Q8BPV5 (Q8BPV5_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein EMBL BAC34997.1

Gene names

Name:

App MGI 88059

Organism

Mus musculus (Mouse) EMBL BAC34997.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	218 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	G2 phase of mitotic cell cycle Inferred from mutant phenotype PubMed 15561424. Source: MGI adult locomotory behavior Inferred from mutant phenotype PubMed 10188929PubMed 7758106PubMed 8001115PubMed 9754878. Source: MGI axon cargo transport Inferred from mutant phenotype PubMed 11740561. Source: MGI axon midline choice point recognition Inferred from mutant phenotype PubMed 8001115. Source: MGI cellular copper ion homeostasis Inferred from mutant phenotype PubMed 10526140. Source: MGI cholesterol metabolic process Inferred from mutant phenotype PubMed 17920016. Source: MGI collateral sprouting in absence of injury Inferred from genetic interaction PubMed 15689559. Source: MGI dendrite development Inferred from mutant phenotype PubMed 10188929PubMed 9390996. Source: MGI endocytosis Inferred from mutant phenotype PubMed 16025111. Source: MGI extracellular matrix organization Inferred from genetic interaction PubMed 15385965. Source: MGI forebrain development Inferred from mutant phenotype PubMed 10200318PubMed 8001115. Source: MGI induction of apoptosis Inferred from electronic annotation. Source: Compara ionotropic glutamate receptor signaling pathway Inferred from mutant phenotype PubMed 16025111. Source: MGI mRNA polyadenylation Inferred from direct assay PubMed 16314516. Source: MGI mating behavior Inferred from genetic interaction PubMed 9461064. Source: MGI negative regulation of neuron differentiation Inferred from direct assay PubMed 18278038. Source: MGI neuromuscular process controlling balance Inferred from genetic interaction PubMed 9461064. Source: MGI neuron apoptotic process Inferred from genetic interaction PubMed 16478525. Source: MGI neuron remodeling Inferred from mutant phenotype PubMed 10219973. Source: MGI positive regulation of mitotic cell cycle Inferred from mutant phenotype PubMed 15561424. Source: MGI positive regulation of transcription from RNA polymerase II promoter Inferred from direct assay PubMed 15944124. Source: MGI protein phosphorylation Inferred from mutant phenotype PubMed 16025111. Source: MGI regulation of epidermal growth factor-activated receptor activity Inferred from genetic interaction PubMed 17556541. Source: MGI regulation of multicellular organism growth Inferred from mutant phenotype PubMed 9754878. Source: MGI regulation of protein binding Inferred from mutant phenotype PubMed 17920016. Source: MGI regulation of synapse structure and activity Inferred from mutant phenotype PubMed 10219973. Source: MGI regulation of translation Inferred from direct assay PubMed 16314516. Source: MGI response to oxidative stress Inferred from genetic interaction PubMed 16478525. Source: MGI smooth endoplasmic reticulum calcium ion homeostasis Inferred from genetic interaction PubMed 12431992. Source: MGI suckling behavior Inferred from genetic interaction PubMed 9461064. Source: MGI synaptic growth at neuromuscular junction Inferred from genetic interaction PubMed 15689559. Source: MGI visual learning Inferred from mutant phenotype PubMed 10338291. Source: MGI
Cellular_component	Golgi apparatus Inferred from direct assay PubMed 16018997. Source: MGI apical part of cell Inferred from direct assay PubMed 15561424. Source: MGI axon Inferred from direct assay PubMed 11740561PubMed 15745965. Source: MGI cell surface Inferred from electronic annotation. Source: Compara ciliary rootlet Inferred from direct assay PubMed 16018997. Source: MGI cytoplasmic vesicle Inferred from direct assay PubMed 11740561PubMed 15745965. Source: MGI dendritic shaft Inferred from electronic annotation. Source: Compara dendritic spine Inferred from electronic annotation. Source: Compara integral to membrane Inferred from direct assay PubMed 12927782. Source: MGI neuromuscular junction Inferred from direct assay PubMed 10845772. Source: MGI perinuclear region of cytoplasm Inferred from direct assay PubMed 8207383. Source: MGI plasma membrane Inferred from direct assay PubMed 15009636. Source: MGI spindle midzone Inferred from direct assay PubMed 15561424. Source: MGI
Molecular_function	DNA binding Inferred from direct assay PubMed 15944124. Source: MGI peptidase activator activity Inferred from electronic annotation. Source: Compara serine-type endopeptidase inhibitor activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAC34997.1

Sequences

	Sequence		Length	Mass (Da)
	Q8BPV5 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 95B55AFDAE1D0EF5	FASTA	218	24,118
	10 20 30 40 50 60 AVAEEIQDEV DELLQKEQNY SDDVLANMIS EPRISYGNDA LMPSLTETKT TVELLPVNGE 70 80 90 100 110 120 FSLDDLQPWH PFGVDSVPAN TENEVEPVDA RPAADRGLTT RPGSGLTNIK TEEISEVKMD 130 140 150 160 170 180 AEFGHDSGFE VRHQKLVFFA EDVGSNKGAI IGLMVGGVVI ATVIVITLVM LKKKQYTSIH 190 200 210 HGVVEVDAAV TPEERHLSKM QQNGYENPTY KFFEQMQN

References

[1]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC34997.1. Tissue: Lung EMBL BAC34997.1.
[2]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC34997.1. Tissue: Lung EMBL BAC34997.1.
[3]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC34997.1. Tissue: Lung EMBL BAC34997.1.
[4]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC34997.1. Tissue: Lung EMBL BAC34997.1.
[5]	Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P., Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W., Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T., Hori F., Imotani K. , Ishii Y., Itoh M., Kagawa I., Kasukawa T., Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M., Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y., Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H., Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M., Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T., Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y. Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC34997.1. Tissue: Lung EMBL BAC34997.1.
[6]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC34997.1. Tissue: Lung EMBL BAC34997.1.
[7]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC34997.1. Tissue: Lung EMBL BAC34997.1.
[8]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC34997.1. Tissue: Lung EMBL BAC34997.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK052448 mRNA. Translation: BAC34997.1.
IPI	IPI00323079.
UniGene	Mm.277585. Mm.489029. Mm.490986.
3D structure databases
HSSP	HSSP built from PDB template 1NMJ based on UniProtKB P08592.
ProteinModelPortal	Q8BPV5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8BPV5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
MGI	MGI:88059. App.
Phylogenomic databases
HOVERGEN	HBG000051.
InParanoid	Q8BPV5.
Gene expression databases
ArrayExpress	Q8BPV5.
Bgee	Q8BPV5.
Genevestigator	Q8BPV5.
Family and domain databases
Gene3D	4.10.230.10. 1 hit.
InterPro	IPR008155. Amyloid_glyco. IPR013803. Amyloid_glyco_Abeta. IPR019745. Amyloid_glyco_intracell_CS. IPR019543. APP_amyloid_C. [Graphical view]
Pfam	PF10515. APP_amyloid. 1 hit. PF03494. Beta-APP. 1 hit. [Graphical view]
PRINTS	PR00203. AMYLOIDA4. PR00204. BETAAMYLOID.
PROSITE	PS00320. A4_INTRA. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	app. mouse.
SOURCE	Search...

Entry information

Entry name

Q8BPV5_MOUSE

Accession

Primary (citable) accession number: Q8BPV5

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	April 3, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)