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Protein

Cytochrome c heme lyase

Gene

Hccs

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Links covalently the heme group to the apoprotein of cytochrome c.UniRule annotation

Catalytic activityi

Holocytochrome c = apocytochrome c + heme.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionLyaseUniRule annotation
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c heme lyaseUniRule annotation (EC:4.4.1.17UniRule annotation)
Gene namesi
Name:HccsImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:106911. Hccs.

Subcellular locationi

  • Mitochondrion inner membrane UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiQ8BP79.
PeptideAtlasiQ8BP79.

Interactioni

Protein-protein interaction databases

IntActiQ8BP79. 1 interactor.
MINTiMINT-4111759.

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c-type heme lyase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3996. Eukaryota.
ENOG410YAUW. LUCA.
HOVERGENiHBG001566.

Family and domain databases

InterProiView protein in InterPro
IPR000511. Cyt_C/C1_haem_lyase.
PANTHERiPTHR12743. PTHR12743. 1 hit.
PfamiView protein in Pfam
PF01265. Cyto_heme_lyase. 1 hit.
PROSITEiView protein in PROSITE
PS00821. CYTO_HEME_LYASE_1. 1 hit.
PS00822. CYTO_HEME_LYASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8BP79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGASASSPAT AVNASNASDG QPASPPSGCP MHKGQRKGCP VTAATSDLTS
60 70 80 90 100
ESKAHTVPAH QDRAYDYVEC PVTGARAKDK ESLDPSNLMP PPNQTPSPDQ
110 120 130 140 150
PFTLSTSREE SSIPRADSEK KWVYPSEQMF WNAMLRKGWK WKDDDISQKD
160 170 180 190 200
MYNIIRIHNQ NNEQAWKEIL KWEALHAHEC PCGPSLVRFG GKAREYSPRA
210 220 230 240 250
RIRSWMGYEL PFDRHDWIIN RCGTEVRYVI DYYDGGEVNK EYQFTILDVR
260 270
TAFDSFSAVW DRMKVAWWRW TS
Length:272
Mass (Da):30,982
Last modified:March 1, 2003 - v1
Checksum:iAAAD63DBB3FF7387
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK077566 mRNA. Translation: BAC36866.1.
RefSeqiNP_032248.3. NM_008222.5.
UniGeneiMm.284033.

Genome annotation databases

GeneIDi15159.

Similar proteinsi

Entry informationi

Entry nameiQ8BP79_MOUSE
AccessioniPrimary (citable) accession number: Q8BP79
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 5, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)