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Protein

Protein RD3

Gene

Rd3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • response to stimulus Source: UniProtKB-KW
  • retina development in camera-type eye Source: MGI
  • visual perception Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Sensory transduction, Vision

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RD3
Gene namesi
Name:Rd3
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1921273. Rd3.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 195195Protein RD3PRO_0000089249Add
BLAST

Proteomic databases

PaxDbiQ8BRE0.
PRIDEiQ8BRE0.

PTM databases

PhosphoSiteiQ8BRE0.

Expressioni

Tissue specificityi

Expressed in the retina and in particular in the inner nuclear layer, in the outer nuclear layer and in the ganglion cell layer.1 Publication

Gene expression databases

BgeeiQ8BRE0.
CleanExiMM_RD3.
ExpressionAtlasiQ8BRE0. baseline and differential.
GenevisibleiQ8BRE0. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000050188.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili22 – 5433Sequence analysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi178 – 1814Poly-Pro

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IK8N. Eukaryota.
ENOG4111AQS. LUCA.
GeneTreeiENSGT00390000002089.
HOGENOMiHOG000247021.
HOVERGENiHBG088417.
InParanoidiQ8BRE0.
OrthoDBiEOG7BW0KM.
PhylomeDBiQ8BRE0.

Family and domain databases

InterProiIPR028092. RD3.
[Graphical view]
PfamiPF14473. RD3. 1 hit.
[Graphical view]
ProDomiPD822638. PD822638. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Q8BRE0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLIPWLRWN DTPPRLSART PAEMVLETLM MELAGQMREV ERQQRERRSA
60 70 80 90 100
VRKICTGVDY SWLANTPRPT YDISPGERLQ LEDVCAKIHP SYCGPAILRF
110 120 130 140 150
RQLLAEREPE VQEVARLFRS VLQEALEKMK QEEEAHKLTR QWSLRPRGSL
160 170 180 190
SSFKTRARIA PFASDIRTIS EDVERDAPPP PRTWSMPEFR APQAD
Length:195
Mass (Da):22,669
Last modified:March 1, 2003 - v1
Checksum:i6C33550846800762
GO

Sequence cautioni

The sequence BAA92758.1 differs from that shown. Reason: Frameshift at position 87. Curated
The sequence BAB29312.2 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB030195 mRNA. Translation: BAA92758.1. Frameshift.
AK014383 mRNA. Translation: BAB29312.2. Different initiation.
AK045045 mRNA. Translation: BAC32196.1.
BC103778 mRNA. Translation: AAI03779.1.
BC116935 mRNA. Translation: AAI16936.1.
BC116937 mRNA. Translation: AAI16938.1.
CCDSiCCDS15626.3.
RefSeqiNP_001171371.2. NM_001177900.2.
NP_001290061.1. NM_001303132.1.
NP_076216.3. NM_023727.4.
XP_006497268.1. XM_006497205.2.
XP_006497269.1. XM_006497206.2.
XP_011237226.1. XM_011238924.1.
UniGeneiMm.274393.
Mm.475401.

Genome annotation databases

EnsembliENSMUST00000180463; ENSMUSP00000138049; ENSMUSG00000049353.
GeneIDi74023.
KEGGimmu:74023.
UCSCiuc007edd.3. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB030195 mRNA. Translation: BAA92758.1. Frameshift.
AK014383 mRNA. Translation: BAB29312.2. Different initiation.
AK045045 mRNA. Translation: BAC32196.1.
BC103778 mRNA. Translation: AAI03779.1.
BC116935 mRNA. Translation: AAI16936.1.
BC116937 mRNA. Translation: AAI16938.1.
CCDSiCCDS15626.3.
RefSeqiNP_001171371.2. NM_001177900.2.
NP_001290061.1. NM_001303132.1.
NP_076216.3. NM_023727.4.
XP_006497268.1. XM_006497205.2.
XP_006497269.1. XM_006497206.2.
XP_011237226.1. XM_011238924.1.
UniGeneiMm.274393.
Mm.475401.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000050188.

PTM databases

PhosphoSiteiQ8BRE0.

Proteomic databases

PaxDbiQ8BRE0.
PRIDEiQ8BRE0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000180463; ENSMUSP00000138049; ENSMUSG00000049353.
GeneIDi74023.
KEGGimmu:74023.
UCSCiuc007edd.3. mouse.

Organism-specific databases

CTDi343035.
MGIiMGI:1921273. Rd3.

Phylogenomic databases

eggNOGiENOG410IK8N. Eukaryota.
ENOG4111AQS. LUCA.
GeneTreeiENSGT00390000002089.
HOGENOMiHOG000247021.
HOVERGENiHBG088417.
InParanoidiQ8BRE0.
OrthoDBiEOG7BW0KM.
PhylomeDBiQ8BRE0.

Miscellaneous databases

PROiQ8BRE0.
SOURCEiSearch...

Gene expression databases

BgeeiQ8BRE0.
CleanExiMM_RD3.
ExpressionAtlasiQ8BRE0. baseline and differential.
GenevisibleiQ8BRE0. MM.

Family and domain databases

InterProiIPR028092. RD3.
[Graphical view]
PfamiPF14473. RD3. 1 hit.
[Graphical view]
ProDomiPD822638. PD822638. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains."
    Inoue S., Sano H., Ohta M.
    Biochem. Biophys. Res. Commun. 268:553-561(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Brain.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Head.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain and Eye.
  4. "Identification and characterization of C1orf36, a transcript highly expressed in photoreceptor cells, and mutation analysis in retinitis pigmentosa."
    Lavorgna G., Lestingi M., Ziviello C., Testa F., Simonelli F., Manitto M.P., Brancato R., Ferrari M., Rinaldi E., Ciccodicola A., Banfi S.
    Biochem. Biophys. Res. Commun. 308:414-421(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.

Entry informationi

Entry nameiRD3_MOUSE
AccessioniPrimary (citable) accession number: Q8BRE0
Secondary accession number(s): Q3SYJ8, Q9CRS3, Q9JMF2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: March 1, 2003
Last modified: June 8, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

Shows growth-inhibitory effect on E.coli when its expression is induced.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.