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Q8BSZ3

- Q8BSZ3_MOUSE

UniProt

Q8BSZ3 - Q8BSZ3_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Npm1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. NF-kappaB binding Source: UniProtKB
    2. protein binding Source: MGI
    3. ribosomal large subunit binding Source: MGI
    4. ribosomal small subunit binding Source: MGI
    5. RNA binding Source: MGI
    6. rRNA binding Source: MGI
    7. unfolded protein binding Source: UniProtKB

    GO - Biological processi

    1. cell aging Source: UniProtKB
    2. cell growth Source: MGI
    3. cell volume homeostasis Source: MGI
    4. centrosome cycle Source: UniProtKB
    5. negative regulation of cell proliferation Source: UniProtKB
    6. negative regulation of mRNA splicing, via spliceosome Source: MGI
    7. nucleocytoplasmic transport Source: MGI
    8. positive regulation of cell proliferation Source: MGI
    9. positive regulation of cellular biosynthetic process Source: MGI
    10. positive regulation of centrosome duplication Source: MGI
    11. positive regulation of protein kinase activity Source: MGI
    12. protein localization Source: MGI
    13. protein oligomerization Source: MGI
    14. regulation of cell cycle Source: MGI
    15. regulation of centrosome duplication Source: MGI
    16. regulation of DNA damage response, signal transduction by p53 class mediator Source: MGI
    17. ribosomal large subunit biogenesis Source: MGI
    18. ribosomal large subunit export from nucleus Source: MGI
    19. ribosomal small subunit biogenesis Source: MGI
    20. ribosomal small subunit export from nucleus Source: MGI
    21. rRNA export from nucleus Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Npm1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:106184. Npm1.

    Subcellular locationi

    GO - Cellular componenti

    1. centrosome Source: UniProtKB
    2. cytoplasm Source: UniProtKB
    3. cytosol Source: MGI
    4. granular component Source: MGI
    5. large ribosomal subunit Source: MGI
    6. nuclear speck Source: MGI
    7. nucleolus Source: MGI
    8. nucleoplasm Source: MGI
    9. nucleus Source: UniProtKB
    10. ribonucleoprotein complex Source: MGI
    11. small ribosomal subunit Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiQ8BSZ3.
    BgeeiQ8BSZ3.
    GenevestigatoriQ8BSZ3.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8BSZ3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG001860.
    InParanoidiQ8BSZ3.

    Family and domain databases

    Gene3Di2.60.120.340. 1 hit.
    InterProiIPR004301. Nucleoplasmin.
    IPR024057. Nucleoplasmin_core_dom.
    [Graphical view]
    PANTHERiPTHR22747. PTHR22747. 1 hit.
    SUPFAMiSSF69203. SSF69203. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    Q8BSZ3-1 [UniParc]FASTAAdd to Basket

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    MEDSMDMDMS PLRPQNYLFG CELKADKDYH FKVDNDENEH QLSLRTVSLG    50
    AGAKDELHIV EAEAMNYEGS PIKVTLATLK MSVQPTVSLG GFEITPPVVL 100
    RLKCGSGPVH ISGQHLVAVE EDAESEDEDE EDVKLLGMSG KRSAPGGGNK 150
    VPQKKVKLDE DDEDDDEDDE DDEDDDDDDF DEEETEEKVP VKKSVRDTPA 200
    KNAQKSNQNG KDLKPSTPRS KGQESF 226
    Length:226
    Mass (Da):24,982
    Last modified:March 1, 2003 - v1
    Checksum:i9F5306D0ACDFAEF6
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei226 – 2261Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK028370 mRNA. Translation: BAC25910.1.
    UniGeneiMm.485384.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK028370 mRNA. Translation: BAC25910.1 .
    UniGenei Mm.485384.

    3D structure databases

    ProteinModelPortali Q8BSZ3.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:106184. Npm1.

    Phylogenomic databases

    HOVERGENi HBG001860.
    InParanoidi Q8BSZ3.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8BSZ3.
    Bgeei Q8BSZ3.
    Genevestigatori Q8BSZ3.

    Family and domain databases

    Gene3Di 2.60.120.340. 1 hit.
    InterProi IPR004301. Nucleoplasmin.
    IPR024057. Nucleoplasmin_core_dom.
    [Graphical view ]
    PANTHERi PTHR22747. PTHR22747. 1 hit.
    SUPFAMi SSF69203. SSF69203. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Placenta and extra embryonic tissueImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Placenta and extra embryonic tissueImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Placenta and extra embryonic tissueImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Placenta and extra embryonic tissueImported.
    5. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Placenta and extra embryonic tissueImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Placenta and extra embryonic tissueImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Placenta and extra embryonic tissueImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Placenta and extra embryonic tissueImported.

    Entry informationi

    Entry nameiQ8BSZ3_MOUSE
    AccessioniPrimary (citable) accession number: Q8BSZ3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)