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Protein
Submitted name:

Oxysterols receptor LXR-beta

Gene

Nr1h2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi72 – 149Nuclear receptorPROSITE-ProRule annotationAdd BLAST78

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Oxysterols receptor LXR-betaImported
Gene namesi
Name:Nr1h2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1352463 Nr1h2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

MaxQBiQ8BP65

Expressioni

Gene expression databases

BgeeiENSMUSG00000060601

Structurei

3D structure databases

SMRiQ8BP65
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini72 – 149Nuclear receptorInterPro annotationAdd BLAST78

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00870000136372
HOGENOMiHOG000220845
HOVERGENiHBG108655
TreeFamiTF352167

Family and domain databases

Gene3Di3.30.50.101 hit
InterProiView protein in InterPro
IPR023257 Liver_X_rcpt
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR02034 LIVERXRECPTR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8BP65-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSPTSSLDT PVPGNGSPQP STSATSPTIK EEGQETDPPP GSEGSSSAYI
60 70 80 90 100
VEPEDEPERK RKKGPAPKML GHELCRVCGD KASGFHYNVL SCEGCKGFFR
110 120 130 140 150
RSVVHGGAGR YACRGSGTCQ MDAFMRRKCQ LCRLRKCKEA GMREQCVLSE
160 170 180 190 200
EQIRKKRIQK QQQQQPPPPS EPAASSSGRP AASPGTSEAS SQGSGEGEGI
210 220 230 240 250
QLTAAQELMI QQLVAAQLQC NKRSFSDQPK VTPWPLGADP QSRDARQQRF
260 270 280 290 300
AHFTELAIIS VQEIVDFAKQ VPGFLQLGRE DQIALLKAST IEIMLLETAR
310 320 330 340 350
RYNHETECIT FLKDFTYSKD DFHRAGLQVE FINPIFEFSR AMRRLGLDDA
360 370 380 390 400
EYALLIAINI FSADRPNVQE PSRVEALQQP YVEALLSYTR IKRPQDQLRF
410 420 430 440
PRMLMKLVSL RTLSSVHSEQ VFALRLQDKK LPPLLSEIWD VHE
Length:443
Mass (Da):49,394
Last modified:March 1, 2003 - v1
Checksum:i362DCB2D21034F29
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC149607 Genomic DNA No translation available.
AC157653 Genomic DNA No translation available.
AK077620 mRNA Translation: BAC36906.1
AK156777 mRNA Translation: BAE33850.1
RefSeqiNP_001272447.1, NM_001285518.1
NP_001272448.1, NM_001285519.1
NP_033499.1, NM_009473.3
UniGeneiMm.968

Genome annotation databases

EnsembliENSMUST00000107910; ENSMUSP00000103543; ENSMUSG00000060601
ENSMUST00000107911; ENSMUSP00000103544; ENSMUSG00000060601
GeneIDi22260
UCSCiuc009gqb.2 mouse

Similar proteinsi

Entry informationi

Entry nameiQ8BP65_MOUSE
AccessioniPrimary (citable) accession number: Q8BP65
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: April 25, 2018
This is version 136 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported