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Protein
Submitted name:

Transcription factor AP-2, alpha, isoform CRA_c

Gene

Tfap2a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

ReactomeiR-MMU-8864260. Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors.
R-MMU-8866904. Negative regulation of activity of TFAP2 (AP-2) family transcription factors.
R-MMU-8866907. Activation of the TFAP2 (AP-2) family of transcription factors.

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor AP-2, alpha, isoform CRA_cImported
Submitted name:
Transcription factor AP-2-alphaImported
Gene namesi
Name:Tfap2aImported
Synonyms:Tcfap2aImported
ORF Names:mCG_5075Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:104671. Tfap2a.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000021359.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini205 – 399TF_AP-2InterPro annotationAdd BLAST195

Phylogenomic databases

eggNOGiKOG3811. Eukaryota.
ENOG410XR9E. LUCA.
GeneTreeiENSGT00550000074577.
HOVERGENiHBG002455.
KOiK09176.

Family and domain databases

InterProiView protein in InterPro
IPR004979. TF_AP2.
IPR008121. TF_AP2_alpha_N.
IPR013854. TF_AP2_C.
PANTHERiPTHR10812. PTHR10812. 1 hit.
PTHR10812:SF8. PTHR10812:SF8. 1 hit.
PfamiView protein in Pfam
PF03299. TF_AP-2. 1 hit.
PRINTSiPR01749. AP2ATNSCPFCT.
PR01748. AP2TNSCPFCT.

Sequencei

Sequence statusi: Complete.

Q8BPN4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVHSFSAMD RHDGTSNGTA RLPQLGTVGQ SPYTSAPPLS HTPNADFQPP
60 70 80 90 100
YFPPPYQPIY PQSQDPYSHV NDPYSLNPLH AQPQPQHPGW PGQRQSQESG
110 120 130 140 150
LLHTHRGLPH QLSGLDPRRD YRRHEDLLHG PHGLGSGLGD LPIHSLPHAI
160 170 180 190 200
EDVPHVEDPG INIPDQTVIK KGPVSLSKSN SNAVSAIPIN KDNLFGGVVN
210 220 230 240 250
PNEVFCSVPG RLSLLSSTSK YKVTVAEVQR RLSPPECLNA SLLGGVLRRA
260 270 280 290 300
KSKNGGRSLR EKLDKIGLNL PAGRRKAANV TLLTSLVEGE AVHLARDFGY
310 320 330 340 350
VCETEFPAKA VAEFLNRQHS DPNEQVARKN MLLATKQICK EFTDLLAQDR
360 370 380 390 400
SPLGNSRPNP ILEPGIQSCL THFNLISHGF GSPAVCAAVT ALQNYLTEAL
410 420 430
KAMDKMYLSN NPNSHTDNSA KSSDKEEKHR K
Length:431
Mass (Da):47,078
Last modified:March 1, 2003 - v1
Checksum:i17CCBD6197FB56FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123834 Genomic DNA. No translation available.
AC159205 Genomic DNA. No translation available.
AK053704 mRNA. Translation: BAC35484.1.
CH466546 Genomic DNA. Translation: EDL40952.1.
RefSeqiNP_001116420.1. NM_001122948.2.
NP_001288603.1. NM_001301674.1.
NP_035677.2. NM_011547.4.
UniGeneiMm.487150.
Mm.85544.

Genome annotation databases

EnsembliENSMUST00000021787; ENSMUSP00000021787; ENSMUSG00000021359.
GeneIDi21418.
KEGGimmu:21418.
UCSCiuc007qee.3. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ8BPN4_MOUSE
AccessioniPrimary (citable) accession number: Q8BPN4
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 25, 2017
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported