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Protein

Integrator complex subunit 6-like

Gene

Ints6l

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Integrator complex subunit 6-like
Alternative name(s):
Protein DDX26B
Gene namesi
Name:Ints6l
Synonyms:Ddx26b
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:2442593. Ddx26b.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 861861Integrator complex subunit 6-likePRO_0000076216Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei617 – 6171PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ8BND4.
MaxQBiQ8BND4.
PaxDbiQ8BND4.
PeptideAtlasiQ8BND4.
PRIDEiQ8BND4.

PTM databases

iPTMnetiQ8BND4.
PhosphoSiteiQ8BND4.

Expressioni

Gene expression databases

BgeeiENSMUSG00000035967.
CleanExiMM_DDX26B.
ExpressionAtlasiQ8BND4. baseline and differential.
GenevisibleiQ8BND4. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000035379.

Structurei

3D structure databases

ProteinModelPortaliQ8BND4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini3 – 227225VWFAPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 VWFA domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3768. Eukaryota.
ENOG410XRER. LUCA.
GeneTreeiENSGT00390000016655.
HOGENOMiHOG000015308.
HOVERGENiHBG081468.
InParanoidiQ8BND4.
KOiK13180.
OMAiIGRSYCV.
OrthoDBiEOG091G03YA.
PhylomeDBiQ8BND4.
TreeFamiTF323386.

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR029307. INT_SG_DDX_CT_C.
IPR002035. VWF_A.
[Graphical view]
PfamiPF15300. INT_SG_DDX_CT_C. 1 hit.
PF13519. VWA_2. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 2 hits.
PROSITEiPS50234. VWFA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BND4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPILLFLIDT SASMNQRTDL GTSYLDIAKG AVELFLKLRA RDPASRGDRY
60 70 80 90 100
MLVTYDEPPY CIKAGWKENH ATFMNELKNL QASGLTTLGQ ALRSSFDLLN
110 120 130 140 150
LNRLISGIDN YGQGRNPFFL EPSILITITD GNKLTSTASV QEELHLPLNS
160 170 180 190 200
PLPGSELTKE PFRWDQRLFA LVLRLPGVAS TEPEQLGSVP SDESAITQMC
210 220 230 240 250
EVTGGRSYCV RTQRMLNQCL ESLVQKVQSG VVINFEKTGP DPLPVGEDTL
260 270 280 290 300
MELCRPSNLF AAQPWHSCHK LIYVRPNSKT GVPVGHWPIP ESFWPEQNLP
310 320 330 340 350
SLPPRTSHPV VRFSCVDCEP MVIDKLPFDK YELEPSPLTQ YILERKSPHT
360 370 380 390 400
CWQVFVTSSS KYNELGYPFG YLKASTTLTC VNLFVMPYNY PVLLPLLDDL
410 420 430 440 450
FKVHKLKPNL KWRQAFDSYL KTLPPYYLIT KLESDQILAS VGKKPPQEIG
460 470 480 490 500
IKVKNHSACG LPLAHNKSFR KLLKEIIGES APRLTELNPK EFAGFQVGLL
510 520 530 540 550
NKDLKPQTYR NAYDIPRRGL LDQLTRMRSN LLQTRKFIVG QDEDSLHSVP
560 570 580 590 600
VAQMGNYQEY LKMLASPLRE LDPDQPKRLH TFGNPFKQDK KGMMIDEADE
610 620 630 640 650
FVVGPQNKVK RPGEPNSPMS SKRRRSMSLL LRRAQTAPTV TNHVGGKGPL
660 670 680 690 700
SASWFPSCPS LVKHTFGHPD TTVIHDTHEE KMENGQSPPD GFLLKSAPAE
710 720 730 740 750
FMNVSGESFI SSQLDSLSDD FTGLRKDGFI HKPGNNILLG GAKTCSLSVA
760 770 780 790 800
DQKITMASAL ETVPNSMQIT PAMAQGINAD IKHQLMKEVR KFGRKYERIF
810 820 830 840 850
ILLEEVQGPL ETKKQFVEFT IKEAARFKRR VLIQYLEKVL EKIDSHHLLN
860
NVNHINSRSS C
Length:861
Mass (Da):96,941
Last modified:March 1, 2003 - v1
Checksum:i22D5D4A229FE08CD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK083942 mRNA. Translation: BAC39076.1.
BC066792 mRNA. Translation: AAH66792.1.
CCDSiCCDS30145.1.
RefSeqiNP_766367.1. NM_172779.4.
UniGeneiMm.474772.

Genome annotation databases

EnsembliENSMUST00000039374; ENSMUSP00000035379; ENSMUSG00000035967.
ENSMUST00000132428; ENSMUSP00000138630; ENSMUSG00000035967.
ENSMUST00000186445; ENSMUSP00000139507; ENSMUSG00000035967.
GeneIDi236790.
KEGGimmu:236790.
UCSCiuc009tgg.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK083942 mRNA. Translation: BAC39076.1.
BC066792 mRNA. Translation: AAH66792.1.
CCDSiCCDS30145.1.
RefSeqiNP_766367.1. NM_172779.4.
UniGeneiMm.474772.

3D structure databases

ProteinModelPortaliQ8BND4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000035379.

PTM databases

iPTMnetiQ8BND4.
PhosphoSiteiQ8BND4.

Proteomic databases

EPDiQ8BND4.
MaxQBiQ8BND4.
PaxDbiQ8BND4.
PeptideAtlasiQ8BND4.
PRIDEiQ8BND4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000039374; ENSMUSP00000035379; ENSMUSG00000035967.
ENSMUST00000132428; ENSMUSP00000138630; ENSMUSG00000035967.
ENSMUST00000186445; ENSMUSP00000139507; ENSMUSG00000035967.
GeneIDi236790.
KEGGimmu:236790.
UCSCiuc009tgg.2. mouse.

Organism-specific databases

CTDi236790.
MGIiMGI:2442593. Ddx26b.

Phylogenomic databases

eggNOGiKOG3768. Eukaryota.
ENOG410XRER. LUCA.
GeneTreeiENSGT00390000016655.
HOGENOMiHOG000015308.
HOVERGENiHBG081468.
InParanoidiQ8BND4.
KOiK13180.
OMAiIGRSYCV.
OrthoDBiEOG091G03YA.
PhylomeDBiQ8BND4.
TreeFamiTF323386.

Miscellaneous databases

PROiQ8BND4.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000035967.
CleanExiMM_DDX26B.
ExpressionAtlasiQ8BND4. baseline and differential.
GenevisibleiQ8BND4. MM.

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR029307. INT_SG_DDX_CT_C.
IPR002035. VWF_A.
[Graphical view]
PfamiPF15300. INT_SG_DDX_CT_C. 1 hit.
PF13519. VWA_2. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 2 hits.
PROSITEiPS50234. VWFA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiINT6L_MOUSE
AccessioniPrimary (citable) accession number: Q8BND4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: March 1, 2003
Last modified: September 7, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.