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Q8BM11 (Q8BM11_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
Protein Tgm6 Ensembl ENSMUSP00000028888
Submitted name:
Transglutaminase 6 EMBL AAI12421.1
Gene names
Name:Tgm6 MGI 3044321 Ensembl ENSMUSP00000028888
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length706 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Cofactor

Binds 1 calcium ion per subunit By similarity. PIRSR PIRSR000459-2

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2741 By similarity PIRSR PIRSR000459-1
Active site3331 By similarity PIRSR PIRSR000459-1
Active site3561 By similarity PIRSR PIRSR000459-1
Metal binding3961Calcium By similarity PIRSR PIRSR000459-2
Metal binding3981Calcium By similarity PIRSR PIRSR000459-2
Metal binding4451Calcium By similarity PIRSR PIRSR000459-2
Metal binding4501Calcium By similarity PIRSR PIRSR000459-2

Sequences

Sequence LengthMass (Da)Tools
Q8BM11 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: AA88FFADE97DDAF6

FASTA70679,209
        10         20         30         40         50         60 
MAGVRITKVD WQHSKNGAAH HTQDYPCSEL VVRRGQLFSL TLDLSRVLDS EEALIFTVET 

        70         80         90        100        110        120 
GPHASEALHT KAVFQTAELE IGDTWTAAKE EQTENTITVS LSSPSNAVIG RYLLSVRPSS 

       130        140        150        160        170        180 
RRKHSDRKLG QFILLFNPWC PEDDVFLDSE EERQEYVLND SGVIFRGVEK HIRAQGWNYG 

       190        200        210        220        230        240 
QFEEDILNIC LSILDRSPSH QEDPATDVSH RHDPVYVTRI ISAMVNSNND RGVVQGQWQG 

       250        260        270        280        290        300 
KYGGGTNPLN WRGSVAILQK WFKGRYKPVK YGQCWVFAGV MCTVLRCLGI ATRVVSNFNS 

       310        320        330        340        350        360 
AHDTDGNLSV DKYVDSYGRT LEDLTEDSMW NFHVWNESWF ARQDLGPSYD GWQVLDATPQ 

       370        380        390        400        410        420 
EESEGMFRCG PASVTAIREG DVHLAHDGPF VFAEVNADYI TWLWHEDKRR ERVYSDTKKI 

       430        440        450        460        470        480 
GRCISTKAVG SDSRVDITGL YKYPEGSRKE RQVYSKAVKK LLSVEAWGRR RRIRRASVRG 

       490        500        510        520        530        540 
VWRDDLLEPV TKPSITGKFK VLEPPVLGQD LKLALCLTNL TARAQRVRVN VSGATILYTR 

       550        560        570        580        590        600 
KPVAEILRES HTVKLGPLEE KKIPVTISYS QYKGDLTEDK KILLAAMCLV SKGEKLLVEK 

       610        620        630        640        650        660 
DITLEDFITI KVLGPAVVGV TVTVEVLVIN PLSESVKDCV LMVEGSGLLQ GQLSIEVPSL 

       670        680        690        700 
QPQEKALIQF NITPSKSGPR QLQVDLVSSQ FPDIKGFVII HVATAK

« Hide

References

« Hide 'large scale' references
[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC29768.1.
Tissue: Skin EMBL BAC29768.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC29768.1.
Tissue: Skin EMBL BAC29768.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC29768.1.
Tissue: Skin EMBL BAC29768.1.
[4]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC29768.1.
Tissue: Skin EMBL BAC29768.1.
[5]Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P., Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W., Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T., Hori F., Imotani K. expand/collapse author list , Ishii Y., Itoh M., Kagawa I., Kasukawa T., Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M., Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y., Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H., Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M., Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T., Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.
Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC29768.1.
Tissue: Skin EMBL BAC29768.1.
[6]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC29768.1.
Tissue: Skin EMBL BAC29768.1.
[7]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. expand/collapse author list , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: PCR rescued clones EMBL AAI12421.1.
[8]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC29768.1.
Tissue: Skin EMBL BAC29768.1.
[9]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAC29768.1.
Tissue: Skin EMBL BAC29768.1.
[10]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000028888.
[11]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000028888.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL833804 Genomic DNA. No translation available.
BC112420 mRNA. Translation: AAI12421.1.
AK037229 mRNA. Translation: BAC29768.1.
IPIIPI00468609.
RefSeqNP_808394.1. NM_177726.3.
UniGeneMm.83437.

3D structure databases

HSSPHSSP built from PDB template 1KV3 based on UniProtKB P21980.
SMRQ8BM11. Positions 2-703.
ModBaseSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000028888.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000028888; ENSMUSP00000028888; ENSMUSG00000027403.
GeneID241636.
KEGGmmu:241636.
UCSCuc008mii.1. mouse.

Organism-specific databases

CTD343641.
MGIMGI:3044321. Tgm6.

Phylogenomic databases

GeneTreeENSGT00690000101863.
HOVERGENHBG004342.
InParanoidQ8BM11.
KOK05624.
OMAEDSMWNF.

Gene expression databases

GenevestigatorQ8BM11.

Family and domain databases

Gene3D2.60.40.10. 3 hits.
InterProIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERPTHR11590. PTHR11590. 1 hit.
PfamPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFPIRSF000459. TGM_EBP42. 1 hit.
SMARTSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMSSF81296. Ig_E-set. 1 hit.
SSF49309. Transglut_C. 2 hits.
PROSITEPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio385103.
SOURCESearch...

Entry information

Entry nameQ8BM11_MOUSE
AccessionPrimary (citable) accession number: Q8BM11
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: April 3, 2013
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info