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Q8BSZ3 (Q8BSZ3_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Npm1 MGI 106184
OrganismMus musculus (Mouse) EMBL BAC25910.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length226 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Gene Ontology (GO)
   Biological_processcell aging

Inferred from sequence or structural similarity. Source: UniProtKB

cell growth

Inferred from direct assay PubMed 18809582. Source: MGI

cell volume homeostasis

Inferred from direct assay PubMed 18809582. Source: MGI

centrosome cycle

Inferred from sequence or structural similarity. Source: UniProtKB

negative regulation of cell proliferation

Inferred from sequence or structural similarity. Source: UniProtKB

negative regulation of mRNA splicing, via spliceosome

Inferred from direct assay PubMed 16376875. Source: MGI

nucleocytoplasmic transport

Inferred from direct assay PubMed 15485902. Source: MGI

positive regulation of cell proliferation

Inferred from direct assay PubMed 18809582. Source: MGI

positive regulation of cellular biosynthetic process

Inferred from direct assay PubMed 18809582. Source: MGI

positive regulation of centrosome duplication

Inferred from genetic interaction PubMed 17015463. Source: MGI

positive regulation of protein kinase activity

Inferred from direct assay PubMed 17015463. Source: MGI

protein localization

Inferred from mutant phenotype PubMed 16199867. Source: MGI

protein oligomerization

Inferred from sequence orthology PubMed 18809582. Source: MGI

rRNA export from nucleus

Inferred from direct assay PubMed 18809582. Source: MGI

regulation of DNA damage response, signal transduction by p53 class mediator

Inferred from genetic interaction PubMed 16199867. Source: MGI

regulation of cell cycle

Inferred from mutant phenotype PubMed 15485902. Source: MGI

regulation of centrosome duplication

Inferred from mutant phenotype PubMed 16007073. Source: MGI

ribosomal large subunit biogenesis

Inferred from direct assay PubMed 18809582. Source: MGI

ribosomal large subunit export from nucleus

Inferred from mutant phenotype PubMed 18809582. Source: MGI

ribosomal small subunit biogenesis

Inferred from direct assay PubMed 18809582. Source: MGI

ribosomal small subunit export from nucleus

Inferred from direct assay PubMed 18809582. Source: MGI

   Cellular_componentcentrosome

Inferred from sequence or structural similarity. Source: UniProtKB

cytoplasm

Inferred from sequence or structural similarity. Source: UniProtKB

cytosol

Inferred from direct assay PubMed 18809582. Source: MGI

granular component

Inferred from direct assay PubMed 15485902. Source: MGI

large ribosomal subunit

Inferred from direct assay PubMed 18809582. Source: MGI

nuclear speck

Inferred from direct assay PubMed 16376875. Source: MGI

nucleolus

Inferred from direct assay PubMed 10716735PubMed 12374805PubMed 15485902PubMed 15596447PubMed 15615785PubMed 15989966PubMed 16027046PubMed 16297385PubMed 16648475PubMed 16855206PubMed 18023416PubMed 18809582PubMed 2100262. Source: MGI

nucleoplasm

Inferred from direct assay PubMed 12374805PubMed 16297385PubMed 18809582. Source: MGI

nucleus

Inferred from sequence or structural similarity. Source: UniProtKB

ribonucleoprotein complex

Inferred from sequence orthology PubMed 18809582. Source: MGI

small ribosomal subunit

Inferred from direct assay PubMed 18809582. Source: MGI

   Molecular_functionNF-kappaB binding

Inferred from sequence or structural similarity. Source: UniProtKB

RNA binding

Inferred from direct assay PubMed 16376875. Source: MGI

rRNA binding

Inferred from direct assay PubMed 15596447PubMed 18809582. Source: MGI

ribosomal large subunit binding

Inferred from sequence orthology PubMed 18809582. Source: MGI

ribosomal small subunit binding

Inferred from sequence orthology PubMed 18809582. Source: MGI

unfolded protein binding

Inferred from sequence or structural similarity. Source: UniProtKB

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue2261 EMBL BAC25910.1

Sequences

Sequence LengthMass (Da)Tools
Q8BSZ3 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 9F5306D0ACDFAEF6

FASTA22624,982
        10         20         30         40         50         60 
MEDSMDMDMS PLRPQNYLFG CELKADKDYH FKVDNDENEH QLSLRTVSLG AGAKDELHIV 

        70         80         90        100        110        120 
EAEAMNYEGS PIKVTLATLK MSVQPTVSLG GFEITPPVVL RLKCGSGPVH ISGQHLVAVE 

       130        140        150        160        170        180 
EDAESEDEDE EDVKLLGMSG KRSAPGGGNK VPQKKVKLDE DDEDDDEDDE DDEDDDDDDF 

       190        200        210        220 
DEEETEEKVP VKKSVRDTPA KNAQKSNQNG KDLKPSTPRS KGQESF 

« Hide

References

[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC25910.1.
Tissue: Placenta and extra embryonic tissue EMBL BAC25910.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC25910.1.
Tissue: Placenta and extra embryonic tissue EMBL BAC25910.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC25910.1.
Tissue: Placenta and extra embryonic tissue EMBL BAC25910.1.
[4]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC25910.1.
Tissue: Placenta and extra embryonic tissue EMBL BAC25910.1.
[5]Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P., Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W., Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T., Hori F., Imotani K. expand/collapse author list , Ishii Y., Itoh M., Kagawa I., Kasukawa T., Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M., Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y., Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H., Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M., Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T., Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.
Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC25910.1.
Tissue: Placenta and extra embryonic tissue EMBL BAC25910.1.
[6]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC25910.1.
Tissue: Placenta and extra embryonic tissue EMBL BAC25910.1.
[7]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC25910.1.
Tissue: Placenta and extra embryonic tissue EMBL BAC25910.1.
[8]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC25910.1.
Tissue: Placenta and extra embryonic tissue EMBL BAC25910.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK028370 mRNA. Translation: BAC25910.1.
UniGeneMm.485384.

3D structure databases

ProteinModelPortalQ8BSZ3.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:106184. Npm1.

Phylogenomic databases

HOVERGENHBG001860.
InParanoidQ8BSZ3.

Gene expression databases

ArrayExpressQ8BSZ3.
BgeeQ8BSZ3.
GenevestigatorQ8BSZ3.

Family and domain databases

Gene3D2.60.120.340. 1 hit.
InterProIPR004301. Nucleoplasmin.
IPR024057. Nucleoplasmin_core_dom.
[Graphical view]
PANTHERPTHR22747. PTHR22747. 1 hit.
SUPFAMSSF69203. SSF69203. 1 hit.
ProtoNetSearch...

Other

SOURCESearch...

Entry information

Entry nameQ8BSZ3_MOUSE
AccessionPrimary (citable) accession number: Q8BSZ3
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: April 16, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)