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Protein
Submitted name:

Protein Tgm6

Gene

Tgm6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei274 – 2741UniRule annotation
Active sitei333 – 3331UniRule annotation
Active sitei356 – 3561UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Tgm6Imported
Submitted name:
Transglutaminase 6Imported
Gene namesi
Name:Tgm6Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:3044321. Tgm6.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiQ8BM11. baseline.
GenevestigatoriQ8BM11.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000028888.

Structurei

3D structure databases

ProteinModelPortaliQ8BM11.
SMRiQ8BM11. Positions 2-703.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119108.
HOVERGENiHBG004342.
KOiK05624.
OMAiTWLWHED.
OrthoDBiEOG7WT40M.
PhylomeDBiQ8BM11.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BM11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGVRITKVD WQHSKNGAAH HTQDYPCSEL VVRRGQLFSL TLDLSRVLDS
60 70 80 90 100
EEALIFTVET GPHASEALHT KAVFQTAELE IGDTWTAAKE EQTENTITVS
110 120 130 140 150
LSSPSNAVIG RYLLSVRPSS RRKHSDRKLG QFILLFNPWC PEDDVFLDSE
160 170 180 190 200
EERQEYVLND SGVIFRGVEK HIRAQGWNYG QFEEDILNIC LSILDRSPSH
210 220 230 240 250
QEDPATDVSH RHDPVYVTRI ISAMVNSNND RGVVQGQWQG KYGGGTNPLN
260 270 280 290 300
WRGSVAILQK WFKGRYKPVK YGQCWVFAGV MCTVLRCLGI ATRVVSNFNS
310 320 330 340 350
AHDTDGNLSV DKYVDSYGRT LEDLTEDSMW NFHVWNESWF ARQDLGPSYD
360 370 380 390 400
GWQVLDATPQ EESEGMFRCG PASVTAIREG DVHLAHDGPF VFAEVNADYI
410 420 430 440 450
TWLWHEDKRR ERVYSDTKKI GRCISTKAVG SDSRVDITGL YKYPEGSRKE
460 470 480 490 500
RQVYSKAVKK LLSVEAWGRR RRIRRASVRG VWRDDLLEPV TKPSITGKFK
510 520 530 540 550
VLEPPVLGQD LKLALCLTNL TARAQRVRVN VSGATILYTR KPVAEILRES
560 570 580 590 600
HTVKLGPLEE KKIPVTISYS QYKGDLTEDK KILLAAMCLV SKGEKLLVEK
610 620 630 640 650
DITLEDFITI KVLGPAVVGV TVTVEVLVIN PLSESVKDCV LMVEGSGLLQ
660 670 680 690 700
GQLSIEVPSL QPQEKALIQF NITPSKSGPR QLQVDLVSSQ FPDIKGFVII

HVATAK
Length:706
Mass (Da):79,209
Last modified:March 1, 2003 - v1
Checksum:iAA88FFADE97DDAF6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL833804 Genomic DNA. No translation available.
BC112420 mRNA. Translation: AAI12421.1.
AK037229 mRNA. Translation: BAC29768.1.
RefSeqiNP_001276676.1. NM_001289747.1.
NP_001276677.1. NM_001289748.1.
NP_001276678.1. NM_001289749.1.
NP_808394.1. NM_177726.4.
UniGeneiMm.83437.

Genome annotation databases

EnsembliENSMUST00000028888; ENSMUSP00000028888; ENSMUSG00000027403.
GeneIDi241636.
KEGGimmu:241636.
UCSCiuc008mii.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL833804 Genomic DNA. No translation available.
BC112420 mRNA. Translation: AAI12421.1.
AK037229 mRNA. Translation: BAC29768.1.
RefSeqiNP_001276676.1. NM_001289747.1.
NP_001276677.1. NM_001289748.1.
NP_001276678.1. NM_001289749.1.
NP_808394.1. NM_177726.4.
UniGeneiMm.83437.

3D structure databases

ProteinModelPortaliQ8BM11.
SMRiQ8BM11. Positions 2-703.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000028888.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000028888; ENSMUSP00000028888; ENSMUSG00000027403.
GeneIDi241636.
KEGGimmu:241636.
UCSCiuc008mii.1. mouse.

Organism-specific databases

CTDi343641.
MGIiMGI:3044321. Tgm6.

Phylogenomic databases

GeneTreeiENSGT00760000119108.
HOVERGENiHBG004342.
KOiK05624.
OMAiTWLWHED.
OrthoDBiEOG7WT40M.
PhylomeDBiQ8BM11.
TreeFamiTF324278.

Miscellaneous databases

NextBioi385103.
PROiQ8BM11.
SOURCEiSearch...

Gene expression databases

ExpressionAtlasiQ8BM11. baseline.
GenevestigatoriQ8BM11.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: SkinImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: SkinImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: SkinImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: SkinImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: SkinImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: SkinImported.
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PCR rescued clonesImported.
  8. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: SkinImported.
  9. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: SkinImported.
  10. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  11. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ8BM11_MOUSE
AccessioniPrimary (citable) accession number: Q8BM11
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: May 27, 2015
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.