Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Integral membrane protein GPR180

Gene

Gpr180

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Integral membrane protein GPR180
Gene namesi
Name:Gpr180
ORF Names:MNCb-3029
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1930949. Gpr180.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei174 – 19421HelicalSequence analysisAdd
BLAST
Transmembranei206 – 22621HelicalSequence analysisAdd
BLAST
Transmembranei250 – 27021HelicalSequence analysisAdd
BLAST
Transmembranei285 – 30521HelicalSequence analysisAdd
BLAST
Transmembranei322 – 34221HelicalSequence analysisAdd
BLAST
Transmembranei361 – 38121HelicalSequence analysisAdd
BLAST
Transmembranei390 – 41021HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence analysisAdd
BLAST
Chaini24 – 441418Integral membrane protein GPR180PRO_0000239663Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi111 – 1111N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

EPDiQ8BPS4.
MaxQBiQ8BPS4.
PaxDbiQ8BPS4.
PRIDEiQ8BPS4.

PTM databases

iPTMnetiQ8BPS4.

Expressioni

Gene expression databases

BgeeiQ8BPS4.
CleanExiMM_GPR180.
GenevisibleiQ8BPS4. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022728.

Structurei

3D structure databases

ProteinModelPortaliQ8BPS4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4290. Eukaryota.
ENOG410XRGS. LUCA.
GeneTreeiENSGT00730000111205.
HOGENOMiHOG000013021.
HOVERGENiHBG056171.
InParanoidiQ8BPS4.
OMAiPGLACIS.
OrthoDBiEOG793B7H.
PhylomeDBiQ8BPS4.
TreeFamiTF314975.

Family and domain databases

InterProiIPR019336. Intimal_thickness-rel_rcpt.
[Graphical view]
PfamiPF10192. GpcrRhopsn4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8BPS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGLRLLAVA LTCSCWWPQG GQGKTLRGSF SSAAARDAQG QSIGHFEFHG
60 70 80 90 100
DHALLCVRIN NVAVAVGKEA KLYLFQAQEW LKLLESSPGY SCSERLARAQ
110 120 130 140 150
LTVTVTQTEH NLTVSQLPAP QTWRVFYADK FTCRDDSESP QGEEIPFEMV
160 170 180 190 200
LLNPDAEGNP LDHFSARESG LHEFFFLLVL VYFVTACIYA QSLWQAMKKG
210 220 230 240 250
GPMHTILKVL TTALLLQAAS ALANYIHLSR YSRDGLGVPL IGSLAEVFDI
260 270 280 290 300
ASQIQMLYLL LSLCMGWTIV RMKKSQSRPL QWDSTPASTG IAVFIVITQS
310 320 330 340 350
ILLLWEQFED TSHHSAHSHR SLAGLLLIVL RICLALSLGC GLYQVITVER
360 370 380 390 400
SALKREFYIT FAKGCILWFL CQPALACIAV AFNDYQRDKL ITVGVILCQA
410 420 430 440
VAMVILYRLF LSHSLYWEVS SLSSVTLPLT ISSAHRGRPH F
Length:441
Mass (Da):48,975
Last modified:March 1, 2003 - v1
Checksum:i4FEFB71F60063ED9
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti420 – 4201S → P in BAA95030 (Ref. 1) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB041545 mRNA. Translation: BAA95030.1.
AK053422 mRNA. Translation: BAC35382.1.
AK169908 mRNA. Translation: BAE41450.1.
BC069981 mRNA. Translation: AAH69981.1.
CCDSiCCDS27333.1.
RefSeqiNP_067409.2. NM_021434.5.
UniGeneiMm.275411.

Genome annotation databases

EnsembliENSMUST00000022728; ENSMUSP00000022728; ENSMUSG00000022131.
GeneIDi58245.
KEGGimmu:58245.
UCSCiuc007uyq.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB041545 mRNA. Translation: BAA95030.1.
AK053422 mRNA. Translation: BAC35382.1.
AK169908 mRNA. Translation: BAE41450.1.
BC069981 mRNA. Translation: AAH69981.1.
CCDSiCCDS27333.1.
RefSeqiNP_067409.2. NM_021434.5.
UniGeneiMm.275411.

3D structure databases

ProteinModelPortaliQ8BPS4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022728.

PTM databases

iPTMnetiQ8BPS4.

Proteomic databases

EPDiQ8BPS4.
MaxQBiQ8BPS4.
PaxDbiQ8BPS4.
PRIDEiQ8BPS4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000022728; ENSMUSP00000022728; ENSMUSG00000022131.
GeneIDi58245.
KEGGimmu:58245.
UCSCiuc007uyq.2. mouse.

Organism-specific databases

CTDi160897.
MGIiMGI:1930949. Gpr180.

Phylogenomic databases

eggNOGiKOG4290. Eukaryota.
ENOG410XRGS. LUCA.
GeneTreeiENSGT00730000111205.
HOGENOMiHOG000013021.
HOVERGENiHBG056171.
InParanoidiQ8BPS4.
OMAiPGLACIS.
OrthoDBiEOG793B7H.
PhylomeDBiQ8BPS4.
TreeFamiTF314975.

Miscellaneous databases

ChiTaRSiGpr180. mouse.
PROiQ8BPS4.
SOURCEiSearch...

Gene expression databases

BgeeiQ8BPS4.
CleanExiMM_GPR180.
GenevisibleiQ8BPS4. MM.

Family and domain databases

InterProiIPR019336. Intimal_thickness-rel_rcpt.
[Graphical view]
PfamiPF10192. GpcrRhopsn4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Isolation of full-length cDNA clones from mouse brain cDNA library made by oligo-capping method."
    Osada N., Kusuda J., Tanuma R., Ito A., Hirata M., Sugano S., Hashimoto K.
    Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Brain.
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J and NOD.
    Tissue: Eye.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Embryo.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Kidney, Liver, Lung, Pancreas, Spleen and Testis.

Entry informationi

Entry nameiGP180_MOUSE
AccessioniPrimary (citable) accession number: Q8BPS4
Secondary accession number(s): Q9JJG1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: March 1, 2003
Last modified: June 8, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.