Q8BNP7 (Q8BNP7_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein EMBL BAC38073.1

Gene names

Name:

Apc MGI 88039

Organism

Mus musculus (Mouse) EMBL BAC38073.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1056 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	T cell differentiation in thymus Inferred from mutant phenotype PubMed 16025118. Source: MGI anterior/posterior pattern specification Inferred from mutant phenotype PubMed 12645927. Source: MGI axis specification Inferred from mutant phenotype PubMed 12645927. Source: MGI axonogenesis Inferred from mutant phenotype PubMed 15207235PubMed 18716223. Source: MGI canonical Wnt receptor signaling pathway Inferred from mutant phenotype PubMed 16887818. Source: MGI cell cycle arrest Inferred from electronic annotation. Source: Compara cell migration Inferred from mutant phenotype PubMed 15198980. Source: MGI chromosome organization Inferred from mutant phenotype PubMed 17200209. Source: MGI cytokinesis after mitosis Inferred from mutant phenotype PubMed 17570218PubMed 17893240. Source: MGI cytoplasmic microtubule organization Inferred from genetic interaction PubMed 18716223. Source: MGI dorsal/ventral pattern formation Inferred from mutant phenotype PubMed 12645927. Source: MGI hair follicle development Inferred from mutant phenotype PubMed 17002498. Source: MGI kidney development Inferred from mutant phenotype PubMed 15550389. Source: MGI mitotic metaphase/anaphase transition Inferred from mutant phenotype PubMed 15767571PubMed 16025118. Source: MGI mitotic spindle assembly checkpoint Inferred from electronic annotation. Source: Compara muscle cell homeostasis Inferred from genetic interaction PubMed 18056981. Source: MGI negative regulation of MAPK cascade Inferred from mutant phenotype PubMed 16478791. Source: MGI negative regulation of apoptotic process Inferred from mutant phenotype PubMed 11756652PubMed 16950562. Source: MGI negative regulation of canonical Wnt receptor signaling pathway Inferred from mutant phenotype PubMed 11756652PubMed 15198980PubMed 15563600. Source: MGI negative regulation of cyclin-dependent protein serine/threonine kinase activity Inferred from electronic annotation. Source: Compara negative regulation of epithelial cell proliferation involved in prostate gland development Inferred from mutant phenotype PubMed 17363566. Source: MGI negative regulation of microtubule depolymerization Inferred from mutant phenotype PubMed 16525027. Source: MGI negative regulation of odontogenesis Inferred from mutant phenotype PubMed 17002498. Source: MGI positive regulation of apoptotic process Inferred from mutant phenotype PubMed 17227893. Source: MGI positive regulation of cell adhesion Inferred from mutant phenotype PubMed 16368433. Source: MGI positive regulation of cell division Inferred from mutant phenotype PubMed 16950562. Source: MGI positive regulation of cell migration Inferred from mutant phenotype PubMed 17192415. Source: MGI positive regulation of epithelial cell differentiation Inferred from genetic interaction PubMed 15314168. Source: MGI positive regulation of microtubule polymerization Inferred from mutant phenotype PubMed 16525027. Source: MGI positive regulation of protein catabolic process Inferred from mutant phenotype PubMed 16478791. Source: MGI positive regulation of pseudopodium assembly Inferred from electronic annotation. Source: Compara protein complex assembly Inferred from electronic annotation. Source: Compara proximal/distal pattern formation Inferred from mutant phenotype PubMed 16887818. Source: MGI regulation of attachment of spindle microtubules to kinetochore Inferred from mutant phenotype PubMed 17227893. Source: MGI regulation of cell cycle Inferred from mutant phenotype PubMed 8988060. Source: MGI regulation of nitrogen compound metabolic process Inferred from mutant phenotype PubMed 16740478. Source: MGI regulation of osteoblast differentiation Inferred from mutant phenotype PubMed 15802266. Source: MGI regulation of osteoclast differentiation Inferred from mutant phenotype PubMed 15802266. Source: MGI response to DNA damage stimulus Inferred from electronic annotation. Source: Compara retina development in camera-type eye Inferred from mutant phenotype PubMed 10982921. Source: MGI skin development Inferred from mutant phenotype PubMed 9453487. Source: MGI somatic stem cell maintenance Inferred from mutant phenotype PubMed 1541640. Source: MGI thymus development Inferred from mutant phenotype PubMed 16025118PubMed 17002498. Source: MGI
Cellular_component	axonal growth cone Inferred from direct assay PubMed 18716223. Source: MGI beta-catenin destruction complex Inferred from electronic annotation. Source: Compara cell projection membrane Inferred from direct assay PubMed 16621792. Source: MGI cell-cell adherens junction Inferred from electronic annotation. Source: Compara centrosome Inferred from electronic annotation. Source: Compara cytoplasmic microtubule Inferred from direct assay PubMed 16525027PubMed 16621792. Source: MGI kinetochore Inferred from electronic annotation. Source: Compara lamellipodium Inferred from electronic annotation. Source: Compara lateral plasma membrane Inferred from electronic annotation. Source: Compara microtubule plus end Inferred from direct assay PubMed 18716223. Source: MGI nucleus Inferred from direct assay PubMed 10346819. Source: MGI ruffle membrane Inferred from electronic annotation. Source: Compara tight junction Inferred from electronic annotation. Source: Compara
Molecular_function	beta-catenin binding Inferred from direct assay PubMed 10346819. Source: MGI microtubule plus-end binding Inferred from direct assay PubMed 18716223. Source: MGI protein kinase regulator activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1056	1	EMBL BAC38073.1

Sequences

	Sequence		Length	Mass (Da)
	Q8BNP7 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 86C79FDC12C23FAB	FASTA	1,056	117,633
	10 20 30 40 50 60 MAAASYDQLL KQVEALKMEN SNLRQELEDN SNHLTKLETE ASNMKEVLKQ LQGSIEDETM 70 80 90 100 110 120 TSGQIDLLER LKEFNLDSNF PGVKLRSKMS LRSYGSREGS VSSRSGECSP VPMGSFPRRT 130 140 150 160 170 180 FVNGSRESTG YLEELEKERS LLLADLDKEE KEKDWYYAQL QNLTKRIDSL PLTENFSLQT 190 200 210 220 230 240 DMTRRQLEYE ARQIRAAMEE QLGTCQDMEK RAQRRIARIQ QIEKDILRVR QLLQSQAAEA 250 260 270 280 290 300 ERSSQSRHDA ASHEAGRQHE GHGVAESNTA ASSSGQSPAT RVDHETASVL SSSGTHSAPR 310 320 330 340 350 360 RLTSHLGTKV EMVYSLLSML GTHDKDDMSR TLLAMSSSQD SCISMRQSGC LPLLIQLLHG 370 380 390 400 410 420 NDKDSVLLGN SRGSKEARAR ASAALHNIIH SQPDDKRGRR EIRVLHLLEQ IRAYCETCWE 430 440 450 460 470 480 WQEAHEQGMD QDKNPMPAPV EHQICPAVCV LMKLSFDEEH RHAMNELGGL QAIAELLQVD 490 500 510 520 530 540 CEMYGLTNDH YSVTLRRYAG MALTNLTFGD VANKATLCSM KGCMRALVAQ LKSESEDLQQ 550 560 570 580 590 600 VIASVLRNLS WRADVNSKKT LREVGSVKAL MECALEVKKE STLKSVLSAL WNLSAHCTEN 610 620 630 640 650 660 KADICAVDGA LAFLVGTLTY RSQTNTLAII ESGGGILRNV SSLIATNEDH RQILRENNCL 670 680 690 700 710 720 QTLLQHLKSH SLTIVSNACG TLWNLSARNP KDQEALWDMG AVSMLKNLIH SKHKMIAMGS 730 740 750 760 770 780 AAALRNLMAN RPAKYKDANI MSPGSSLPSL HVRKQKALEA ELDAQHLSET FDNIDNLSPK 790 800 810 820 830 840 ASHRSKQRHK QNLYGDYAFD ANRHDDSRSD NFNTGNMTVL SPYLNTTVLP SSSSSRGSLD 850 860 870 880 890 900 SSRSEKDRSL ERERGIGLSA YHPTTENAGT SSKRGLQITT TAAQIAKVME EVSAIHTSQD 910 920 930 940 950 960 DRSSASTTEF HCVADDRSAA RRSSASHTHS NTYNFTKSEN SNRTCSMPYA KVEYKRSSND 970 980 990 1000 1010 1020 SLNSVTSSDG YGKRGQMKPS VESYSEDDES KFCSYGQYPA DLAHKIHSAN HMDDNDGELD 1030 1040 1050 TPINYSLKYS DEQLNSGRQS PSQNERWARP KHVIED

References

[1]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC38073.1. Tissue: Adipose EMBL BAC38073.1.
[2]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC38073.1. Tissue: Adipose EMBL BAC38073.1.
[3]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC38073.1. Tissue: Adipose EMBL BAC38073.1.
[4]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC38073.1. Tissue: Adipose EMBL BAC38073.1.
[5]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC38073.1. Tissue: Adipose EMBL BAC38073.1.
[6]	Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P., Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W., Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T., Hori F., Imotani K. , Ishii Y., Itoh M., Kagawa I., Kasukawa T., Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M., Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y., Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H., Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M., Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T., Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y. Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC38073.1. Tissue: Adipose EMBL BAC38073.1.
[7]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC38073.1. Tissue: Adipose EMBL BAC38073.1.
[8]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC38073.1. Tissue: Adipose EMBL BAC38073.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK080907 mRNA. Translation: BAC38073.1.
IPI	IPI00896736.
RefSeq	NP_031488.2. NM_007462.3.
UniGene	Mm.384171.
3D structure databases
HSSP	HSSP built from PDB template 1DEB based on UniProtKB P25054.
ProteinModelPortal	Q8BNP7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8BNP7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	11789.
KEGG	mmu:11789.
Organism-specific databases
CTD	324.
MGI	MGI:88039. Apc.
Phylogenomic databases
InParanoid	Q8BNP7.
KO	K02085.
Gene expression databases
ArrayExpress	Q8BNP7.
Bgee	Q8BNP7.
Genevestigator	Q8BNP7.
Family and domain databases
Gene3D	1.25.10.10. 2 hits.
InterPro	IPR026836. APC. IPR009240. APC_15aa_rpt. IPR026831. APC_dom. IPR026818. Apc_fam. IPR011989. ARM-like. IPR016024. ARM-type_fold. IPR000225. Armadillo. [Graphical view]
PANTHER	PTHR12607. PTHR12607. 1 hit. PTHR12607:SF2. PTHR12607:SF2. 1 hit.
Pfam	PF05972. APC_15aa. 1 hit. PF00514. Arm. 3 hits. PF11414. Suppressor_APC. 1 hit. [Graphical view]
SMART	SM00185. ARM. 6 hits. [Graphical view]
SUPFAM	SSF48371. ARM-type_fold. 1 hit.
PROSITE	PS50176. ARM_REPEAT. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	APC. mouse.
NextBio	279609.
SOURCE	Search...

Entry information

Entry name

Q8BNP7_MOUSE

Accession

Primary (citable) accession number: Q8BNP7

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	May 1, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)