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Q8BSZ3

- Q8BSZ3_MOUSE

UniProt

Q8BSZ3 - Q8BSZ3_MOUSE

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Protein
Submitted name: Putative uncharacterized protein
Gene
Npm1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. NF-kappaB binding Source: UniProtKB
  2. RNA binding Source: MGI
  3. protein binding Source: MGI
  4. rRNA binding Source: MGI
  5. ribosomal large subunit binding Source: MGI
  6. ribosomal small subunit binding Source: MGI
  7. unfolded protein binding Source: UniProtKB

GO - Biological processi

  1. cell aging Source: UniProtKB
  2. cell growth Source: MGI
  3. cell volume homeostasis Source: MGI
  4. centrosome cycle Source: UniProtKB
  5. negative regulation of cell proliferation Source: UniProtKB
  6. negative regulation of mRNA splicing, via spliceosome Source: MGI
  7. nucleocytoplasmic transport Source: MGI
  8. positive regulation of cell proliferation Source: MGI
  9. positive regulation of cellular biosynthetic process Source: MGI
  10. positive regulation of centrosome duplication Source: MGI
  11. positive regulation of protein kinase activity Source: MGI
  12. protein localization Source: MGI
  13. protein oligomerization Source: MGI
  14. rRNA export from nucleus Source: MGI
  15. regulation of DNA damage response, signal transduction by p53 class mediator Source: MGI
  16. regulation of cell cycle Source: MGI
  17. regulation of centrosome duplication Source: MGI
  18. ribosomal large subunit biogenesis Source: MGI
  19. ribosomal large subunit export from nucleus Source: MGI
  20. ribosomal small subunit biogenesis Source: MGI
  21. ribosomal small subunit export from nucleus Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Npm1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:106184. Npm1.

Subcellular locationi

GO - Cellular componenti

  1. centrosome Source: UniProtKB
  2. cytoplasm Source: UniProtKB
  3. cytosol Source: MGI
  4. granular component Source: MGI
  5. large ribosomal subunit Source: MGI
  6. nuclear speck Source: MGI
  7. nucleolus Source: MGI
  8. nucleoplasm Source: MGI
  9. nucleus Source: UniProtKB
  10. ribonucleoprotein complex Source: MGI
  11. small ribosomal subunit Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiQ8BSZ3.
BgeeiQ8BSZ3.
GenevestigatoriQ8BSZ3.

Structurei

3D structure databases

ProteinModelPortaliQ8BSZ3.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG001860.
InParanoidiQ8BSZ3.

Family and domain databases

Gene3Di2.60.120.340. 1 hit.
InterProiIPR004301. Nucleoplasmin.
IPR024057. Nucleoplasmin_core_dom.
[Graphical view]
PANTHERiPTHR22747. PTHR22747. 1 hit.
SUPFAMiSSF69203. SSF69203. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q8BSZ3-1 [UniParc]FASTAAdd to Basket

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MEDSMDMDMS PLRPQNYLFG CELKADKDYH FKVDNDENEH QLSLRTVSLG    50
AGAKDELHIV EAEAMNYEGS PIKVTLATLK MSVQPTVSLG GFEITPPVVL 100
RLKCGSGPVH ISGQHLVAVE EDAESEDEDE EDVKLLGMSG KRSAPGGGNK 150
VPQKKVKLDE DDEDDDEDDE DDEDDDDDDF DEEETEEKVP VKKSVRDTPA 200
KNAQKSNQNG KDLKPSTPRS KGQESF 226
Length:226
Mass (Da):24,982
Last modified:March 1, 2003 - v1
Checksum:i9F5306D0ACDFAEF6
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei226 – 2261Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK028370 mRNA. Translation: BAC25910.1.
UniGeneiMm.485384.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK028370 mRNA. Translation: BAC25910.1 .
UniGenei Mm.485384.

3D structure databases

ProteinModelPortali Q8BSZ3.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:106184. Npm1.

Phylogenomic databases

HOVERGENi HBG001860.
InParanoidi Q8BSZ3.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

ArrayExpressi Q8BSZ3.
Bgeei Q8BSZ3.
Genevestigatori Q8BSZ3.

Family and domain databases

Gene3Di 2.60.120.340. 1 hit.
InterProi IPR004301. Nucleoplasmin.
IPR024057. Nucleoplasmin_core_dom.
[Graphical view ]
PANTHERi PTHR22747. PTHR22747. 1 hit.
SUPFAMi SSF69203. SSF69203. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Placenta and extra embryonic tissueImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Placenta and extra embryonic tissueImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Placenta and extra embryonic tissueImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Placenta and extra embryonic tissueImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Placenta and extra embryonic tissueImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Placenta and extra embryonic tissueImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Placenta and extra embryonic tissueImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Placenta and extra embryonic tissueImported.

Entry informationi

Entry nameiQ8BSZ3_MOUSE
AccessioniPrimary (citable) accession number: Q8BSZ3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: June 11, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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