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Protein

Protein MAATS1

Gene

Maats1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May play a role in spermatogenesis.1 Publication

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MAATS1
Alternative name(s):
AMY-1-associating protein expressed in testis 1 homolog
Short name:
AAT-1
MYCBP/AMY-1-associated testis-expressed protein 1
Gene namesi
Name:Maats1
Synonyms:Aat1, Spata26
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:2443598. Maats1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 783783Protein MAATS1PRO_0000064419Add
BLAST

Proteomic databases

MaxQBiQ8BRC6.
PaxDbiQ8BRC6.
PRIDEiQ8BRC6.

PTM databases

iPTMnetiQ8BRC6.
PhosphoSiteiQ8BRC6.

Expressioni

Tissue specificityi

Expressed in the testis, in cells involved in spermatogenesis.1 Publication

Developmental stagei

Expression begins in 1 week old mice.1 Publication

Gene expression databases

BgeeiQ8BRC6.
CleanExiMM_4932425I24RIK.
GenevisibleiQ8BRC6. MM.

Interactioni

Subunit structurei

Part of a complex containing MYCBP, AKAP1 and PRKAR2B.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000023501.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili288 – 31225Sequence analysisAdd
BLAST
Coiled coili551 – 57121Sequence analysisAdd
BLAST
Coiled coili651 – 68232Sequence analysisAdd
BLAST
Coiled coili737 – 76327Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IG6N. Eukaryota.
ENOG410XQ2Y. LUCA.
GeneTreeiENSGT00390000003024.
HOGENOMiHOG000185870.
InParanoidiQ8BRC6.
OMAiKHLNARW.
OrthoDBiEOG776SPK.
TreeFamiTF328648.

Family and domain databases

InterProiIPR026720. MAATS1.
IPR032840. MAATS1_dom.
[Graphical view]
PANTHERiPTHR22455:SF10. PTHR22455:SF10. 1 hit.
PfamiPF14738. PaaSYMP. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q8BRC6-2) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSQTVTIQEP RPNDQRIPYQ CREVRRAKGG FANRTYDYLY DPLFIVSSER
60 70 80 90 100
DHAQANIQAT LIRSRLKKVP NFRSMFSNLF HHPRYSMYWS KTDPVPLHVT
110 120 130 140 150
REWRGQEAKH KEVLRLQAAM DTSFQMPKEK DEDPDVSGKN RYKFFDRPFL
160 170 180 190 200
PFLQQMPLNV VLSPVKTQPL LLTPESSKYA IIPTKSTVAT QTDYRDADVQ
210 220 230 240 250
TDPYSPEYVV CQDTIPELLT LANLTWGRGL PAGQAEVEII ERAREKRAWE
260 270 280 290 300
ATLPPLNDSV QAEKRRKMMN AMERKEWAFR EGEIEKLQEL RLEVLKQLLK
310 320 330 340 350
RREEDQNELN MRHLNDQWYK LQEAKEAKVA QIRHKHVSDI RKLMGKGKNI
360 370 380 390 400
EGKLQRRDII SDYSNFASQV YGPLSRLGRF PDNNSEDFVV RNHYLNTYEG
410 420 430 440 450
LVELESSLPD FVTQPRIKPP KPQIITTKAG FLKRTARMDY ELAEVHKALV
460 470 480 490 500
DKKNKGLEGT KSLRFLQKNP ISQARLPTPS LEMTSYEEGE IEMAVIYLQK
510 520 530 540 550
LLRGRVVQNM MFEGKEKRLE LILELRTSHA LQEDDKLVKK AEKQVTLALQ
560 570 580 590 600
RQRNLHEDKL SVIENHLGDL EGRVLADMFD FLSKELVRLQ EERRIHAFAM
610 620 630 640 650
LAERQRRMRE AEESGRRQVE QKRLQQEDMI FKEVIKVHQS TVTSYLEDII
660 670 680 690 700
LNTEERTAEE QARKEIEKIA EEINNIAYEM ENRRTYLQSE EIVAELVYSF
710 720 730 740 750
LIPEVQKDFV KEKVRNAQRK HILAAHEIIH SNTETMLEEQ VYKELQSEDF
760 770 780
ELEEEAESLD SEVPTVSVSK TSTIKPTQDE GEG
Note: No experimental confirmation available.
Length:783
Mass (Da):91,623
Last modified:March 6, 2013 - v3
Checksum:i12237970B7041685
GO
Isoform 2 (identifier: Q8BRC6-1) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     339-345: DIRKLMG → EAEEMAQ
     346-783: Missing.

Show »
Length:345
Mass (Da):40,598
Checksum:i216993D183D22766
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti238 – 2381E → K in BAC32231 (PubMed:16141072).Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei339 – 3457DIRKLMG → EAEEMAQ in isoform 2. 1 PublicationVSP_045751
Alternative sequencei346 – 783438Missing in isoform 2. 1 PublicationVSP_045752Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK045121 mRNA. Translation: BAC32231.1.
AC154809 Genomic DNA. No translation available.
CCDSiCCDS37341.1. [Q8BRC6-2]
RefSeqiNP_001074494.1. NM_001081025.1. [Q8BRC6-2]
UniGeneiMm.294342.

Genome annotation databases

EnsembliENSMUST00000023501; ENSMUSP00000023501; ENSMUSG00000022805. [Q8BRC6-2]
ENSMUST00000114740; ENSMUSP00000110388; ENSMUSG00000022805. [Q8BRC6-1]
GeneIDi320214.
KEGGimmu:320214.
UCSCiuc007zer.1. mouse. [Q8BRC6-2]
uc007zes.1. mouse. [Q8BRC6-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK045121 mRNA. Translation: BAC32231.1.
AC154809 Genomic DNA. No translation available.
CCDSiCCDS37341.1. [Q8BRC6-2]
RefSeqiNP_001074494.1. NM_001081025.1. [Q8BRC6-2]
UniGeneiMm.294342.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000023501.

PTM databases

iPTMnetiQ8BRC6.
PhosphoSiteiQ8BRC6.

Proteomic databases

MaxQBiQ8BRC6.
PaxDbiQ8BRC6.
PRIDEiQ8BRC6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000023501; ENSMUSP00000023501; ENSMUSG00000022805. [Q8BRC6-2]
ENSMUST00000114740; ENSMUSP00000110388; ENSMUSG00000022805. [Q8BRC6-1]
GeneIDi320214.
KEGGimmu:320214.
UCSCiuc007zer.1. mouse. [Q8BRC6-2]
uc007zes.1. mouse. [Q8BRC6-1]

Organism-specific databases

CTDi89876.
MGIiMGI:2443598. Maats1.

Phylogenomic databases

eggNOGiENOG410IG6N. Eukaryota.
ENOG410XQ2Y. LUCA.
GeneTreeiENSGT00390000003024.
HOGENOMiHOG000185870.
InParanoidiQ8BRC6.
OMAiKHLNARW.
OrthoDBiEOG776SPK.
TreeFamiTF328648.

Miscellaneous databases

NextBioi396283.
PROiQ8BRC6.
SOURCEiSearch...

Gene expression databases

BgeeiQ8BRC6.
CleanExiMM_4932425I24RIK.
GenevisibleiQ8BRC6. MM.

Family and domain databases

InterProiIPR026720. MAATS1.
IPR032840. MAATS1_dom.
[Graphical view]
PANTHERiPTHR22455:SF10. PTHR22455:SF10. 1 hit.
PfamiPF14738. PaaSYMP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Strain: C57BL/6J.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex between AMY-1, A-kinase anchor protein 84 and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase."
    Yukitake H., Furusawa M., Taira T., Iguchi-Ariga S.M.M., Ariga H.
    J. Biol. Chem. 277:45480-45492(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Testis.

Entry informationi

Entry nameiMAAT1_MOUSE
AccessioniPrimary (citable) accession number: Q8BRC6
Secondary accession number(s): E9PZ32, E9QND1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: March 6, 2013
Last modified: January 20, 2016
This is version 78 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.