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Protein
Submitted name:

Uncharacterized protein

Gene

App

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:AppImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88059. App.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei149 – 171HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ8BPV5.
PeptideAtlasiQ8BPV5.

Structurei

3D structure databases

ProteinModelPortaliQ8BPV5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini125 – 161Beta-APPInterPro annotationAdd BLAST37
Domaini164 – 214APP_amyloidInterPro annotationAdd BLAST51

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3540. Eukaryota.
ENOG410ZW2A. LUCA.
HOVERGENiHBG000051.

Family and domain databases

Gene3Di4.10.230.10. 1 hit.
InterProiView protein in InterPro
IPR008155. Amyloid_glyco.
IPR013803. Amyloid_glyco_Abeta.
IPR019745. Amyloid_glyco_intracell_CS.
IPR028866. APP.
IPR019543. APP_amyloid_C.
PANTHERiPTHR23103:SF17. PTHR23103:SF17. 1 hit.
PfamiView protein in Pfam
PF10515. APP_amyloid. 1 hit.
PF03494. Beta-APP. 1 hit.
PRINTSiPR00203. AMYLOIDA4.
PR00204. BETAAMYLOID.
PROSITEiView protein in PROSITE
PS00320. A4_INTRA. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q8BPV5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
AVAEEIQDEV DELLQKEQNY SDDVLANMIS EPRISYGNDA LMPSLTETKT
60 70 80 90 100
TVELLPVNGE FSLDDLQPWH PFGVDSVPAN TENEVEPVDA RPAADRGLTT
110 120 130 140 150
RPGSGLTNIK TEEISEVKMD AEFGHDSGFE VRHQKLVFFA EDVGSNKGAI
160 170 180 190 200
IGLMVGGVVI ATVIVITLVM LKKKQYTSIH HGVVEVDAAV TPEERHLSKM
210
QQNGYENPTY KFFEQMQN
Length:218
Mass (Da):24,118
Last modified:March 1, 2003 - v1
Checksum:i95B55AFDAE1D0EF5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK052448 mRNA. Translation: BAC34997.1.
UniGeneiMm.277585.
Mm.489029.
Mm.490986.

Similar proteinsi

Entry informationi

Entry nameiQ8BPV5_MOUSE
AccessioniPrimary (citable) accession number: Q8BPV5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: August 30, 2017
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)