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Q8BRW2

- Q8BRW2_MOUSE

UniProt

Q8BRW2 - Q8BRW2_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Adipoq

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. hormone activity Source: MGI
  2. receptor binding Source: MGI

GO - Biological processi

  1. adiponectin-activated signaling pathway Source: InterPro
  2. brown fat cell differentiation Source: MGI
  3. cellular response to insulin stimulus Source: MGI
  4. fatty acid beta-oxidation Source: MGI
  5. fatty acid oxidation Source: MGI
  6. glucose homeostasis Source: MGI
  7. glucose metabolic process Source: MGI
  8. negative regulation of gluconeogenesis Source: MGI
  9. positive regulation of fatty acid metabolic process Source: MGI
  10. positive regulation of glucose import Source: MGI
  11. positive regulation of I-kappaB kinase/NF-kappaB signaling Source: MGI
  12. positive regulation of signal transduction Source: MGI
  13. protein heterotrimerization Source: MGI
  14. protein homooligomerization Source: MGI
  15. response to glucose Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:AdipoqImported
Synonyms:AcdcImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:106675. Adipoq.

Subcellular locationi

GO - Cellular componenti

  1. collagen trimer Source: UniProtKB-KW
  2. endoplasmic reticulum Source: MGI
  3. extracellular space Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

Expressioni

Gene expression databases

GenevestigatoriQ8BRW2.

Interactioni

Protein-protein interaction databases

IntActiQ8BRW2. 1 interaction.
MINTiMINT-4112137.

Structurei

3D structure databases

ProteinModelPortaliQ8BRW2.
SMRiQ8BRW2. Positions 111-247.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains C1q domain.SAAS annotation

Keywords - Domaini

CollagenSAAS annotation

Phylogenomic databases

HOVERGENiHBG108220.

Family and domain databases

Gene3Di2.60.120.40. 1 hit.
InterProiIPR028572. Adiponectin.
IPR001073. C1q.
IPR008160. Collagen.
IPR008983. Tumour_necrosis_fac-like_dom.
[Graphical view]
PANTHERiPTHR24022:SF81. PTHR24022:SF81. 1 hit.
PfamiPF00386. C1q. 1 hit.
PF01391. Collagen. 1 hit.
[Graphical view]
PRINTSiPR00007. COMPLEMNTC1Q.
SMARTiSM00110. C1Q. 1 hit.
[Graphical view]
SUPFAMiSSF49842. SSF49842. 1 hit.
PROSITEiPS50871. C1Q. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BRW2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLLLQALLFL LILPSHAEDD VTTTEELAPA LVPPPKGTCA GWMAGIPGHP
60 70 80 90 100
GHNGTPGRDG RDGTPGEKGE KGDAGLLGPK GETGGVGMTG AEGPRGFPGT
110 120 130 140 150
PGRKGEPGEA AYVYRSAFSV GLETRVTVPN VPIRFTKIFY NQQNHYDGST
160 170 180 190 200
GKFYCNIPGL YYFSYHITVY MKDVKVSLFK KDKAVLFTYD QYQEKNVDQA
210 220 230 240
SGSVLLHLEV GDQVWLQVYG DGDHNGLYAD NVNDSTFTGF LLYHDTN
Length:247
Mass (Da):26,751
Last modified:March 1, 2003 - v1
Checksum:i0D3FA64C789CAEF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK041214 mRNA. Translation: BAC30866.1.
UniGeneiMm.3969.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK041214 mRNA. Translation: BAC30866.1 .
UniGenei Mm.3969.

3D structure databases

ProteinModelPortali Q8BRW2.
SMRi Q8BRW2. Positions 111-247.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q8BRW2. 1 interaction.
MINTi MINT-4112137.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:106675. Adipoq.

Phylogenomic databases

HOVERGENi HBG108220.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Genevestigatori Q8BRW2.

Family and domain databases

Gene3Di 2.60.120.40. 1 hit.
InterProi IPR028572. Adiponectin.
IPR001073. C1q.
IPR008160. Collagen.
IPR008983. Tumour_necrosis_fac-like_dom.
[Graphical view ]
PANTHERi PTHR24022:SF81. PTHR24022:SF81. 1 hit.
Pfami PF00386. C1q. 1 hit.
PF01391. Collagen. 1 hit.
[Graphical view ]
PRINTSi PR00007. COMPLEMNTC1Q.
SMARTi SM00110. C1Q. 1 hit.
[Graphical view ]
SUPFAMi SSF49842. SSF49842. 1 hit.
PROSITEi PS50871. C1Q. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Aorta and veinImported.

Entry informationi

Entry nameiQ8BRW2_MOUSE
AccessioniPrimary (citable) accession number: Q8BRW2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)