PaxDbiQ8BU88.
PeptideAtlasiQ8BU88.
PRIDEiQ8BU88.

PTM databases

iPTMnetiQ8BU88.
PhosphoSitePlusiQ8BU88.

Expressioni

Gene expression databases

BgeeiENSMUSG00000020514.
CleanExiMM_MRPL22.
GenevisibleiQ8BU88. MM.

Interactioni

Subunit structurei

Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.By similarity

Protein-protein interaction databases

BioGridi229782. 1 interactor.
IntActiQ8BU88. 1 interactor.
STRINGi10090.ENSMUSP00000020820.

Structurei

3D structure databases

ProteinModelPortaliQ8BU88.
SMRiQ8BU88.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L22P family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG1711. Eukaryota.
COG0091. LUCA.
GeneTreeiENSGT00390000002110.
HOGENOMiHOG000048027.
HOVERGENiHBG093486.
InParanoidiQ8BU88.
KOiK02890.
OMAiMRSRKII.
OrthoDBiEOG091G0FH3.
PhylomeDBiQ8BU88.
TreeFamiTF315111.

Family and domain databases

CDDicd00336. Ribosomal_L22. 1 hit.
Gene3Di3.90.470.10. 1 hit.
InterProiIPR001063. Ribosomal_L22.
IPR005727. Ribosomal_L22_bac/chlpt-type.
[Graphical view]
PANTHERiPTHR13501. PTHR13501. 1 hit.
PfamiPF00237. Ribosomal_L22. 1 hit.
[Graphical view]
SUPFAMiSSF54843. SSF54843. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8BU88-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAALLRELG ALRVPNLRIW ATQTLRVLPP SCIHTSASLD ISRKWEKKNK
60 70 80 90 100
IVYPPQLPGE PRRPAEIYHC RRQIKYSKDK MWYLAKMIRG MSIDQALAQL
110 120 130 140 150
EFNDKKGAQI IKEVLLEAQD MAVRDHNVEF RSNLHIAEST SGRGQCLKRI
160 170 180 190 200
RYHGRGRFGI MEKVYCHYFV KLVEGPPPPP EVPKTAVDHA KDYIQQLRSR

TIIHTL
Length:206
Mass (Da):23,805
Last modified:March 1, 2003 - v1
Checksum:iB7326DC02BED3390
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti198R → P in BAC36901 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK077615 mRNA. Translation: BAC36901.1.
AK086913 mRNA. Translation: BAC39761.1.
AK164417 mRNA. Translation: BAE37779.1.
AL928857 Genomic DNA. Translation: CAI26172.1.
BC061191 mRNA. Translation: AAH61191.1.
CCDSiCCDS24724.1.
RefSeqiNP_778166.2. NM_175001.3.
UniGeneiMm.259907.

Genome annotation databases

EnsembliENSMUST00000020820; ENSMUSP00000020820; ENSMUSG00000020514.
GeneIDi216767.
KEGGimmu:216767.
UCSCiuc007jap.3. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK077615 mRNA. Translation: BAC36901.1.
AK086913 mRNA. Translation: BAC39761.1.
AK164417 mRNA. Translation: BAE37779.1.
AL928857 Genomic DNA. Translation: CAI26172.1.
BC061191 mRNA. Translation: AAH61191.1.
CCDSiCCDS24724.1.
RefSeqiNP_778166.2. NM_175001.3.
UniGeneiMm.259907.

3D structure databases

ProteinModelPortaliQ8BU88.
SMRiQ8BU88.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi229782. 1 interactor.
IntActiQ8BU88. 1 interactor.
STRINGi10090.ENSMUSP00000020820.

PTM databases

iPTMnetiQ8BU88.
PhosphoSitePlusiQ8BU88.

Proteomic databases

EPDiQ8BU88.
MaxQBiQ8BU88.
PaxDbiQ8BU88.
PeptideAtlasiQ8BU88.
PRIDEiQ8BU88.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000020820; ENSMUSP00000020820; ENSMUSG00000020514.
GeneIDi216767.
KEGGimmu:216767.
UCSCiuc007jap.3. mouse.

Organism-specific databases

CTDi29093.
MGIiMGI:1333794. Mrpl22.

Phylogenomic databases

eggNOGiKOG1711. Eukaryota.
COG0091. LUCA.
GeneTreeiENSGT00390000002110.
HOGENOMiHOG000048027.
HOVERGENiHBG093486.
InParanoidiQ8BU88.
KOiK02890.
OMAiMRSRKII.
OrthoDBiEOG091G0FH3.
PhylomeDBiQ8BU88.
TreeFamiTF315111.

Enzyme and pathway databases

ReactomeiR-MMU-5389840. Mitochondrial translation elongation.
R-MMU-5419276. Mitochondrial translation termination.

Miscellaneous databases

PROiQ8BU88.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020514.
CleanExiMM_MRPL22.
GenevisibleiQ8BU88. MM.

Family and domain databases

CDDicd00336. Ribosomal_L22. 1 hit.
Gene3Di3.90.470.10. 1 hit.
InterProiIPR001063. Ribosomal_L22.
IPR005727. Ribosomal_L22_bac/chlpt-type.
[Graphical view]
PANTHERiPTHR13501. PTHR13501. 1 hit.
PfamiPF00237. Ribosomal_L22. 1 hit.
[Graphical view]
SUPFAMiSSF54843. SSF54843. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRM22_MOUSE
AccessioniPrimary (citable) accession number: Q8BU88
Secondary accession number(s): Q8BK04
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: March 1, 2003
Last modified: November 30, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.