Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Putative uncharacterized protein

Gene

Igfbp3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • negative regulation of cell proliferation Source: MGI
  • negative regulation of protein phosphorylation Source: MGI
  • negative regulation of smooth muscle cell migration Source: MGI
  • negative regulation of smooth muscle cell proliferation Source: MGI
  • positive regulation of apoptotic process Source: MGI
  • positive regulation of catalytic activity Source: MGI
  • positive regulation of insulin-like growth factor receptor signaling pathway Source: MGI
  • positive regulation of MAPK cascade Source: MGI
  • positive regulation of myoblast differentiation Source: MGI
  • protein phosphorylation Source: MGI
  • regulation of cell growth Source: MGI
  • regulation of glucose metabolic process Source: MGI
  • regulation of growth Source: MGI
  • type B pancreatic cell proliferation Source: MGI
Complete GO annotation...

Protein family/group databases

MEROPSiI31.952.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Igfbp3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96438. Igfbp3.

Subcellular locationi

GO - Cellular componenti

  • extracellular exosome Source: MGI
  • extracellular space Source: MGI
  • nucleus Source: MGI
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000020702.

Structurei

3D structure databases

ProteinModelPortaliQ8BP94.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG002631.

Family and domain databases

Gene3Di4.10.800.10. 1 hit.
InterProiIPR012211. IGFBP-3.
IPR009168. IGFBP1-6.
IPR022321. IGFBP_1-6_chordata.
IPR000716. Thyroglobulin_1.
[Graphical view]
PANTHERiPTHR11551. PTHR11551. 1 hit.
PTHR11551:SF3. PTHR11551:SF3. 1 hit.
PfamiPF00086. Thyroglobulin_1. 1 hit.
[Graphical view]
PRINTSiPR01976. IGFBPFAMILY.
PR01979. IGFBPFAMILY3.
SMARTiSM00211. TY. 1 hit.
[Graphical view]
SUPFAMiSSF57610. SSF57610. 1 hit.
PROSITEiPS00484. THYROGLOBULIN_1_1. 1 hit.
PS51162. THYROGLOBULIN_1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BP94-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGRGFCANA SAAGSLSTYL PSQPAPGNIS ESEEEHNAGS VESQVVPSTH
60 70 80 90 100
RVTDSKFHPL HAKMDVIKKG HARDSQRYKV DYESQSTDTQ NFSSESKRET
110 120 130 140 150
EYGPCRREME DTLNHLKFLN VLSPRGVHIP NCDKKGFYKK KQCRPSKGRK
160 170 180
RGFCWCVDKY GQPLPGYDTK GKDDVHCLSV QSQ
Length:183
Mass (Da):20,526
Last modified:October 11, 2005 - v2
Checksum:iAE6C18D441E0A71F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK077477 mRNA. Translation: BAC36819.2.
UniGeneiMm.29254.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK077477 mRNA. Translation: BAC36819.2.
UniGeneiMm.29254.

3D structure databases

ProteinModelPortaliQ8BP94.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000020702.

Protein family/group databases

MEROPSiI31.952.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:96438. Igfbp3.

Phylogenomic databases

HOVERGENiHBG002631.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

Gene3Di4.10.800.10. 1 hit.
InterProiIPR012211. IGFBP-3.
IPR009168. IGFBP1-6.
IPR022321. IGFBP_1-6_chordata.
IPR000716. Thyroglobulin_1.
[Graphical view]
PANTHERiPTHR11551. PTHR11551. 1 hit.
PTHR11551:SF3. PTHR11551:SF3. 1 hit.
PfamiPF00086. Thyroglobulin_1. 1 hit.
[Graphical view]
PRINTSiPR01976. IGFBPFAMILY.
PR01979. IGFBPFAMILY3.
SMARTiSM00211. TY. 1 hit.
[Graphical view]
SUPFAMiSSF57610. SSF57610. 1 hit.
PROSITEiPS00484. THYROGLOBULIN_1_1. 1 hit.
PS51162. THYROGLOBULIN_1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.

Entry informationi

Entry nameiQ8BP94_MOUSE
AccessioniPrimary (citable) accession number: Q8BP94
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: October 11, 2005
Last modified: June 24, 2015
This is version 79 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.