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Protein

MOB kinase activator 3A

Gene

Mob3a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

May regulate the activity of kinases.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi83ZincBy similarity1
Metal bindingi88ZincBy similarity1
Metal bindingi165ZincBy similarity1
Metal bindingi170ZincBy similarity1

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
MOB kinase activator 3A
Alternative name(s):
Mob1 homolog 2A
Mps one binder kinase activator-like 2A
Gene namesi
Name:Mob3a
Synonyms:Mobkl2a
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:3050117. Mob3a.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001935711 – 217MOB kinase activator 3AAdd BLAST217

Proteomic databases

EPDiQ8BSU7.
MaxQBiQ8BSU7.
PaxDbiQ8BSU7.
PRIDEiQ8BSU7.

PTM databases

PhosphoSitePlusiQ8BSU7.

Expressioni

Gene expression databases

BgeeiENSMUSG00000003348.
GenevisibleiQ8BSU7. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000003438.

Structurei

3D structure databases

ProteinModelPortaliQ8BSU7.
SMRiQ8BSU7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MOB1/phocein family.Curated

Phylogenomic databases

eggNOGiKOG1903. Eukaryota.
ENOG410XSM4. LUCA.
GeneTreeiENSGT00550000074456.
HOGENOMiHOG000164685.
HOVERGENiHBG052489.
InParanoidiQ8BSU7.
OMAiEHKYKKP.
OrthoDBiEOG091G0LDA.
PhylomeDBiQ8BSU7.
TreeFamiTF300789.

Family and domain databases

Gene3Di1.20.140.30. 1 hit.
InterProiView protein in InterPro
IPR005301. MOB_kinase_act_fam.
PANTHERiPTHR22599. PTHR22599. 1 hit.
PfamiView protein in Pfam
PF03637. Mob1_phocein. 1 hit.
SMARTiView protein in SMART
SM01388. Mob1_phocein. 1 hit.
SUPFAMiSSF101152. SSF101152. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8BSU7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNPFLKQVF NKDKTFRPKR KFEPGTQRFE LHKRAQASLN AGLDLRLAVQ
60 70 80 90 100
LPPGEDLNDW VAVHVVDFFN RINLIYGTIS DGCTEQSCPV MSGGPKYEYR
110 120 130 140 150
WQDEQRFRKP TALSAPRYMD LLMDWIEVQI NNEDIFPTNV GTPFPKTFLQ
160 170 180 190 200
AVRKILSRLF RVFVHVYIHH FDRIAQMGSE AHVNTCYKHF YYFVTEFNLI
210
DPKELEPLKE MTSRMCH
Length:217
Mass (Da):25,552
Last modified:March 1, 2003 - v1
Checksum:iBF8D013394E83C77
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK030481 mRNA. Translation: BAC26983.1.
AK170394 mRNA. Translation: BAE41766.1.
AK171197 mRNA. Translation: BAE42307.1.
BC058238 mRNA. Translation: AAH58238.1.
CCDSiCCDS35982.1.
RefSeqiNP_766045.2. NM_172457.2.
UniGeneiMm.49309.

Genome annotation databases

EnsembliENSMUST00000003438; ENSMUSP00000003438; ENSMUSG00000003348.
GeneIDi208228.
KEGGimmu:208228.
UCSCiuc007geh.1. mouse.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiMOB3A_MOUSE
AccessioniPrimary (citable) accession number: Q8BSU7
Secondary accession number(s): Q3TBK2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 21, 2004
Last sequence update: March 1, 2003
Last modified: June 7, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families