Q8BML9 (Q8BML9_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glutaminyl-tRNA synthetase EMBL AAH79854.1

Submitted name:
Uncharacterized protein Ensembl ENSMUSP00000006838

Gene names

Name:

Qars Ensembl ENSMUSP00000006838 MGI 1915851

Organism

Mus musculus (Mouse) EMBL BAC27018.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	775 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. RuleBase RU003489

Ontologies

Keywords
Biological process	Protein biosynthesis RuleBase RU003489
Ligand	ATP-binding RuleBase RU003489 Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase RuleBase RU003489 EMBL AAH79854.1 Ligase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glutaminyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glutamine-tRNA ligase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8BML9 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 54276290F5ED7A27	FASTA	775	87,677
	10 20 30 40 50 60 MATPDSLALF TGLGLSENKA RETLKNEALS TQLREAATQA HQILGSTIDK ATGVLLYDLV 70 80 90 100 110 120 SRLRDTRRRS FLVSYIANKK IHTGLQLSAA LEYVRSHPQD PIDTKDFEQE CGVGVVVTPE 130 140 150 160 170 180 QIEEAVESTI NKHQLQLLAE RYRFNMGLLM GEARAALRWA DGKMIKNEVD MQVLHLLGPK 190 200 210 220 230 240 MEADLVKKPK VAKARLEETD RKTAKDVVEK GEVAGQTLSL MEQLRGEALK FHKPGENYKT 250 260 270 280 290 300 PGYVITPYTM DLLKQHLEIT GGQVRTRFPP EPNGILHIGH AKAINFNFGY AKANNGICFL 310 320 330 340 350 360 RFDDTNPEKE EAKFFTAIYD MVTWLGYTPY KVTYASDYFD QLYAWAVELI HGGLAYVCHQ 370 380 390 400 410 420 RVEELKGHNP LPSPWRDRPK EESLLLFEAM RKGKFAEGEA TLRMKLVMED GKMDPVAYRV 430 440 450 460 470 480 KYTPHHRTGD KWCIYPTYDY THCLCDSIEH ITHSLCTKEF QARRSSYFWL CNALKVYCPV 490 500 510 520 530 540 QWEYGRLNLH YAVVSKRKIL QLVAAGAVRD WDDPRLFTLT ALRRRGFPPE AINNFCARVG 550 560 570 580 590 600 VTVAQTTMEP HLLEACVRDV LNDAAPRAMA VLEPLQVVIT NFPAPKPLDI RVPNFPADET 610 620 630 640 650 660 KGFHQVPFAS TVFIERSDFK EESEPGYKRL ASGQPVGLRH TGYVIELQNI VRGSSGCVER 670 680 690 700 710 720 LEVTCRRADA GEKPKAFIHW VSQPLVCEIR LYECLFQHKN PEDPVEVPGG FLSDLNPASL 730 740 750 760 770 QVVEGALVDC SVALAKPFDK FQFERLGYFS VDPDSHQGQI VFNRTVTLKE DPGKI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed: 16141073] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC27018.1. Tissue: Pituitary gland EMBL BAC27018.1.
[2]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed: 11076861] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC27018.1. Tissue: Pituitary gland EMBL BAC27018.1.
[3]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Mouse Genome Sequencing Consortium Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed: 19468303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6 Ensembl ENSMUSP00000006838.
[4]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC27018.1. Tissue: Pituitary gland EMBL BAC27018.1.
[5]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed: 10349636] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC27018.1. Tissue: Pituitary gland EMBL BAC27018.1.
[6]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed: 11042159] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC27018.1. Tissue: Pituitary gland EMBL BAC27018.1.
[7]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC27018.1. Tissue: Pituitary gland EMBL BAC27018.1.
[8]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC27018.1. Tissue: Pituitary gland EMBL BAC27018.1.
[9]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6 EMBL AAH79854.1. Tissue: Brain EMBL AAH79854.1.
[10]	Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y. Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE26552.1.
[11]	Ensembl Submitted (JUN-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000006838.
[12]	Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P., Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W., Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T., Hori F., Imotani K. , Ishii Y., Itoh M., Kagawa I., Kasukawa T., Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M., Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y., Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H., Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M., Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T., Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y. Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC27018.1. Tissue: Pituitary gland EMBL BAC27018.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT010508 Genomic DNA. No translation available. BC079854 mRNA. Translation: AAH79854.1. AK030554 mRNA. Translation: BAC27018.1. AK145632 mRNA. Translation: BAE26552.1. AK155759 mRNA. Translation: BAE33422.1.
IPI	IPI00223055.
RefSeq	NP_598555.2. NM_133794.2.
UniGene	Mm.272427.
3D structure databases
HSSP	HSSP built from PDB template 1NYL based on UniProtKB P00962.
ProteinModelPortal	Q8BML9.
SMR	Q8BML9. Positions 249-771.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8BML9.
Proteomic databases
PRIDE	Q8BML9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000006838; ENSMUSP00000006838; ENSMUSG00000032604.
GeneID	97541.
KEGG	mmu:97541.
NMPDR	fig|10090.3.peg.20866.
UCSC	uc009rpy.2. mouse.
Organism-specific databases
CTD	5859.
MGI	MGI:1915851. Qars.
Phylogenomic databases
HOVERGEN	HBG000889.
InParanoid	Q8BML9.
OMA	RMPTIAG.
PhylomeDB	Q8BML9.
Gene expression databases
ArrayExpress	Q8BML9.
Bgee	Q8BML9.
Genevestigator	Q8BML9.
Family and domain databases
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR004514. Gln-tRNA-synth_Ib. IPR007638. Gln-tRNA-synth_Ib_RNA-bd_2. IPR007639. Gln-tRNA-synth_Ib_RNA-bd_N. IPR000924. Glu/Gln-tRNA-synth_Ib. IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl. IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom. IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd. IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl. IPR011035. Ribosomal_L25/Gln-tRNA_synth. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:1.10.1160.10. Glu/Gln-tRNA-synth_Ic_a-bdl. 1 hit. G3DSA:2.40.240.10. Rbsml_L25/Gln-tRNA_synth_b-brl. 2 hits. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K01886.
PANTHER	PTHR10119. Glu_tRNA-synt_1c. 1 hit.
Pfam	PF00749. tRNA-synt_1c. 1 hit. PF03950. tRNA-synt_1c_C. 1 hit. PF04558. tRNA_synt_1c_R1. 1 hit. PF04557. tRNA_synt_1c_R2. 1 hit. [Graphical view]
PRINTS	PR00987. TRNASYNTHGLU.
SUPFAM	SSF50715. Ribosomal_L25rel. 1 hit.
TIGRFAMs	TIGR00440. GlnS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...
Other
SOURCE	Search...

Entry information

Entry name

Q8BML9_MOUSE

Accession

Primary (citable) accession number: Q8BML9

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	November 16, 2011
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)