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Q8BQ27

- Q8BQ27_MOUSE

UniProt

Q8BQ27 - Q8BQ27_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Foxp2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: MGI
    2. protein heterodimerization activity Source: MGI
    3. protein homodimerization activity Source: MGI
    4. sequence-specific DNA binding Source: InterPro
    5. sequence-specific DNA binding transcription factor activity Source: MGI

    GO - Biological processi

    1. camera-type eye development Source: MGI
    2. cerebellum development Source: MGI
    3. growth Source: MGI
    4. lung alveolus development Source: MGI
    5. lung development Source: MGI
    6. negative regulation of transcription, DNA-templated Source: MGI
    7. negative regulation of transcription from RNA polymerase II promoter Source: MGI
    8. positive regulation of epithelial cell proliferation Source: MGI
    9. positive regulation of epithelial cell proliferation involved in lung morphogenesis Source: MGI
    10. positive regulation of mesenchymal cell proliferation Source: MGI
    11. post-embryonic development Source: MGI
    12. righting reflex Source: MGI
    13. skeletal muscle tissue development Source: MGI
    14. smooth muscle tissue development Source: MGI
    15. vocal learning Source: MGI

    Keywords - Ligandi

    DNA-bindingSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Foxp2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:2148705. Foxp2.

    Expressioni

    Gene expression databases

    GenevestigatoriQ8BQ27.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8BQ27.
    SMRiQ8BQ27. Positions 509-555.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains fork-head DNA-binding domain.SAAS annotation

    Phylogenomic databases

    HOVERGENiHBG051657.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    InterProiIPR001766. TF_fork_head.
    IPR011991. WHTH_DNA-bd_dom.
    IPR015880. Znf_C2H2-like.
    [Graphical view]
    PfamiPF00250. Fork_head. 1 hit.
    [Graphical view]
    PRINTSiPR00053. FORKHEAD.
    SMARTiSM00339. FH. 1 hit.
    SM00355. ZnF_C2H2. 1 hit.
    [Graphical view]
    PROSITEiPS50039. FORK_HEAD_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8BQ27-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMQESATETI SNSSMNQNGM STLSSQLDAG SRDGRSSGDT SSEVSTVELL    50
    HLQQQQALQA ARQLLLQQQT SGLKSPKSSE KQRPLQVPVS VAMMTPQVIT 100
    PQQMQQILQQ QVLSPQQLQA LLQQQQAVML QQSKWFIQQQ LQEFYKKQQE 150
    QLHLQLLQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQHP 200
    GKQAKEQQQQ QQQQQLAAQQ LVFQQQLLQM QQLQQQQHLL SLQRQGLISI 250
    PPGQAALPVQ SLPQAGLSPA EIQQLWKEVT GVHSMEDNGI KHGGLDLTTN 300
    NSSSTTSSTT SKASPPITHH SIVNGQSSVL NARRDSSSHE ETGASHTLYG 350
    HGVCKWPGCE SICEDFGQFL KHLNNEHALD DRSTAQCRVQ MQVVQQLEIQ 400
    LSKERERLQA MMTHLHMRPS EPKPSPKPLN LVSSVTMSKN MLETSPQSLP 450
    QTPTTPTAPV TPITQGPSVI TPASVPNVGA IRRRHSDKYN IPMSSEIAPN 500
    YEFYKNADVR PPFTYATLIR QAIMESSDRQ LTLNEIYSWF TRTFAYFRRN 550
    AATWKVTPKS SCSPSETQHS SFQIAPGAFI YMTQAD 586
    Length:586
    Mass (Da):66,107
    Last modified:March 1, 2003 - v1
    Checksum:iF75391FFBB2A98E3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK051668 mRNA. Translation: BAC34711.1.
    UniGeneiMm.332919.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK051668 mRNA. Translation: BAC34711.1 .
    UniGenei Mm.332919.

    3D structure databases

    ProteinModelPortali Q8BQ27.
    SMRi Q8BQ27. Positions 509-555.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:2148705. Foxp2.

    Phylogenomic databases

    HOVERGENi HBG051657.

    Miscellaneous databases

    ChiTaRSi FOXP2. mouse.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q8BQ27.

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    InterProi IPR001766. TF_fork_head.
    IPR011991. WHTH_DNA-bd_dom.
    IPR015880. Znf_C2H2-like.
    [Graphical view ]
    Pfami PF00250. Fork_head. 1 hit.
    [Graphical view ]
    PRINTSi PR00053. FORKHEAD.
    SMARTi SM00339. FH. 1 hit.
    SM00355. ZnF_C2H2. 1 hit.
    [Graphical view ]
    PROSITEi PS50039. FORK_HEAD_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Spinal ganglionImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Spinal ganglionImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Spinal ganglionImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Spinal ganglionImported.
    5. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Spinal ganglionImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Spinal ganglionImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Spinal ganglionImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Spinal ganglionImported.

    Entry informationi

    Entry nameiQ8BQ27_MOUSE
    AccessioniPrimary (citable) accession number: Q8BQ27
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)