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Protein

Serine/threonine-protein phosphatase

Gene

Ppp2cb

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphataseUniRule annotation (EC:3.1.3.16UniRule annotation)
Gene namesi
Name:Ppp2cbImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1321161. Ppp2cb.

PTM / Processingi

Proteomic databases

PaxDbiQ8BN07.
PeptideAtlasiQ8BN07.
PRIDEiQ8BN07.

Expressioni

Gene expression databases

GenevisibleiQ8BN07. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000009774.

Structurei

3D structure databases

ProteinModelPortaliQ8BN07.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini90 – 956SER_THR_PHOSPHATASEInterPro annotation

Sequence similaritiesi

Belongs to the PPP phosphatase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0371. Eukaryota.
COG0639. LUCA.
HOVERGENiHBG000216.
KOiK04382.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8BN07-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ENQVRTLCEK AKEILTKESN VQEVRCPVTV CGDVHGQFHD LMELFRIGGK
60 70 80 90 100
SPDTNYLFMG DYVDRGYYSV ETVTLLVALK VRYPERITIL RGNHESRQIT
110 120 130 140 150
QVYGFYDECL RKYGNANVWK YFTDLFDYLP LTALVDGQIF CLNGGLSPSI
160 170 180 190 200
DTLDHIRALD RLQEVPHEGP MCDLLWSDPD DRGGWGISPR GAGYTFGQDI
210 220 230 240 250
SETFNHANGL TLVSRAHQLV MEGYNWCHDR NVVTIFSAPN YCYRCGNQAA
260 270 280
IMELDDTLKY SFLQFDPAPR RGEPHVTRRT PDYFL
Length:285
Mass (Da):32,644
Last modified:March 1, 2003 - v1
Checksum:iF6554898D5967259
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK090311 mRNA. Translation: BAC41164.1.
RefSeqiNP_059070.1. NM_017374.3.
UniGeneiMm.288765.
Mm.29301.

Genome annotation databases

GeneIDi19053.
KEGGimmu:19053.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK090311 mRNA. Translation: BAC41164.1.
RefSeqiNP_059070.1. NM_017374.3.
UniGeneiMm.288765.
Mm.29301.

3D structure databases

ProteinModelPortaliQ8BN07.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000009774.

Proteomic databases

PaxDbiQ8BN07.
PeptideAtlasiQ8BN07.
PRIDEiQ8BN07.

Protocols and materials databases

DNASUi19053.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi19053.
KEGGimmu:19053.

Organism-specific databases

CTDi5516.
MGIiMGI:1321161. Ppp2cb.

Phylogenomic databases

eggNOGiKOG0371. Eukaryota.
COG0639. LUCA.
HOVERGENiHBG000216.
KOiK04382.

Miscellaneous databases

ChiTaRSiPpp2cb. mouse.
SOURCEiSearch...

Gene expression databases

GenevisibleiQ8BN07. MM.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8BN07_MOUSE
AccessioniPrimary (citable) accession number: Q8BN07
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 6, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.