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Protein
Submitted name:

Putative uncharacterized protein

Gene

App

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:AppImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88059. App.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei149 – 171HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ8BPV5.
PeptideAtlasiQ8BPV5.

Expressioni

Gene expression databases

BgeeiENSMUSG00000022892.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000005406.

Structurei

3D structure databases

ProteinModelPortaliQ8BPV5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini125 – 161Beta-APPInterPro annotationAdd BLAST37
Domaini164 – 214APP_amyloidInterPro annotationAdd BLAST51

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3540. Eukaryota.
ENOG410ZW2A. LUCA.
HOVERGENiHBG000051.

Family and domain databases

Gene3Di4.10.230.10. 1 hit.
InterProiIPR008155. Amyloid_glyco.
IPR013803. Amyloid_glyco_Abeta.
IPR019745. Amyloid_glyco_intracell_CS.
IPR028866. APP.
IPR019543. APP_amyloid_C.
[Graphical view]
PANTHERiPTHR23103:SF7. PTHR23103:SF7. 1 hit.
PfamiPF10515. APP_amyloid. 1 hit.
PF03494. Beta-APP. 1 hit.
[Graphical view]
PRINTSiPR00203. AMYLOIDA4.
PR00204. BETAAMYLOID.
PROSITEiPS00320. A4_INTRA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8BPV5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
AVAEEIQDEV DELLQKEQNY SDDVLANMIS EPRISYGNDA LMPSLTETKT
60 70 80 90 100
TVELLPVNGE FSLDDLQPWH PFGVDSVPAN TENEVEPVDA RPAADRGLTT
110 120 130 140 150
RPGSGLTNIK TEEISEVKMD AEFGHDSGFE VRHQKLVFFA EDVGSNKGAI
160 170 180 190 200
IGLMVGGVVI ATVIVITLVM LKKKQYTSIH HGVVEVDAAV TPEERHLSKM
210
QQNGYENPTY KFFEQMQN
Length:218
Mass (Da):24,118
Last modified:March 1, 2003 - v1
Checksum:i95B55AFDAE1D0EF5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK052448 mRNA. Translation: BAC34997.1.
UniGeneiMm.277585.
Mm.489029.
Mm.490986.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK052448 mRNA. Translation: BAC34997.1.
UniGeneiMm.277585.
Mm.489029.
Mm.490986.

3D structure databases

ProteinModelPortaliQ8BPV5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000005406.

Proteomic databases

PaxDbiQ8BPV5.
PeptideAtlasiQ8BPV5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:88059. App.

Phylogenomic databases

eggNOGiKOG3540. Eukaryota.
ENOG410ZW2A. LUCA.
HOVERGENiHBG000051.

Miscellaneous databases

ChiTaRSiApp. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000022892.

Family and domain databases

Gene3Di4.10.230.10. 1 hit.
InterProiIPR008155. Amyloid_glyco.
IPR013803. Amyloid_glyco_Abeta.
IPR019745. Amyloid_glyco_intracell_CS.
IPR028866. APP.
IPR019543. APP_amyloid_C.
[Graphical view]
PANTHERiPTHR23103:SF7. PTHR23103:SF7. 1 hit.
PfamiPF10515. APP_amyloid. 1 hit.
PF03494. Beta-APP. 1 hit.
[Graphical view]
PRINTSiPR00203. AMYLOIDA4.
PR00204. BETAAMYLOID.
PROSITEiPS00320. A4_INTRA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8BPV5_MOUSE
AccessioniPrimary (citable) accession number: Q8BPV5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 7, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.