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Protein

Kelch repeat and BTB domain-containing protein 11

Gene

Kbtbd11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Kelch repeat and BTB domain-containing protein 11
Gene namesi
Name:Kbtbd11
Synonyms:Kiaa0711
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:1922151. Kbtbd11.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001190911 – 633Kelch repeat and BTB domain-containing protein 11Add BLAST633

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei70PhosphoserineCombined sources1
Modified residuei73PhosphoserineCombined sources1
Modified residuei92PhosphoserineCombined sources1
Modified residuei95PhosphoserineCombined sources1
Modified residuei107PhosphoserineCombined sources1
Modified residuei113PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ8BNW9.
MaxQBiQ8BNW9.
PaxDbiQ8BNW9.
PeptideAtlasiQ8BNW9.
PRIDEiQ8BNW9.

PTM databases

iPTMnetiQ8BNW9.
PhosphoSitePlusiQ8BNW9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000055675.
CleanExiMM_KBTBD11.
GenevisibleiQ8BNW9. MM.

Interactioni

Protein-protein interaction databases

IntActiQ8BNW9. 1 interactor.
STRINGi10090.ENSMUSP00000068321.

Structurei

3D structure databases

ProteinModelPortaliQ8BNW9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini146 – 206BTBPROSITE-ProRule annotationAdd BLAST61
Repeati317 – 365Kelch 1Add BLAST49
Repeati366 – 418Kelch 2Add BLAST53
Repeati419 – 463Kelch 3Add BLAST45
Repeati465 – 506Kelch 4Add BLAST42

Sequence similaritiesi

Contains 1 BTB (POZ) domain.PROSITE-ProRule annotation
Contains 4 Kelch repeats.Curated

Keywords - Domaini

Kelch repeat, Repeat

Phylogenomic databases

eggNOGiKOG1072. Eukaryota.
ENOG4110X8D. LUCA.
GeneTreeiENSGT00760000118825.
HOGENOMiHOG000246990.
HOVERGENiHBG081849.
InParanoidiQ8BNW9.
KOiK10476.
OMAiVGGECLF.
OrthoDBiEOG091G02D9.
TreeFamiTF328485.

Family and domain databases

Gene3Di2.120.10.80. 1 hit.
InterProiIPR000210. BTB/POZ_dom.
IPR015915. Kelch-typ_b-propeller.
IPR006652. Kelch_1.
IPR011333. SKP1/BTB/POZ.
[Graphical view]
PfamiPF00651. BTB. 1 hit.
PF01344. Kelch_1. 1 hit.
[Graphical view]
SMARTiSM00225. BTB. 1 hit.
SM00612. Kelch. 3 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BNW9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENSVAPFVL YSGTEPRTPG EDSLPLPAEE EGAASTAQTP CSLSASLCFS
60 70 80 90 100
SGDDSPPQSR ASAAEGSEAS PPSLRSDLRV VETQWDVSSA ASPESPEECA
110 120 130 140 150
RPEEPASPED PPSRHEHARP VELESLDELG EPVPVPPGVG SVHGEPDLVI
160 170 180 190 200
EVAGRRLRAH KAVLAARSDY FRARASRDVL RVQGVSFTAL RLLLADAYSG
210 220 230 240 250
RMAGVRPDNV AEVVAGARRL QLPGAAQRAT EAMAPQLSLD NCYEVLSAGK
260 270 280 290 300
RQRLTELRDA AYRFMSDHYL EVLREPAVFG RLSGAERDLL LRRRLCTGRA
310 320 330 340 350
CLLAAALGTT GERSGSRPQS PSGDAESRGD AAVYCYQAEA GEWRELTRLP
360 370 380 390 400
EGAPARGCGL CVLFNYLFLA GGVAPAGPDG RARPSDQVYC YNPVTDSWST
410 420 430 440 450
VRPLRQARSQ VQLLALDGHL YAVGGECLLS VERYDPRADR WTAVAPLPRG
460 470 480 490 500
AFAVAHEAAT CNGEIYVSGG SLFYRLLKYD PRRDEWQECP CSSSRERSAD
510 520 530 540 550
MVALDGFLYR FDLCGSRGEA QAAVGSGGGV SVFRYHCLAK QWSQCAVHLR
560 570 580 590 600
PPGAPAGLQP FRCVALDGTI YCVSRAGTWR FVPSQDTEAG SDMGPGGSFE
610 620 630
PEPLGSPLDV RGVLFPFVLN LPEKPDRGEQ GAV
Length:633
Mass (Da):67,946
Last modified:July 27, 2011 - v3
Checksum:i2D37E3C68C98EC73
GO

Sequence cautioni

The sequence BAC98007 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti173A → S in BAC37803 (PubMed:16141072).Curated1
Sequence conflicti369L → V in BAC98007 (PubMed:14621295).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK129197 mRNA. Translation: BAC98007.1. Different initiation.
AK080001 mRNA. Translation: BAC37803.1.
BC080858 mRNA. Translation: AAH80858.1.
CCDSiCCDS52493.1.
RefSeqiNP_083392.1. NM_029116.2.
XP_006508978.1. XM_006508915.1.
XP_006508979.1. XM_006508916.2.
UniGeneiMm.46675.

Genome annotation databases

EnsembliENSMUST00000069399; ENSMUSP00000068321; ENSMUSG00000055675.
ENSMUST00000183471; ENSMUSP00000139292; ENSMUSG00000055675.
GeneIDi74901.
KEGGimmu:74901.
UCSCiuc009kzk.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK129197 mRNA. Translation: BAC98007.1. Different initiation.
AK080001 mRNA. Translation: BAC37803.1.
BC080858 mRNA. Translation: AAH80858.1.
CCDSiCCDS52493.1.
RefSeqiNP_083392.1. NM_029116.2.
XP_006508978.1. XM_006508915.1.
XP_006508979.1. XM_006508916.2.
UniGeneiMm.46675.

3D structure databases

ProteinModelPortaliQ8BNW9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8BNW9. 1 interactor.
STRINGi10090.ENSMUSP00000068321.

PTM databases

iPTMnetiQ8BNW9.
PhosphoSitePlusiQ8BNW9.

Proteomic databases

EPDiQ8BNW9.
MaxQBiQ8BNW9.
PaxDbiQ8BNW9.
PeptideAtlasiQ8BNW9.
PRIDEiQ8BNW9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000069399; ENSMUSP00000068321; ENSMUSG00000055675.
ENSMUST00000183471; ENSMUSP00000139292; ENSMUSG00000055675.
GeneIDi74901.
KEGGimmu:74901.
UCSCiuc009kzk.2. mouse.

Organism-specific databases

CTDi9920.
MGIiMGI:1922151. Kbtbd11.
RougeiSearch...

Phylogenomic databases

eggNOGiKOG1072. Eukaryota.
ENOG4110X8D. LUCA.
GeneTreeiENSGT00760000118825.
HOGENOMiHOG000246990.
HOVERGENiHBG081849.
InParanoidiQ8BNW9.
KOiK10476.
OMAiVGGECLF.
OrthoDBiEOG091G02D9.
TreeFamiTF328485.

Miscellaneous databases

ChiTaRSiKbtbd11. mouse.
PROiQ8BNW9.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000055675.
CleanExiMM_KBTBD11.
GenevisibleiQ8BNW9. MM.

Family and domain databases

Gene3Di2.120.10.80. 1 hit.
InterProiIPR000210. BTB/POZ_dom.
IPR015915. Kelch-typ_b-propeller.
IPR006652. Kelch_1.
IPR011333. SKP1/BTB/POZ.
[Graphical view]
PfamiPF00651. BTB. 1 hit.
PF01344. Kelch_1. 1 hit.
[Graphical view]
SMARTiSM00225. BTB. 1 hit.
SM00612. Kelch. 3 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiKBTBB_MOUSE
AccessioniPrimary (citable) accession number: Q8BNW9
Secondary accession number(s): A3KME3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: July 27, 2011
Last modified: November 2, 2016
This is version 110 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.