Unreviewed, UniProtKB/TrEMBL Q8BRD8 (Q8BRD8_MOUSE)

Names and origin

Protein names

Submitted name:
    Putative uncharacterized protein EMBL BAC32198.1

Gene names

Name:

Apc MGI 88039

Organism

Mus musculus (Mouse) EMBL BAC32198.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	489 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	T cell differentiation in the thymus Inferred from mutant phenotype. Source: MGI Wnt receptor signaling pathway through beta-catenin Inferred from mutant phenotype. Source: MGI anterior/posterior pattern formation Inferred from mutant phenotype. Source: MGI axis specification Inferred from mutant phenotype. Source: MGI axonogenesis Inferred from mutant phenotype. Source: MGI cell cycle arrest Inferred from electronic annotation. Source: Compara cell migration Inferred from mutant phenotype. Source: MGI chromosome organization Inferred from genetic interaction. Source: MGI cytokinesis after mitosis Inferred from mutant phenotype. Source: MGI dorsal/ventral pattern formation Inferred from mutant phenotype. Source: MGI establishment or maintenance of cell polarity Inferred from electronic annotation. Source: Compara hair follicle development Inferred from mutant phenotype. Source: MGI kidney development Inferred from mutant phenotype. Source: MGI mitotic cell cycle spindle assembly checkpoint Inferred from electronic annotation. Source: Compara mitotic metaphase/anaphase transition Inferred from genetic interaction. Source: MGI muscle homeostasis Inferred from genetic interaction. Source: MGI negative regulation of MAPKKK cascade Inferred from genetic interaction. Source: MGI negative regulation of Wnt receptor signaling pathway Inferred from genetic interaction. Source: MGI negative regulation of apoptosis Inferred from mutant phenotype. Source: MGI negative regulation of cyclin-dependent protein kinase activity Inferred from electronic annotation. Source: Compara negative regulation of epithelial cell proliferation involved in prostate gland development Inferred from mutant phenotype. Source: MGI negative regulation of microtubule depolymerization Inferred from mutant phenotype. Source: MGI negative regulation of odontogenesis Inferred from mutant phenotype. Source: MGI positive regulation of apoptosis Inferred from mutant phenotype. Source: MGI positive regulation of cell adhesion Inferred from mutant phenotype. Source: MGI positive regulation of cell division Inferred from mutant phenotype. Source: MGI positive regulation of cell migration Inferred from mutant phenotype. Source: MGI positive regulation of epithelial cell differentiation Inferred from genetic interaction. Source: MGI positive regulation of microtubule polymerization Inferred from mutant phenotype. Source: MGI positive regulation of protein catabolic process Inferred from mutant phenotype. Source: MGI positive regulation of pseudopodium assembly Inferred from electronic annotation. Source: Compara protein complex assembly Inferred from electronic annotation. Source: Compara proximal/distal pattern formation Inferred from mutant phenotype. Source: MGI regulation of attachment of spindle microtubules to kinetochore Inferred from mutant phenotype. Source: MGI regulation of nitrogen compound metabolic process Inferred from mutant phenotype. Source: MGI regulation of osteoblast differentiation Inferred from mutant phenotype. Source: MGI regulation of osteoclast differentiation Inferred from mutant phenotype. Source: MGI response to DNA damage stimulus Inferred from electronic annotation. Source: Compara response to drug Inferred from electronic annotation. Source: Compara retina development in camera-type eye Inferred from mutant phenotype. Source: MGI skin development Inferred from mutant phenotype. Source: MGI somatic stem cell maintenance Inferred from genetic interaction. Source: MGI thymus development Inferred from mutant phenotype. Source: MGI
Cellular component	Axin-APC-beta-catenin-GSK3B complex Inferred from electronic annotation. Source: Compara axon part Inferred from direct assay. Source: MGI beta-catenin destruction complex Inferred from electronic annotation. Source: Compara cell projection membrane Inferred from direct assay. Source: MGI centrosome Inferred from electronic annotation. Source: Compara cytoplasmic microtubule Inferred from direct assay. Source: MGI growth cone Inferred from direct assay. Source: MGI kinetochore Inferred from electronic annotation. Source: Compara lateral plasma membrane Inferred from electronic annotation. Source: Compara nucleus Inferred from direct assay. Source: MGI
Molecular function	beta-catenin binding Inferred from direct assay. Source: MGI microtubule binding Inferred from electronic annotation. Source: Compara protein kinase binding Inferred from electronic annotation. Source: Compara protein kinase regulator activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8BRD8-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: F7C9949868B01993	FASTA	489	55,218
	10 20 30 40 50 60 MAAASYDQLL KQVEALKMEN SNLRQELEDN SNHLTKLETE ASNMKEVLKQ LQGSIEDETM 70 80 90 100 110 120 TSGQIDLLER LKEFNLDSNF PGVKLRSKMS LRSYGSREGS VSSRSGECSP VPMGSFPRRT 130 140 150 160 170 180 FVNGSRESTG YLEELEKERS LLLADLDKEE KEKDWYYAQL QNLTKRIDSL PLTENFSLQT 190 200 210 220 230 240 DMTRRQLEYE ARQIRAAMEE QLGTCQDMEK RAQRRIARIQ QIEKDILRVR QLLQSQAAEA 250 260 270 280 290 300 ERSSQSRHDA ASHEAGRQHE GHGVAESNTA ASSSGQSPAT RVDHETASVL SSSGTHSAPR 310 320 330 340 350 360 RLTSHLGTKV EMVYSLLSML GTHDKDDMSR TLLAMSSSQD SCISMRQSGC LPLLIQLLHG 370 380 390 400 410 420 NDKDSVLLGN SRGSKEARAR ASAALHNIIH SQPDDKRGRR EIRVLHLLEQ IRAYCETCWE 430 440 450 460 470 480 WQEAHEQGMD QDKNPMPAPV EHQICPAVCV LMKLSFDEEH RHAMNELGKI KAFLTPQIHA AECLKHKRN

References

[1]

"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6J EMBL BAC32198.1. Tissue: Parthenogenote EMBL BAC32198.1.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK045053 mRNA. Translation: BAC32198.1.
IPI	IPI00896736.
UniGene	Mm.384171
3D structure databases
HSSP	HSSP built from PDB template 1DEB based on UniProtKB P25054.
SMR	Q8BRD8. Positions 2-55, 128-237.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8BRD8.
Genome annotation databases
Ensembl	ENSMUST00000079362; ENSMUSP00000078337; ENSMUSG00000005871; Mus musculus. [Genome view]
UCSC	uc008ekd.1. mouse.
Organism-specific databases
MGI	MGI:88039. Apc.
Phylogenomic databases
HOVERGEN	Q8BRD8.
InParanoid	Q8BRD8.
Gene expression databases
ArrayExpress	Q8BRD8.
Bgee	Q8BRD8.
Genevestigator	Q8BRD8.
Family and domain databases
InterPro	IPR011989. ARM-like. IPR016024. ARM-type_fold. [Graphical view]
Gene3D	G3DSA:1.25.10.10. ARM-like. 1 hit.
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

Q8BRD8_MOUSE

Accession

Primary (citable) accession number: Q8BRD8

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	January 19, 2010
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)