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Protein
Submitted name:

Putative uncharacterized protein

Gene

Tpp1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Cofactori

Ca2+PROSITE-ProRule annotationNote: Binds 1 Ca2+ ion per subunit.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei29Charge relay systemPROSITE-ProRule annotation1
Active sitei33Charge relay systemPROSITE-ProRule annotation1
Active sitei232Charge relay systemPROSITE-ProRule annotation1
Metal bindingi274CalciumPROSITE-ProRule annotation1
Metal bindingi275Calcium; via carbonyl oxygenPROSITE-ProRule annotation1
Metal bindingi298Calcium; via carbonyl oxygenPROSITE-ProRule annotation1
Metal bindingi300CalciumPROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine proteasePROSITE-ProRule annotation
LigandCalciumPROSITE-ProRule annotation, Metal-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Submitted name:
Tripeptidyl peptidase I, isoform CRA_aImported
Gene namesi
Name:Tpp1Imported
ORF Names:mCG_19720Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

PTM / Processingi

Proteomic databases

PeptideAtlasiQ8BNF3.

Expressioni

Gene expression databases

BgeeiENSMUSG00000030894.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000033184.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 320Peptidase S53InterPro annotationAdd BLAST320

Phylogenomic databases

eggNOGiENOG410IICY. Eukaryota.
COG4934. LUCA.
HOVERGENiHBG004449.

Family and domain databases

CDDicd04056. Peptidases_S53. 1 hit.
Gene3Di3.40.50.200. 1 hit.
InterProiView protein in InterPro
IPR000209. Peptidase_S8/S53_dom.
IPR030400. Sedolisin_dom.
SUPFAMiSSF52743. SSF52743. 1 hit.
PROSITEiView protein in PROSITE
PS51695. SEDOLISIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8BNF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLFGGSFTH QASVAKVVGK QGRGRAGIEA SLDVEYLMSA GANISTWVYS
60 70 80 90 100
SPGRHEAQEP FLQWLLLLSN ESSLPHVHTV SYGDDEDSLS SIYIQRVNTE
110 120 130 140 150
FMKAAARGLT LLFASGDTGA GCWSVSGRHK FRPSFPASSP YVTTVGGTSF
160 170 180 190 200
KNPFLITDEV VDYISGGGFS NVFPRPPYQE EAVAQFLKSS SHLPPSSYFN
210 220 230 240 250
ASGRAYPDVA ALSDGYWVVS NMVPIPWVSG TSASTPVFGG ILSLINEHRI
260 270 280 290 300
LNGRPPLGFL NPRLYQQHGT GLFDVTHGCH ESCLNEEVEG QGFCSGPGWD
310 320
PVTGWGTPNF PALLKTLLNP
Length:320
Mass (Da):34,523
Last modified:March 1, 2003 - v1
Checksum:i91DC3FBF778631C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK083832 mRNA. Translation: BAC39034.1.
CH466531 Genomic DNA. Translation: EDL16817.1.
CH466531 Genomic DNA. Translation: EDL16818.1.
UniGeneiMm.20837.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK083832 mRNA. Translation: BAC39034.1.
CH466531 Genomic DNA. Translation: EDL16817.1.
CH466531 Genomic DNA. Translation: EDL16818.1.
UniGeneiMm.20837.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000033184.

Proteomic databases

PeptideAtlasiQ8BNF3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IICY. Eukaryota.
COG4934. LUCA.
HOVERGENiHBG004449.

Miscellaneous databases

ChiTaRSiTpp1. mouse.

Gene expression databases

BgeeiENSMUSG00000030894.

Family and domain databases

CDDicd04056. Peptidases_S53. 1 hit.
Gene3Di3.40.50.200. 1 hit.
InterProiView protein in InterPro
IPR000209. Peptidase_S8/S53_dom.
IPR030400. Sedolisin_dom.
SUPFAMiSSF52743. SSF52743. 1 hit.
PROSITEiView protein in PROSITE
PS51695. SEDOLISIN. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ8BNF3_MOUSE
AccessioniPrimary (citable) accession number: Q8BNF3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: March 15, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.