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Protein

60S ribosomal protein L24

Gene

Rpl24

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • assembly of large subunit precursor of preribosome Source: GO_Central
  • cytoplasmic translation Source: MGI
  • exit from mitosis Source: MGI
  • mitotic cell cycle checkpoint Source: MGI
  • optic nerve development Source: MGI
  • retina development in camera-type eye Source: MGI
  • retinal ganglion cell axon guidance Source: MGI
  • ribosomal large subunit assembly Source: MGI
  • translation Source: MGI

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L24
Gene namesi
Name:Rpl24
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:1915443 Rpl24

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001368691 – 15760S ribosomal protein L24Add BLAST157

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki2Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei27N6-acetyllysine; alternateCombined sources1
Cross-linki27Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity
Cross-linki35Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei77N6-acetyllysineBy similarity1
Modified residuei83PhosphothreonineCombined sources1
Modified residuei86PhosphoserineCombined sources1
Modified residuei93N6-acetyllysineBy similarity1
Modified residuei131N6-succinyllysineCombined sources1
Cross-linki147Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei149PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ8BP67
MaxQBiQ8BP67
PeptideAtlasiQ8BP67
PRIDEiQ8BP67
TopDownProteomicsiQ8BP67

PTM databases

iPTMnetiQ8BP67
PhosphoSitePlusiQ8BP67
SwissPalmiQ8BP67

Expressioni

Gene expression databases

BgeeiENSMUSG00000098274
CleanExiMM_RPL24
GenevisibleiQ8BP67 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi212718, 2 interactors
IntActiQ8BP67, 5 interactors
MINTiQ8BP67

Structurei

3D structure databases

ProteinModelPortaliQ8BP67
SMRiQ8BP67
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

GeneTreeiENSGT00550000074809
HOVERGENiHBG001066
InParanoidiQ8BP67
KOiK02896
OMAiFHQRKNP
OrthoDBiEOG091G0ZDB
TreeFamiTF312933

Family and domain databases

CDDicd00472 Ribosomal_L24e_L24, 1 hit
Gene3Di2.30.170.20, 1 hit
InterProiView protein in InterPro
IPR038630 L24e/L24_sf
IPR000988 Ribosomal_L24e-rel
IPR023442 Ribosomal_L24e_CS
IPR011017 TRASH_dom
PANTHERiPTHR10792 PTHR10792, 1 hit
PfamiView protein in Pfam
PF01246 Ribosomal_L24e, 1 hit
SMARTiView protein in SMART
SM00746 TRASH, 1 hit
PROSITEiView protein in PROSITE
PS01073 RIBOSOMAL_L24E, 1 hit

Sequencei

Sequence statusi: Complete.

Q8BP67-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVELCSFSG YKIYPGHGRR YARTDGKVFQ FLNAKCESAF LSKRNPRQIN
60 70 80 90 100
WTVLYRRKHK KGQSEEIQKK RTRRAVKFQR AITGASLADI MAKRNQKPEV
110 120 130 140 150
RKAQREQAIR AAKEAKKAKQ ASKKTAMAAA KAPTKAAPKQ KIVKPVKVSA

PRVGGKR
Length:157
Mass (Da):17,779
Last modified:January 16, 2004 - v2
Checksum:i1D48EEB7C0652574
GO

Sequence cautioni

The sequence AAH02110 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti14Y → N in BAC36903 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018731 mRNA Translation: BAB31374.1
AK077617 mRNA Translation: BAC36903.1
BC002110 mRNA Translation: AAH02110.2 Different initiation.
BC053377 mRNA Translation: AAH53377.1
BC058114 mRNA Translation: AAH58114.1
BC092008 mRNA Translation: AAH92008.1
CCDSiCCDS28218.1
RefSeqiNP_077180.1, NM_024218.4
UniGeneiMm.29221
Mm.482104

Genome annotation databases

EnsembliENSMUST00000023269; ENSMUSP00000023269; ENSMUSG00000098274
GeneIDi68193
KEGGimmu:68193
UCSCiuc007zlv.2 mouse

Similar proteinsi

Entry informationi

Entry nameiRL24_MOUSE
AccessioniPrimary (citable) accession number: Q8BP67
Secondary accession number(s): P38663, Q58EA4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: January 16, 2004
Last modified: June 20, 2018
This is version 130 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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