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Q8BQ27

- Q8BQ27_MOUSE

UniProt

Q8BQ27 - Q8BQ27_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Foxp2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: MGI
  2. protein heterodimerization activity Source: MGI
  3. protein homodimerization activity Source: MGI
  4. sequence-specific DNA binding Source: InterPro
  5. sequence-specific DNA binding transcription factor activity Source: MGI

GO - Biological processi

  1. camera-type eye development Source: MGI
  2. cerebellum development Source: MGI
  3. growth Source: MGI
  4. lung alveolus development Source: MGI
  5. lung development Source: MGI
  6. negative regulation of transcription, DNA-templated Source: MGI
  7. negative regulation of transcription from RNA polymerase II promoter Source: MGI
  8. positive regulation of epithelial cell proliferation Source: MGI
  9. positive regulation of epithelial cell proliferation involved in lung morphogenesis Source: MGI
  10. positive regulation of mesenchymal cell proliferation Source: MGI
  11. post-embryonic development Source: MGI
  12. righting reflex Source: MGI
  13. skeletal muscle tissue development Source: MGI
  14. smooth muscle tissue development Source: MGI
  15. vocal learning Source: MGI
Complete GO annotation...

Keywords - Ligandi

DNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Foxp2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2148705. Foxp2.

Expressioni

Gene expression databases

GenevestigatoriQ8BQ27.

Structurei

3D structure databases

ProteinModelPortaliQ8BQ27.
SMRiQ8BQ27. Positions 509-555.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains fork-head DNA-binding domain.SAAS annotation

Phylogenomic databases

HOVERGENiHBG051657.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. TF_fork_head.
IPR011991. WHTH_DNA-bd_dom.
IPR015880. Znf_C2H2-like.
[Graphical view]
PfamiPF00250. Fork_head. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
SM00355. ZnF_C2H2. 1 hit.
[Graphical view]
PROSITEiPS50039. FORK_HEAD_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BQ27-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMQESATETI SNSSMNQNGM STLSSQLDAG SRDGRSSGDT SSEVSTVELL
60 70 80 90 100
HLQQQQALQA ARQLLLQQQT SGLKSPKSSE KQRPLQVPVS VAMMTPQVIT
110 120 130 140 150
PQQMQQILQQ QVLSPQQLQA LLQQQQAVML QQSKWFIQQQ LQEFYKKQQE
160 170 180 190 200
QLHLQLLQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQHP
210 220 230 240 250
GKQAKEQQQQ QQQQQLAAQQ LVFQQQLLQM QQLQQQQHLL SLQRQGLISI
260 270 280 290 300
PPGQAALPVQ SLPQAGLSPA EIQQLWKEVT GVHSMEDNGI KHGGLDLTTN
310 320 330 340 350
NSSSTTSSTT SKASPPITHH SIVNGQSSVL NARRDSSSHE ETGASHTLYG
360 370 380 390 400
HGVCKWPGCE SICEDFGQFL KHLNNEHALD DRSTAQCRVQ MQVVQQLEIQ
410 420 430 440 450
LSKERERLQA MMTHLHMRPS EPKPSPKPLN LVSSVTMSKN MLETSPQSLP
460 470 480 490 500
QTPTTPTAPV TPITQGPSVI TPASVPNVGA IRRRHSDKYN IPMSSEIAPN
510 520 530 540 550
YEFYKNADVR PPFTYATLIR QAIMESSDRQ LTLNEIYSWF TRTFAYFRRN
560 570 580
AATWKVTPKS SCSPSETQHS SFQIAPGAFI YMTQAD
Length:586
Mass (Da):66,107
Last modified:March 1, 2003 - v1
Checksum:iF75391FFBB2A98E3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK051668 mRNA. Translation: BAC34711.1.
UniGeneiMm.332919.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK051668 mRNA. Translation: BAC34711.1 .
UniGenei Mm.332919.

3D structure databases

ProteinModelPortali Q8BQ27.
SMRi Q8BQ27. Positions 509-555.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:2148705. Foxp2.

Phylogenomic databases

HOVERGENi HBG051657.

Miscellaneous databases

ChiTaRSi FOXP2. mouse.
SOURCEi Search...

Gene expression databases

Genevestigatori Q8BQ27.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR001766. TF_fork_head.
IPR011991. WHTH_DNA-bd_dom.
IPR015880. Znf_C2H2-like.
[Graphical view ]
Pfami PF00250. Fork_head. 1 hit.
[Graphical view ]
PRINTSi PR00053. FORKHEAD.
SMARTi SM00339. FH. 1 hit.
SM00355. ZnF_C2H2. 1 hit.
[Graphical view ]
PROSITEi PS50039. FORK_HEAD_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Spinal ganglionImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Spinal ganglionImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Spinal ganglionImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Spinal ganglionImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Spinal ganglionImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Spinal ganglionImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Spinal ganglionImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Spinal ganglionImported.

Entry informationi

Entry nameiQ8BQ27_MOUSE
AccessioniPrimary (citable) accession number: Q8BQ27
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 1, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)