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Q8BRW2

- Q8BRW2_MOUSE

UniProt

Q8BRW2 - Q8BRW2_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Adipoq

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. hormone activity Source: MGI
    2. protein binding Source: MGI
    3. receptor binding Source: MGI

    GO - Biological processi

    1. adiponectin-activated signaling pathway Source: InterPro
    2. brown fat cell differentiation Source: MGI
    3. cellular response to insulin stimulus Source: MGI
    4. fatty acid beta-oxidation Source: MGI
    5. fatty acid oxidation Source: MGI
    6. glucose homeostasis Source: MGI
    7. glucose metabolic process Source: MGI
    8. negative regulation of gluconeogenesis Source: MGI
    9. positive regulation of fatty acid metabolic process Source: MGI
    10. positive regulation of glucose import Source: MGI
    11. positive regulation of I-kappaB kinase/NF-kappaB signaling Source: MGI
    12. positive regulation of signal transduction Source: MGI
    13. protein heterotrimerization Source: MGI
    14. protein homooligomerization Source: MGI
    15. response to glucose Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:AdipoqImported
    Synonyms:AcdcImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:106675. Adipoq.

    Subcellular locationi

    GO - Cellular componenti

    1. collagen trimer Source: UniProtKB-KW
    2. endoplasmic reticulum Source: MGI
    3. extracellular space Source: MGI

    Keywords - Cellular componenti

    SecretedSAAS annotation

    Expressioni

    Gene expression databases

    GenevestigatoriQ8BRW2.

    Interactioni

    Protein-protein interaction databases

    IntActiQ8BRW2. 1 interaction.
    MINTiMINT-4112137.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8BRW2.
    SMRiQ8BRW2. Positions 111-247.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains C1q domain.SAAS annotation

    Keywords - Domaini

    CollagenSAAS annotation

    Phylogenomic databases

    HOVERGENiHBG108220.
    InParanoidiQ8BRW2.

    Family and domain databases

    Gene3Di2.60.120.40. 1 hit.
    InterProiIPR028572. Adiponectin.
    IPR001073. C1q.
    IPR008160. Collagen.
    IPR008983. Tumour_necrosis_fac-like_dom.
    [Graphical view]
    PANTHERiPTHR24022:SF81. PTHR24022:SF81. 1 hit.
    PfamiPF00386. C1q. 1 hit.
    PF01391. Collagen. 1 hit.
    [Graphical view]
    PRINTSiPR00007. COMPLEMNTC1Q.
    SMARTiSM00110. C1Q. 1 hit.
    [Graphical view]
    SUPFAMiSSF49842. SSF49842. 1 hit.
    PROSITEiPS50871. C1Q. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8BRW2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLLLQALLFL LILPSHAEDD VTTTEELAPA LVPPPKGTCA GWMAGIPGHP    50
    GHNGTPGRDG RDGTPGEKGE KGDAGLLGPK GETGGVGMTG AEGPRGFPGT 100
    PGRKGEPGEA AYVYRSAFSV GLETRVTVPN VPIRFTKIFY NQQNHYDGST 150
    GKFYCNIPGL YYFSYHITVY MKDVKVSLFK KDKAVLFTYD QYQEKNVDQA 200
    SGSVLLHLEV GDQVWLQVYG DGDHNGLYAD NVNDSTFTGF LLYHDTN 247
    Length:247
    Mass (Da):26,751
    Last modified:March 1, 2003 - v1
    Checksum:i0D3FA64C789CAEF3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK041214 mRNA. Translation: BAC30866.1.
    UniGeneiMm.3969.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK041214 mRNA. Translation: BAC30866.1 .
    UniGenei Mm.3969.

    3D structure databases

    ProteinModelPortali Q8BRW2.
    SMRi Q8BRW2. Positions 111-247.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q8BRW2. 1 interaction.
    MINTi MINT-4112137.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:106675. Adipoq.

    Phylogenomic databases

    HOVERGENi HBG108220.
    InParanoidi Q8BRW2.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q8BRW2.

    Family and domain databases

    Gene3Di 2.60.120.40. 1 hit.
    InterProi IPR028572. Adiponectin.
    IPR001073. C1q.
    IPR008160. Collagen.
    IPR008983. Tumour_necrosis_fac-like_dom.
    [Graphical view ]
    PANTHERi PTHR24022:SF81. PTHR24022:SF81. 1 hit.
    Pfami PF00386. C1q. 1 hit.
    PF01391. Collagen. 1 hit.
    [Graphical view ]
    PRINTSi PR00007. COMPLEMNTC1Q.
    SMARTi SM00110. C1Q. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49842. SSF49842. 1 hit.
    PROSITEi PS50871. C1Q. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Aorta and veinImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Aorta and veinImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Aorta and veinImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Aorta and veinImported.
    5. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Aorta and veinImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Aorta and veinImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Aorta and veinImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Aorta and veinImported.

    Entry informationi

    Entry nameiQ8BRW2_MOUSE
    AccessioniPrimary (citable) accession number: Q8BRW2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)