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Q8BSQ9

- PB1_MOUSE

UniProt

Q8BSQ9 - PB1_MOUSE

Protein

Protein polybromo-1

Gene

Pbrm1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 96 (01 Oct 2014)
      Sequence version 4 (27 Jul 2011)
      Previous versions | rss
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    Functioni

    Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi1379 – 144769HMG boxPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. chromatin binding Source: MGI
    2. DNA binding Source: UniProtKB-KW
    3. protein binding Source: UniProtKB

    GO - Biological processi

    1. blood vessel remodeling Source: DFLAT
    2. cardiac vascular smooth muscle cell development Source: DFLAT
    3. chromatin modification Source: UniProtKB-KW
    4. epicardium-derived cardiac endothelial cell differentiation Source: DFLAT
    5. heart development Source: MGI
    6. heart morphogenesis Source: DFLAT
    7. negative regulation of cell proliferation Source: UniProtKB
    8. placenta development Source: MGI
    9. positive regulation of transcription, DNA-templated Source: DFLAT
    10. transcription, DNA-templated Source: UniProtKB-KW
    11. vasculogenesis involved in coronary vascular morphogenesis Source: DFLAT

    Keywords - Molecular functioni

    Chromatin regulator

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein polybromo-1
    Alternative name(s):
    BRG1-associated factor 180
    Short name:
    BAF180
    Gene namesi
    Name:Pbrm1
    Synonyms:Baf180, Pb1
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 14

    Organism-specific databases

    MGIiMGI:1923998. Pbrm1.

    Subcellular locationi

    Nucleus PROSITE-ProRule annotation

    GO - Cellular componenti

    1. kinetochore Source: MGI
    2. nucleus Source: MGI

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Keywords - Diseasei

    Tumor suppressor

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 16341634Protein polybromo-1PRO_0000351134Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei10 – 101PhosphoserineBy similarity
    Modified residuei39 – 391PhosphoserineBy similarity
    Modified residuei131 – 1311PhosphoserineBy similarity
    Modified residuei319 – 3191PhosphoserineBy similarity
    Modified residuei353 – 3531Phosphoserine1 Publication
    Modified residuei355 – 3551Phosphoserine1 Publication
    Modified residuei371 – 3711PhosphoserineBy similarity
    Modified residuei375 – 3751PhosphoserineBy similarity
    Modified residuei414 – 4141N6-acetyllysine1 Publication
    Modified residuei498 – 4981PhosphoserineBy similarity
    Modified residuei636 – 6361PhosphoserineBy similarity
    Modified residuei648 – 6481PhosphoserineBy similarity
    Modified residuei1289 – 12891Phosphotyrosine1 Publication
    Modified residuei1405 – 14051PhosphoserineBy similarity

    Keywords - PTMi

    Acetylation, Phosphoprotein

    Proteomic databases

    MaxQBiQ8BSQ9.
    PaxDbiQ8BSQ9.
    PRIDEiQ8BSQ9.

    PTM databases

    PhosphoSiteiQ8BSQ9.

    Expressioni

    Developmental stagei

    Expressed ubiquitously throughout the developing spinal cord, brain and other embryonic tissues at E10.5-E16.5.1 Publication

    Gene expression databases

    ArrayExpressiQ8BSQ9.
    BgeeiQ8BSQ9.
    GenevestigatoriQ8BSQ9.

    Interactioni

    Subunit structurei

    Component of the SWI/SNF-B (PBAF) chromatin-remodeling complex, which contains at least SMARCA4/BRG1, SMARCB1/SNF5/INI1/BAF47, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, perhaps SMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PB1/BAF180, ARID2/BAF200, ARID1A/BAF250A or ARID1B/BAF250B and actin. Interacts with acetylated 'Lys-14' of histone H3 (H3K14ac), and may also interact with other acetylated or methylated Lys residues on histone H3 By similarity. Interacts with PHF10/BAF45A.By similarity1 Publication

    Protein-protein interaction databases

    DIPiDIP-48885N.
    IntActiQ8BSQ9. 2 interactions.
    MINTiMINT-4112204.

    Structurei

    Secondary structure

    1
    1634
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi659 – 67113
    Beta strandi675 – 6773
    Beta strandi679 – 6813
    Helixi682 – 6843
    Turni690 – 6923
    Helixi694 – 6996
    Helixi706 – 7149
    Helixi721 – 73818
    Helixi744 – 75916

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2YQDNMR-A650-762[»]
    ProteinModelPortaliQ8BSQ9.
    SMRiQ8BSQ9. Positions 43-154, 176-292, 388-494, 510-628, 651-766, 773-914, 957-1102.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ8BSQ9.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini64 – 13471Bromo 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini200 – 27071Bromo 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini400 – 47071Bromo 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini538 – 60871Bromo 4PROSITE-ProRule annotationAdd
    BLAST
    Domaini676 – 74671Bromo 5PROSITE-ProRule annotationAdd
    BLAST
    Domaini792 – 86271Bromo 6PROSITE-ProRule annotationAdd
    BLAST
    Domaini956 – 1074119BAH 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini1156 – 1272117BAH 2PROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi630 – 6334Poly-Asp
    Compositional biasi1468 – 1599132Pro-richAdd
    BLAST

    Sequence similaritiesi

    Contains 2 BAH domains.PROSITE-ProRule annotation
    Contains 6 bromo domains.PROSITE-ProRule annotation
    Contains 1 HMG box DNA-binding domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Bromodomain, Repeat

    Phylogenomic databases

    eggNOGiCOG5076.
    GeneTreeiENSGT00390000003017.
    HOVERGENiHBG079860.
    OrthoDBiEOG78H3S6.

    Family and domain databases

    Gene3Di1.10.30.10. 1 hit.
    1.20.920.10. 6 hits.
    InterProiIPR001025. BAH_dom.
    IPR001487. Bromodomain.
    IPR018359. Bromodomain_CS.
    IPR009071. HMG_box_dom.
    [Graphical view]
    PfamiPF01426. BAH. 2 hits.
    PF00439. Bromodomain. 6 hits.
    PF00505. HMG_box. 1 hit.
    [Graphical view]
    PRINTSiPR00503. BROMODOMAIN.
    SMARTiSM00439. BAH. 2 hits.
    SM00297. BROMO. 6 hits.
    SM00398. HMG. 1 hit.
    [Graphical view]
    SUPFAMiSSF47095. SSF47095. 1 hit.
    SSF47370. SSF47370. 6 hits.
    PROSITEiPS51038. BAH. 2 hits.
    PS00633. BROMODOMAIN_1. 5 hits.
    PS50014. BROMODOMAIN_2. 6 hits.
    PS50118. HMG_BOX_2. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q8BSQ9-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MGSKRRRATS PSSSVSGDFD DGHHSVPTPG PSRKRRRLSN LPTVDPIAVC     50
    HELYNTIRDY KDEQGRLLCE LFIRAPKRRN QPDYYEVVSQ PIDLMKIQQK 100
    LKMEEYDDVN LLTADFQLLF NNAKAYYKPD SPEYKAACKL WDLYLRTRNE 150
    FVQKGEADDE DDDEDGQDNQ GTLADGSSPG YLKEILEQLL EAIVVATNPS 200
    GRLISELFQK LPSKVQYPDY YAIIKEPIDL KTIAQRIQNG SYKSIHAMAK 250
    DIDLLAKNAK TYNEPGSQVF KDANSIKKIF YMKKAEIEHH EMTKSSLRIR 300
    TASNLAAARL TGPSHNKSSL GEERNPTSKY YRNKRAVQGG RLSAITMALQ 350
    YGSESEEDAA LAAARYEEGE SEAESITSFM DVSNPFHQLY DTVRSCRNHQ 400
    GQLIAEPFFH LPSKKKYPDY YQQIKMPISL QQIRTKLKNQ EYETLDHLEC 450
    DLNLMFENAK RYNVPNSAIY KRVLKLQQVM QAKKKELARR DDIEDGDSMI 500
    SSATSDTGSA KRKSKKNIRK QRMKILFNVV LEAREPGSGR RLCDLFMVKP 550
    SKKDYPDYYK IILEPMDLKI IEHNIRNDKY AGEEGMMEDM KLMFRNARHY 600
    NEEGSQVYND AHILEKLLKD KRKELGPLPD DDDMASPKLK LSRKSGVSPK 650
    KSKYMTPMQQ KLNEVYEAVK NYTDKRGRRL SAIFLRLPSR SELPDYYLTI 700
    KKPMDMEKIR SHMMANKYQD IDSMVEDFVM MFNNACTYNE PESLIYKDAL 750
    VLHKVLLETR RDLEGDEDSH VPNVTLLIQE LIHNLFVSVM SHQDDEGRCY 800
    SDSLAEIPAV DPNSPNKPPL TFDIIRKNVE SNRYRRLDLF QEHMFEVLER 850
    ARRMNRTDSE IYEDAVELQQ FFIRIRDELC KNGEILLSPA LSYTTKHLHN 900
    DVEKEKKEKL PKEIEEDKLK REEEKREAEK SEDSSGTTGL SGLHRTYSQD 950
    CSFKNSMYHV GDYVYVEPAE ANLQPHIVCI ERLWEDSAGE KWLYGCWFYR 1000
    PNETFHLATR KFLEKEVFKS DYYNKVPVSK ILGKCVVMFV KEYFKLCPEN 1050
    FRDEDVFVCE SRYSAKTKSF KKIKLWTMPI SSVRFVPRDV PLPVVRVASV 1100
    FANADKGDDE KNTDNSDDNR AEDNFNLEKE KEDVPVEMSN GEPGCHYFEQ 1150
    LRYNDMWLKV GDCVFIKSHG LVRPRVGRIE KVWVRDGAAY FYGPIFIHPE 1200
    ETEHEPTKMF YKKEVFLSNL EETCPMSCIL GKCAVLSFKD FLSCRPTEIP 1250
    ENDILLCESR YNESDKQMKK FKGLKRFSLS AKVVDDEIYY FRKPIIPQKE 1300
    PSPLLEKKIQ LLEAKFAELE GGDDDIEEMG EEDSEVIEAP SLPQLQTPLA 1350
    NELDLMPYTP PQSTPKSAKG SAKKESSKRK INMSGYILFS SEMRAVIKAQ 1400
    HPDYSFGELS RLVGTEWRNL ETAKKAEYEG MMGGYPPGLP PLQGPVDGLV 1450
    SMGSMQPLHP GGPPPHHLPP GVPGLPGIPP PGVMNQGVAP MVGTPAPGGS 1500
    PYGQQVGVLG PPGQQAPPPY PGPHPAGPPV IQQPTTPMFV APPPKTQRLL 1550
    HSEAYLKYIE GLSAESNSIS KWDQTLAARR RDVHLSKEQE SRLPSHWLKS 1600
    KGAHTTMADA LWRLRDLMLR DTLNIRQAYN LENV 1634
    Length:1,634
    Mass (Da):187,188
    Last modified:July 27, 2011 - v4
    Checksum:iA905963F22ECD75E
    GO
    Isoform 2 (identifier: Q8BSQ9-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         300-332: RTASNLAAARLTGPSHNKSSLGEERNPTSKYYR → S

    Show »
    Length:1,602
    Mass (Da):183,659
    Checksum:i29EEFCA9EF8A94C9
    GO

    Sequence cautioni

    The sequence AAH29037.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.
    The sequence AAH55456.1 differs from that shown. Reason: Contaminating sequence.
    The sequence AAH55708.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti417 – 4171Y → K in AAH23452. (PubMed:15489334)Curated
    Sequence conflicti695 – 6951D → E in BAC27136. (PubMed:16141072)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei300 – 33233RTASN…SKYYR → S in isoform 2. 2 PublicationsVSP_035471Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC154446 Genomic DNA. No translation available.
    AC154727 Genomic DNA. No translation available.
    BC023452 mRNA. Translation: AAH23452.1.
    BC029037 mRNA. Translation: AAH29037.1. Different termination.
    BC055456 mRNA. Translation: AAH55456.1. Different termination.
    BC055708 mRNA. Translation: AAH55708.1. Different initiation.
    BF451491 mRNA. No translation available.
    CN530699 mRNA. No translation available.
    AK009582 mRNA. Translation: BAB26374.2.
    AK030781 mRNA. Translation: BAC27136.2.
    AK030252 mRNA. No translation available.
    AK166588 mRNA. No translation available.
    UniGeneiMm.27913.

    Genome annotation databases

    EnsembliENSMUST00000112094; ENSMUSP00000107723; ENSMUSG00000042323. [Q8BSQ9-2]
    ENSMUST00000112095; ENSMUSP00000107724; ENSMUSG00000042323. [Q8BSQ9-1]
    UCSCiuc007swl.1. mouse. [Q8BSQ9-1]
    uc007swm.1. mouse. [Q8BSQ9-2]

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC154446 Genomic DNA. No translation available.
    AC154727 Genomic DNA. No translation available.
    BC023452 mRNA. Translation: AAH23452.1 .
    BC029037 mRNA. Translation: AAH29037.1 . Different termination.
    BC055456 mRNA. Translation: AAH55456.1 . Different termination.
    BC055708 mRNA. Translation: AAH55708.1 . Different initiation.
    BF451491 mRNA. No translation available.
    CN530699 mRNA. No translation available.
    AK009582 mRNA. Translation: BAB26374.2 .
    AK030781 mRNA. Translation: BAC27136.2 .
    AK030252 mRNA. No translation available.
    AK166588 mRNA. No translation available.
    UniGenei Mm.27913.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2YQD NMR - A 650-762 [» ]
    ProteinModelPortali Q8BSQ9.
    SMRi Q8BSQ9. Positions 43-154, 176-292, 388-494, 510-628, 651-766, 773-914, 957-1102.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-48885N.
    IntActi Q8BSQ9. 2 interactions.
    MINTi MINT-4112204.

    PTM databases

    PhosphoSitei Q8BSQ9.

    Proteomic databases

    MaxQBi Q8BSQ9.
    PaxDbi Q8BSQ9.
    PRIDEi Q8BSQ9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000112094 ; ENSMUSP00000107723 ; ENSMUSG00000042323 . [Q8BSQ9-2 ]
    ENSMUST00000112095 ; ENSMUSP00000107724 ; ENSMUSG00000042323 . [Q8BSQ9-1 ]
    UCSCi uc007swl.1. mouse. [Q8BSQ9-1 ]
    uc007swm.1. mouse. [Q8BSQ9-2 ]

    Organism-specific databases

    MGIi MGI:1923998. Pbrm1.

    Phylogenomic databases

    eggNOGi COG5076.
    GeneTreei ENSGT00390000003017.
    HOVERGENi HBG079860.
    OrthoDBi EOG78H3S6.

    Miscellaneous databases

    ChiTaRSi PBRM1. mouse.
    EvolutionaryTracei Q8BSQ9.
    PROi Q8BSQ9.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8BSQ9.
    Bgeei Q8BSQ9.
    Genevestigatori Q8BSQ9.

    Family and domain databases

    Gene3Di 1.10.30.10. 1 hit.
    1.20.920.10. 6 hits.
    InterProi IPR001025. BAH_dom.
    IPR001487. Bromodomain.
    IPR018359. Bromodomain_CS.
    IPR009071. HMG_box_dom.
    [Graphical view ]
    Pfami PF01426. BAH. 2 hits.
    PF00439. Bromodomain. 6 hits.
    PF00505. HMG_box. 1 hit.
    [Graphical view ]
    PRINTSi PR00503. BROMODOMAIN.
    SMARTi SM00439. BAH. 2 hits.
    SM00297. BROMO. 6 hits.
    SM00398. HMG. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47095. SSF47095. 1 hit.
    SSF47370. SSF47370. 6 hits.
    PROSITEi PS51038. BAH. 2 hits.
    PS00633. BROMODOMAIN_1. 5 hits.
    PS50014. BROMODOMAIN_2. 6 hits.
    PS50118. HMG_BOX_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6J.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
      Strain: C57BL/6, Czech II and FVB/N.
      Tissue: Brain and Mammary tumor.
    3. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-919 (ISOFORM 1), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 205-512 (ISOFORM 2).
      Strain: C57BL/6J.
      Tissue: Embryo and Tongue.
    4. "Quantitative time-resolved phosphoproteomic analysis of mast cell signaling."
      Cao L., Yu K., Banh C., Nguyen V., Ritz A., Raphael B.J., Kawakami Y., Kawakami T., Salomon A.R.
      J. Immunol. 179:5864-5876(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-1289, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Mast cell.
    5. "An essential switch in subunit composition of a chromatin remodeling complex during neural development."
      Lessard J., Wu J.I., Ranish J.A., Wan M., Winslow M.M., Staahl B.T., Wu H., Aebersold R., Graef I.A., Crabtree G.R.
      Neuron 55:201-215(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY, INTERACTION WITH PHF10, DEVELOPMENTAL STAGE.
    6. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-353 AND SER-355, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Liver.
    7. "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
      Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    8. "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
      Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.
      Mol. Cell. Proteomics 8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Embryonic fibroblast.
    9. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
      Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-414, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Embryonic fibroblast.
    10. "Solution structure of the fifth bromodomain from mouse polybromo-1."
      RIKEN structural genomics initiative (RSGI)
      Submitted (OCT-2007) to the PDB data bank
      Cited for: STRUCTURE BY NMR OF 646-762.

    Entry informationi

    Entry nameiPB1_MOUSE
    AccessioniPrimary (citable) accession number: Q8BSQ9
    Secondary accession number(s): E9QPW1
    , Q05C64, Q05CL6, Q7TMP1, Q7TNU2, Q9CV51
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 23, 2008
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 96 of the entry and version 4 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3