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Q8BPV5 (Q8BPV5_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:App MGI 88059
OrganismMus musculus (Mouse) EMBL BAC34997.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length218 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Gene Ontology (GO)
   Biological_processadult locomotory behavior

Inferred from mutant phenotype PubMed 10188929PubMed 7758106PubMed 8001115PubMed 9754878. Source: MGI

axon cargo transport

Inferred from mutant phenotype PubMed 11740561. Source: MGI

axon midline choice point recognition

Inferred from mutant phenotype PubMed 8001115. Source: MGI

axonogenesis

Inferred from mutant phenotype PubMed 9390996. Source: MGI

cellular copper ion homeostasis

Inferred from mutant phenotype PubMed 10526140. Source: MGI

cholesterol metabolic process

Inferred from mutant phenotype PubMed 17920016. Source: MGI

collateral sprouting in absence of injury

Inferred from genetic interaction PubMed 15689559. Source: MGI

dendrite development

Inferred from mutant phenotype PubMed 10188929PubMed 9390996. Source: MGI

endocytosis

Inferred from mutant phenotype PubMed 16025111. Source: MGI

extracellular matrix organization

Inferred from genetic interaction PubMed 15385965. Source: MGI

forebrain development

Inferred from mutant phenotype PubMed 10200318PubMed 8001115. Source: MGI

ionotropic glutamate receptor signaling pathway

Inferred from mutant phenotype PubMed 16025111. Source: MGI

locomotory behavior

Inferred from genetic interaction PubMed 9461064. Source: MGI

mRNA polyadenylation

Inferred from direct assay PubMed 16314516. Source: MGI

mating behavior

Inferred from genetic interaction PubMed 9461064. Source: MGI

negative regulation of neuron differentiation

Inferred from direct assay PubMed 18278038. Source: MGI

neuromuscular process controlling balance

Inferred from genetic interaction PubMed 9461064. Source: MGI

neuron apoptotic process

Inferred from genetic interaction PubMed 16478525. Source: MGI

neuron projection development

Inferred from direct assay PubMed 8083748. Source: MGI

neuron remodeling

Inferred from mutant phenotype PubMed 10219973. Source: MGI

positive regulation of G2/M transition of mitotic cell cycle

Inferred from mutant phenotype PubMed 15561424. Source: MGI

positive regulation of mitotic cell cycle

Inferred from mutant phenotype PubMed 15561424. Source: MGI

positive regulation of transcription from RNA polymerase II promoter

Inferred from direct assay PubMed 15944124. Source: MGI

protein phosphorylation

Inferred from mutant phenotype PubMed 16025111. Source: MGI

regulation of epidermal growth factor-activated receptor activity

Inferred from genetic interaction PubMed 17556541. Source: MGI

regulation of gene expression

Inferred from direct assay PubMed 12074840. Source: MGI

regulation of multicellular organism growth

Inferred from mutant phenotype PubMed 9754878. Source: MGI

regulation of protein binding

Inferred from mutant phenotype PubMed 17920016. Source: MGI

regulation of synapse structure and activity

Inferred from mutant phenotype PubMed 10219973. Source: MGI

regulation of translation

Inferred from direct assay PubMed 16314516. Source: MGI

response to oxidative stress

Inferred from genetic interaction PubMed 16478525. Source: MGI

smooth endoplasmic reticulum calcium ion homeostasis

Inferred from genetic interaction PubMed 12431992. Source: MGI

suckling behavior

Inferred from genetic interaction PubMed 9461064. Source: MGI

synaptic growth at neuromuscular junction

Inferred from genetic interaction PubMed 15689559. Source: MGI

visual learning

Inferred from mutant phenotype PubMed 10338291. Source: MGI

   Cellular_componentER to Golgi transport vesicle

Inferred from direct assay PubMed 19966784. Source: MGI

Golgi apparatus

Inferred from direct assay PubMed 16018997. Source: MGI

apical part of cell

Inferred from direct assay PubMed 15561424. Source: MGI

axon

Inferred from direct assay PubMed 11740561PubMed 15745965. Source: MGI

cell surface

Inferred from electronic annotation. Source: Ensembl

cell-cell junction

Inferred from direct assay PubMed 23793062. Source: MGI

ciliary rootlet

Inferred from direct assay PubMed 16018997. Source: MGI

cytoplasm

Inferred from direct assay PubMed 10845772. Source: MGI

cytoplasmic vesicle

Inferred from direct assay PubMed 11740561PubMed 15745965. Source: MGI

dendritic shaft

Inferred from electronic annotation. Source: Ensembl

dendritic spine

Inferred from electronic annotation. Source: Ensembl

integral component of membrane

Inferred from direct assay PubMed 12927782. Source: MGI

membrane

Inferred from direct assay PubMed 10845772PubMed 12927782PubMed 15886206PubMed 9535056. Source: MGI

neuromuscular junction

Inferred from direct assay PubMed 10845772. Source: MGI

neuron projection

Inferred from direct assay PubMed 16301330. Source: MGI

perinuclear region of cytoplasm

Inferred from direct assay PubMed 8207383. Source: MGI

plasma membrane

Inferred from direct assay PubMed 15009636. Source: MGI

receptor complex

Inferred from sequence orthology PubMed 23382219. Source: MGI

spindle midzone

Inferred from direct assay PubMed 15561424. Source: MGI

   Molecular_functionDNA binding

Inferred from direct assay PubMed 15944124. Source: MGI

peptidase activator activity

Inferred from electronic annotation. Source: Ensembl

protein binding

Inferred from physical interaction PubMed 16314516PubMed 18278038PubMed 20497468PubMed 21795536. Source: MGI

serine-type endopeptidase inhibitor activity

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL BAC34997.1

Sequences

Sequence LengthMass (Da)Tools
Q8BPV5 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 95B55AFDAE1D0EF5

FASTA21824,118
        10         20         30         40         50         60 
AVAEEIQDEV DELLQKEQNY SDDVLANMIS EPRISYGNDA LMPSLTETKT TVELLPVNGE 

        70         80         90        100        110        120 
FSLDDLQPWH PFGVDSVPAN TENEVEPVDA RPAADRGLTT RPGSGLTNIK TEEISEVKMD 

       130        140        150        160        170        180 
AEFGHDSGFE VRHQKLVFFA EDVGSNKGAI IGLMVGGVVI ATVIVITLVM LKKKQYTSIH 

       190        200        210 
HGVVEVDAAV TPEERHLSKM QQNGYENPTY KFFEQMQN 

« Hide

References

[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC34997.1.
Tissue: Lung EMBL BAC34997.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC34997.1.
Tissue: Lung EMBL BAC34997.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC34997.1.
Tissue: Lung EMBL BAC34997.1.
[4]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC34997.1.
Tissue: Lung EMBL BAC34997.1.
[5]Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P., Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W., Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T., Hori F., Imotani K. expand/collapse author list , Ishii Y., Itoh M., Kagawa I., Kasukawa T., Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M., Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y., Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H., Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M., Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T., Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.
Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC34997.1.
Tissue: Lung EMBL BAC34997.1.
[6]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC34997.1.
Tissue: Lung EMBL BAC34997.1.
[7]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC34997.1.
Tissue: Lung EMBL BAC34997.1.
[8]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC34997.1.
Tissue: Lung EMBL BAC34997.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK052448 mRNA. Translation: BAC34997.1.
UniGeneMm.277585.
Mm.489029.
Mm.490986.

3D structure databases

ProteinModelPortalQ8BPV5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:88059. App.

Phylogenomic databases

HOVERGENHBG000051.
InParanoidQ8BPV5.

Gene expression databases

ArrayExpressQ8BPV5.
BgeeQ8BPV5.
GenevestigatorQ8BPV5.

Family and domain databases

Gene3D4.10.230.10. 1 hit.
InterProIPR008155. Amyloid_glyco.
IPR013803. Amyloid_glyco_Abeta.
IPR019745. Amyloid_glyco_intracell_CS.
IPR028866. APP.
IPR019543. APP_amyloid_C.
[Graphical view]
PANTHERPTHR23103:SF7. PTHR23103:SF7. 1 hit.
PfamPF10515. APP_amyloid. 1 hit.
PF03494. Beta-APP. 1 hit.
[Graphical view]
PRINTSPR00203. AMYLOIDA4.
PR00204. BETAAMYLOID.
PROSITEPS00320. A4_INTRA. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSapp. mouse.
SOURCESearch...

Entry information

Entry nameQ8BPV5_MOUSE
AccessionPrimary (citable) accession number: Q8BPV5
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: June 11, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)