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Q8BNU7

- Q8BNU7_MOUSE

UniProt

Q8BNU7 - Q8BNU7_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Nedd4

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. proline-rich region binding Source: MGI
  2. sodium channel inhibitor activity Source: MGI
  3. ubiquitin-protein transferase activity Source: MGI

GO - Biological processi

  1. adaptive immune response Source: MGI
  2. blood vessel morphogenesis Source: MGI
  3. development involved in symbiotic interaction Source: Ensembl
  4. endocardial cushion development Source: MGI
  5. glucocorticoid receptor signaling pathway Source: Ensembl
  6. negative regulation of sodium ion transport Source: MGI
  7. negative regulation of transcription from RNA polymerase II promoter Source: MGI
  8. negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage Source: Ensembl
  9. neuromuscular junction development Source: MGI
  10. neuron projection development Source: Ensembl
  11. outflow tract morphogenesis Source: MGI
  12. positive regulation of nucleocytoplasmic transport Source: Ensembl
  13. positive regulation of phosphatidylinositol 3-kinase signaling Source: Ensembl
  14. positive regulation of protein catabolic process Source: MGI
  15. progesterone receptor signaling pathway Source: Ensembl
  16. protein monoubiquitination Source: MGI
  17. protein targeting to lysosome Source: Ensembl
  18. protein ubiquitination Source: MGI
  19. protein ubiquitination involved in ubiquitin-dependent protein catabolic process Source: MGI
  20. receptor catabolic process Source: Ensembl
  21. receptor internalization Source: Ensembl
  22. regulation of membrane potential Source: Ensembl
  23. regulation of potassium ion transmembrane transporter activity Source: Ensembl
  24. regulation of synapse organization Source: MGI
  25. T cell activation Source: MGI
  26. transmission of virus Source: Ensembl
  27. ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Nedd4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97297. Nedd4.

Subcellular locationi

GO - Cellular componenti

  1. cell cortex Source: Ensembl
  2. chromatin Source: Ensembl
  3. cytoplasm Source: MGI
  4. cytosol Source: MGI
  5. Golgi apparatus Source: Ensembl
  6. membrane Source: MGI
  7. nucleus Source: RefGenome
  8. perinuclear region of cytoplasm Source: Ensembl
  9. plasma membrane Source: Ensembl
  10. ubiquitin ligase complex Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ8BNU7.
ExpressionAtlasiQ8BNU7. baseline and differential.
GenevestigatoriQ8BNU7.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034740.

Structurei

3D structure databases

ProteinModelPortaliQ8BNU7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 C2 domain.UniRule annotation

Family and domain databases

Gene3Di2.60.40.150. 1 hit.
InterProiIPR000008. C2_dom.
[Graphical view]
PfamiPF00168. C2. 1 hit.
[Graphical view]
SUPFAMiSSF49562. SSF49562. 1 hit.
PROSITEiPS50004. C2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8BNU7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSSDMAADES EAPVLSEDEV WEFCLDKTED GGGSPGSDVT DTCEPPCGCW
60 70 80 90 100
ELNPNSLEEE HVLFTADPYL ELHNDDTRVV RVKVIAGIGL AKKDILGASD
110 120
PYVRVTLYDP MSGILTSVQT KTIKKSLNP
Length:129
Mass (Da):14,018
Last modified:October 11, 2005 - v2
Checksum:i22C31B6179365691
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei129 – 1291Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK080349 mRNA. Translation: BAC37885.2.
UniGeneiMm.279923.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK080349 mRNA. Translation: BAC37885.2 .
UniGenei Mm.279923.

3D structure databases

ProteinModelPortali Q8BNU7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000034740.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:97297. Nedd4.

Miscellaneous databases

ChiTaRSi NEDD4. mouse.
SOURCEi Search...

Gene expression databases

Bgeei Q8BNU7.
ExpressionAtlasi Q8BNU7. baseline and differential.
Genevestigatori Q8BNU7.

Family and domain databases

Gene3Di 2.60.40.150. 1 hit.
InterProi IPR000008. C2_dom.
[Graphical view ]
Pfami PF00168. C2. 1 hit.
[Graphical view ]
SUPFAMi SSF49562. SSF49562. 1 hit.
PROSITEi PS50004. C2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.

Entry informationi

Entry nameiQ8BNU7_MOUSE
AccessioniPrimary (citable) accession number: Q8BNU7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: October 11, 2005
Last modified: October 29, 2014
This is version 73 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)