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Q8BNF8

- Q8BNF8_MOUSE

UniProt

Q8BNF8 - Q8BNF8_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Vcp

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 96 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ADP binding Source: Ensembl
    2. ATPase activity Source: Ensembl
    3. ATP binding Source: UniProtKB-KW
    4. protein binding Source: MGI

    GO - Biological processi

    1. activation of cysteine-type endopeptidase activity involved in apoptotic process Source: MGI
    2. aggresome assembly Source: MGI
    3. double-strand break repair Source: Ensembl
    4. ER to Golgi vesicle-mediated transport Source: Ensembl
    5. positive regulation of proteasomal ubiquitin-dependent protein catabolic process Source: Ensembl
    6. positive regulation of protein complex assembly Source: Ensembl
    7. protein homooligomerization Source: Ensembl
    8. protein N-linked glycosylation via asparagine Source: Ensembl
    9. retrograde protein transport, ER to cytosol Source: Ensembl
    10. translesion synthesis Source: Ensembl
    11. ubiquitin-dependent protein catabolic process Source: MGI

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:VcpImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:99919. Vcp.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: MGI
    2. endoplasmic reticulum Source: Ensembl
    3. lipid particle Source: Ensembl
    4. nucleus Source: Ensembl
    5. proteasome complex Source: Ensembl
    6. protein complex Source: MGI
    7. site of double-strand break Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiQ8BNF8.

    Expressioni

    Gene expression databases

    BgeeiQ8BNF8.
    GenevestigatoriQ8BNF8.

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-1736094.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8BNF8.
    SMRiQ8BNF8. Positions 1-680.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AAA ATPase family.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG001226.
    InParanoidiQ8BNF8.

    Family and domain databases

    Gene3Di3.10.330.10. 1 hit.
    3.40.50.300. 2 hits.
    InterProiIPR003593. AAA+_ATPase.
    IPR005938. AAA_ATPase_CDC48.
    IPR003959. ATPase_AAA_core.
    IPR003960. ATPase_AAA_CS.
    IPR004201. Cdc48_dom2.
    IPR029067. CDC48_domain_2-like.
    IPR027417. P-loop_NTPase.
    IPR015415. Vps4_C.
    [Graphical view]
    PfamiPF00004. AAA. 2 hits.
    PF02933. CDC48_2. 1 hit.
    PF09336. Vps4_C. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 2 hits.
    SM01072. CDC48_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 2 hits.
    SSF54585. SSF54585. 1 hit.
    TIGRFAMsiTIGR01243. CDC48. 1 hit.
    PROSITEiPS00674. AAA. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8BNF8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNRVVRNNLR VRLGDVISIQ PCPDVKYGKR IHVLPIDDTV EGITGNLFEV    50
    YLKPYFLEAY RPIRKGDIFL VRGGMRAVEF KVVETDPSPY CIVAPDTVIH 100
    CEGEPIKRED EEESLNEVGY DDIGGCRKQL AQIKEMVELP LRHPALFKAI 150
    GVKPPRGILL YGPPGTGKTL IARAVANETG AFFFLINGPE IMSKLAGESE 200
    SNLRKAFEEA EKNAPAIIFI DELDAIAPKR EKTHGEVERR IVSQLLTLMD 250
    GLKQRAHVIV MAATNRPNSI DPALRRFGRF DREVDIGIPD ATGRLEILQI 300
    HTKNMKLADD VDLEQVANET HGHVGADLAA LCSEAALQAI RKKMDLIDLE 350
    DETIDAEVMN SLAVTMDDFR WALSQSNPSA LRETVVEVPQ VTWEDIGGLE 400
    DVKRELQELV QYPVEHPDKF LKFGMTPSKG VLFYGPPGCG KTLLAKAIAN 450
    ECQANFISIK GPELLTMWFG ESEANVREIF DKARQAAPCV LFFDELDSIA 500
    KARGGNIGDG GGAADRVINQ ILTEMDGMST KKNVFIIGAT NRPDIIDPAI 550
    LRPGRLDQLI YIPLPDEKSR VAILKANLRK SPVAKDVDLE FLAKMTNGFS 600
    GADLTEICQR ACKLAIRESI ESEIRRERER QTNPSAMEVE EDDPVPEIRR 650
    DHFEEAMRFA RRSVSDNDIR KYEMFAQTLQ QSRGFGSFRF PSGNQGGAGP 700
    SQGSGGGTGG SVYTEDNDDD LYG 723
    Length:723
    Mass (Da):80,149
    Last modified:March 1, 2003 - v1
    Checksum:iBE6571A7772AA778
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK083821 mRNA. Translation: BAC39028.1.
    UniGeneiMm.245976.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK083821 mRNA. Translation: BAC39028.1 .
    UniGenei Mm.245976.

    3D structure databases

    ProteinModelPortali Q8BNF8.
    SMRi Q8BNF8. Positions 1-680.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-1736094.

    Proteomic databases

    PRIDEi Q8BNF8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:99919. Vcp.

    Phylogenomic databases

    HOVERGENi HBG001226.
    InParanoidi Q8BNF8.

    Miscellaneous databases

    ChiTaRSi VCP. mouse.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q8BNF8.
    Genevestigatori Q8BNF8.

    Family and domain databases

    Gene3Di 3.10.330.10. 1 hit.
    3.40.50.300. 2 hits.
    InterProi IPR003593. AAA+_ATPase.
    IPR005938. AAA_ATPase_CDC48.
    IPR003959. ATPase_AAA_core.
    IPR003960. ATPase_AAA_CS.
    IPR004201. Cdc48_dom2.
    IPR029067. CDC48_domain_2-like.
    IPR027417. P-loop_NTPase.
    IPR015415. Vps4_C.
    [Graphical view ]
    Pfami PF00004. AAA. 2 hits.
    PF02933. CDC48_2. 1 hit.
    PF09336. Vps4_C. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 2 hits.
    SM01072. CDC48_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 2 hits.
    SSF54585. SSF54585. 1 hit.
    TIGRFAMsi TIGR01243. CDC48. 1 hit.
    PROSITEi PS00674. AAA. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Spinal ganglionImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Spinal ganglionImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Spinal ganglionImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Spinal ganglionImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Spinal ganglionImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Spinal ganglionImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Spinal ganglionImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Spinal ganglionImported.

    Entry informationi

    Entry nameiQ8BNF8_MOUSE
    AccessioniPrimary (citable) accession number: Q8BNF8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 96 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)