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Q8BRL5

- Q8BRL5_MOUSE

UniProt

Q8BRL5 - Q8BRL5_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Rora

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: MGI
  2. ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity Source: InterPro
  3. oxysterol binding Source: Ensembl
  4. sequence-specific DNA binding Source: Ensembl
  5. sequence-specific DNA binding transcription factor activity Source: MGI
  6. steroid hormone receptor activity Source: InterPro

GO - Biological processi

  1. angiogenesis Source: Ensembl
  2. cellular response to hypoxia Source: Ensembl
  3. cellular response to sterol Source: Ensembl
  4. cerebellar Purkinje cell differentiation Source: MGI
  5. cGMP metabolic process Source: MGI
  6. circadian rhythm Source: Ensembl
  7. muscle cell differentiation Source: Ensembl
  8. negative regulation of I-kappaB kinase/NF-kappaB signaling Source: Ensembl
  9. negative regulation of inflammatory response Source: Ensembl
  10. nitric oxide biosynthetic process Source: MGI
  11. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  12. positive regulation vascular endothelial growth factor production Source: Ensembl
  13. regulation of macrophage activation Source: MGI
  14. regulation of transcription, DNA-templated Source: MGI
  15. triglyceride homeostasis Source: Ensembl
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:RoraImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:104661. Rora.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Expressioni

Gene expression databases

BgeeiQ8BRL5.
ExpressionAtlasiQ8BRL5. baseline and differential.
GenevestigatoriQ8BRL5.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliQ8BRL5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG106848.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
InterProiIPR008946. Nucl_hormone_rcpt_ligand-bd.
IPR000536. Nucl_hrmn_rcpt_lig-bd_core.
IPR003079. ROR_rcpt.
IPR001723. Str_hrmn_rcpt.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
[Graphical view]
PRINTSiPR01293. RORNUCRECPTR.
PR00398. STRDHORMONER.
SMARTiSM00430. HOLI. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q8BRL5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
TPEGSKADSA VSSFYLDIQP SPDQSGLDIN GIKPEPICDY TPASGFFPYC
60 70 80 90 100
SFTNGETSPT VSMAELEHLA QNISKSHLET CQYLREELQQ ITWQTFLQEE
110 120 130 140 150
IENYQNKQRE VMWQLCAIKI TEAIQYVVEF AKRIDGFMEL CQNDQIVLLK
160 170 180 190 200
AGSLEVVFIR MCRAFDSQNN TVYFDGKYAS PDVFKSLGCE DFISFVFEFG
210 220 230 240 250
KSLCSMHLTE DEIALFSAFV LMSADRSWLQ EKVKIEKLQQ KIQLALQHVL
260 270 280 290 300
QKNHREDGIL TKLICKVSTL RALCGRHTEK LMAFKAIYPD IVRLHFPPLY
310
KELFTSEFEP AMQIDG
Length:316
Mass (Da):36,183
Last modified:March 1, 2003 - v1
Checksum:i1CC922302653CCDD
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK043990 mRNA. Translation: BAC31728.1.
UniGeneiMm.378450.
Mm.391890.
Mm.427266.
Mm.445802.
Mm.491288.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK043990 mRNA. Translation: BAC31728.1 .
UniGenei Mm.378450.
Mm.391890.
Mm.427266.
Mm.445802.
Mm.491288.

3D structure databases

ProteinModelPortali Q8BRL5.
ModBasei Search...
MobiDBi Search...

Chemistry

BindingDBi Q8BRL5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:104661. Rora.

Phylogenomic databases

HOVERGENi HBG106848.

Miscellaneous databases

ChiTaRSi RORA. mouse.
SOURCEi Search...

Gene expression databases

Bgeei Q8BRL5.
ExpressionAtlasi Q8BRL5. baseline and differential.
Genevestigatori Q8BRL5.

Family and domain databases

Gene3Di 1.10.565.10. 1 hit.
InterProi IPR008946. Nucl_hormone_rcpt_ligand-bd.
IPR000536. Nucl_hrmn_rcpt_lig-bd_core.
IPR003079. ROR_rcpt.
IPR001723. Str_hrmn_rcpt.
[Graphical view ]
Pfami PF00104. Hormone_recep. 1 hit.
[Graphical view ]
PRINTSi PR01293. RORNUCRECPTR.
PR00398. STRDHORMONER.
SMARTi SM00430. HOLI. 1 hit.
[Graphical view ]
SUPFAMi SSF48508. SSF48508. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: CortexImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: CortexImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: CortexImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: CortexImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: CortexImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: CortexImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: CortexImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: CortexImported.

Entry informationi

Entry nameiQ8BRL5_MOUSE
AccessioniPrimary (citable) accession number: Q8BRL5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)