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Q8BPV5

- Q8BPV5_MOUSE

UniProt

Q8BPV5 - Q8BPV5_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

App

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: MGI
    2. peptidase activator activity Source: Ensembl
    3. protein binding Source: MGI
    4. serine-type endopeptidase inhibitor activity Source: Ensembl

    GO - Biological processi

    1. adult locomotory behavior Source: MGI
    2. axon cargo transport Source: MGI
    3. axon midline choice point recognition Source: MGI
    4. axonogenesis Source: MGI
    5. cellular copper ion homeostasis Source: MGI
    6. cholesterol metabolic process Source: MGI
    7. collateral sprouting in absence of injury Source: MGI
    8. dendrite development Source: MGI
    9. endocytosis Source: MGI
    10. extracellular matrix organization Source: MGI
    11. forebrain development Source: MGI
    12. ionotropic glutamate receptor signaling pathway Source: MGI
    13. locomotory behavior Source: MGI
    14. mating behavior Source: MGI
    15. mRNA polyadenylation Source: MGI
    16. negative regulation of neuron differentiation Source: MGI
    17. neuromuscular process controlling balance Source: MGI
    18. neuron apoptotic process Source: MGI
    19. neuron projection development Source: MGI
    20. neuron remodeling Source: MGI
    21. positive regulation of G2/M transition of mitotic cell cycle Source: MGI
    22. positive regulation of mitotic cell cycle Source: MGI
    23. positive regulation of transcription from RNA polymerase II promoter Source: MGI
    24. protein homooligomerization Source: MGI
    25. protein phosphorylation Source: MGI
    26. regulation of epidermal growth factor-activated receptor activity Source: MGI
    27. regulation of gene expression Source: MGI
    28. regulation of multicellular organism growth Source: MGI
    29. regulation of protein binding Source: MGI
    30. regulation of synapse structure and activity Source: MGI
    31. regulation of translation Source: MGI
    32. response to oxidative stress Source: MGI
    33. smooth endoplasmic reticulum calcium ion homeostasis Source: MGI
    34. suckling behavior Source: MGI
    35. synaptic growth at neuromuscular junction Source: MGI
    36. visual learning Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:AppImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:88059. App.

    Subcellular locationi

    GO - Cellular componenti

    1. apical part of cell Source: MGI
    2. axon Source: MGI
    3. cell-cell junction Source: MGI
    4. cell surface Source: Ensembl
    5. ciliary rootlet Source: MGI
    6. cytoplasm Source: MGI
    7. cytoplasmic vesicle Source: MGI
    8. dendritic shaft Source: Ensembl
    9. dendritic spine Source: Ensembl
    10. ER to Golgi transport vesicle Source: MGI
    11. Golgi apparatus Source: MGI
    12. integral component of membrane Source: MGI
    13. membrane Source: MGI
    14. neuromuscular junction Source: MGI
    15. neuron projection Source: MGI
    16. perinuclear region of cytoplasm Source: MGI
    17. plasma membrane Source: MGI
    18. receptor complex Source: MGI
    19. spindle midzone Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiQ8BPV5.
    BgeeiQ8BPV5.
    GenevestigatoriQ8BPV5.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8BPV5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG000051.
    InParanoidiQ8BPV5.

    Family and domain databases

    Gene3Di4.10.230.10. 1 hit.
    InterProiIPR008155. Amyloid_glyco.
    IPR013803. Amyloid_glyco_Abeta.
    IPR019745. Amyloid_glyco_intracell_CS.
    IPR028866. APP.
    IPR019543. APP_amyloid_C.
    [Graphical view]
    PANTHERiPTHR23103:SF7. PTHR23103:SF7. 1 hit.
    PfamiPF10515. APP_amyloid. 1 hit.
    PF03494. Beta-APP. 1 hit.
    [Graphical view]
    PRINTSiPR00203. AMYLOIDA4.
    PR00204. BETAAMYLOID.
    PROSITEiPS00320. A4_INTRA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q8BPV5-1 [UniParc]FASTAAdd to Basket

    « Hide

    AVAEEIQDEV DELLQKEQNY SDDVLANMIS EPRISYGNDA LMPSLTETKT    50
    TVELLPVNGE FSLDDLQPWH PFGVDSVPAN TENEVEPVDA RPAADRGLTT 100
    RPGSGLTNIK TEEISEVKMD AEFGHDSGFE VRHQKLVFFA EDVGSNKGAI 150
    IGLMVGGVVI ATVIVITLVM LKKKQYTSIH HGVVEVDAAV TPEERHLSKM 200
    QQNGYENPTY KFFEQMQN 218
    Length:218
    Mass (Da):24,118
    Last modified:March 1, 2003 - v1
    Checksum:i95B55AFDAE1D0EF5
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK052448 mRNA. Translation: BAC34997.1.
    UniGeneiMm.277585.
    Mm.489029.
    Mm.490986.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK052448 mRNA. Translation: BAC34997.1 .
    UniGenei Mm.277585.
    Mm.489029.
    Mm.490986.

    3D structure databases

    ProteinModelPortali Q8BPV5.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:88059. App.

    Phylogenomic databases

    HOVERGENi HBG000051.
    InParanoidi Q8BPV5.

    Miscellaneous databases

    ChiTaRSi app. mouse.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8BPV5.
    Bgeei Q8BPV5.
    Genevestigatori Q8BPV5.

    Family and domain databases

    Gene3Di 4.10.230.10. 1 hit.
    InterProi IPR008155. Amyloid_glyco.
    IPR013803. Amyloid_glyco_Abeta.
    IPR019745. Amyloid_glyco_intracell_CS.
    IPR028866. APP.
    IPR019543. APP_amyloid_C.
    [Graphical view ]
    PANTHERi PTHR23103:SF7. PTHR23103:SF7. 1 hit.
    Pfami PF10515. APP_amyloid. 1 hit.
    PF03494. Beta-APP. 1 hit.
    [Graphical view ]
    PRINTSi PR00203. AMYLOIDA4.
    PR00204. BETAAMYLOID.
    PROSITEi PS00320. A4_INTRA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    5. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported.

    Entry informationi

    Entry nameiQ8BPV5_MOUSE
    AccessioniPrimary (citable) accession number: Q8BPV5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)