Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8BM11

- Q8BM11_MOUSE

UniProt

Q8BM11 - Q8BM11_MOUSE

Protein
Submitted name:

Protein Tgm6

Gene

Tgm6

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 97 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Cofactori

    Binds 1 calcium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei274 – 2741UniRule annotation
    Active sitei333 – 3331UniRule annotation
    Active sitei356 – 3561UniRule annotation
    Metal bindingi396 – 3961CalciumUniRule annotation
    Metal bindingi398 – 3981CalciumUniRule annotation
    Metal bindingi445 – 4451CalciumUniRule annotation
    Metal bindingi450 – 4501CalciumUniRule annotation

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

    GO - Biological processi

    1. peptide cross-linking Source: InterPro

    Keywords - Ligandi

    CalciumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein Tgm6Imported
    Submitted name:
    Transglutaminase 6Imported
    Gene namesi
    Name:Tgm6Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 2

    Organism-specific databases

    MGIiMGI:3044321. Tgm6.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: MGI

    Expressioni

    Gene expression databases

    GenevestigatoriQ8BM11.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000028888.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00740000115034.
    HOVERGENiHBG004342.
    InParanoidiQ8BM11.
    KOiK05624.
    OMAiWRGSVAI.
    OrthoDBiEOG7WT40M.
    TreeFamiTF324278.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view]
    PANTHERiPTHR11590. PTHR11590. 1 hit.
    PfamiPF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
    SMARTiSM00460. TGc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8BM11-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAGVRITKVD WQHSKNGAAH HTQDYPCSEL VVRRGQLFSL TLDLSRVLDS    50
    EEALIFTVET GPHASEALHT KAVFQTAELE IGDTWTAAKE EQTENTITVS 100
    LSSPSNAVIG RYLLSVRPSS RRKHSDRKLG QFILLFNPWC PEDDVFLDSE 150
    EERQEYVLND SGVIFRGVEK HIRAQGWNYG QFEEDILNIC LSILDRSPSH 200
    QEDPATDVSH RHDPVYVTRI ISAMVNSNND RGVVQGQWQG KYGGGTNPLN 250
    WRGSVAILQK WFKGRYKPVK YGQCWVFAGV MCTVLRCLGI ATRVVSNFNS 300
    AHDTDGNLSV DKYVDSYGRT LEDLTEDSMW NFHVWNESWF ARQDLGPSYD 350
    GWQVLDATPQ EESEGMFRCG PASVTAIREG DVHLAHDGPF VFAEVNADYI 400
    TWLWHEDKRR ERVYSDTKKI GRCISTKAVG SDSRVDITGL YKYPEGSRKE 450
    RQVYSKAVKK LLSVEAWGRR RRIRRASVRG VWRDDLLEPV TKPSITGKFK 500
    VLEPPVLGQD LKLALCLTNL TARAQRVRVN VSGATILYTR KPVAEILRES 550
    HTVKLGPLEE KKIPVTISYS QYKGDLTEDK KILLAAMCLV SKGEKLLVEK 600
    DITLEDFITI KVLGPAVVGV TVTVEVLVIN PLSESVKDCV LMVEGSGLLQ 650
    GQLSIEVPSL QPQEKALIQF NITPSKSGPR QLQVDLVSSQ FPDIKGFVII 700
    HVATAK 706
    Length:706
    Mass (Da):79,209
    Last modified:March 1, 2003 - v1
    Checksum:iAA88FFADE97DDAF6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL833804 Genomic DNA. No translation available.
    BC112420 mRNA. Translation: AAI12421.1.
    AK037229 mRNA. Translation: BAC29768.1.
    RefSeqiNP_001276676.1. NM_001289747.1.
    NP_001276677.1. NM_001289748.1.
    NP_001276678.1. NM_001289749.1.
    NP_808394.1. NM_177726.4.
    UniGeneiMm.83437.

    Genome annotation databases

    EnsembliENSMUST00000028888; ENSMUSP00000028888; ENSMUSG00000027403.
    GeneIDi241636.
    KEGGimmu:241636.
    UCSCiuc008mii.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL833804 Genomic DNA. No translation available.
    BC112420 mRNA. Translation: AAI12421.1 .
    AK037229 mRNA. Translation: BAC29768.1 .
    RefSeqi NP_001276676.1. NM_001289747.1.
    NP_001276677.1. NM_001289748.1.
    NP_001276678.1. NM_001289749.1.
    NP_808394.1. NM_177726.4.
    UniGenei Mm.83437.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000028888.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000028888 ; ENSMUSP00000028888 ; ENSMUSG00000027403 .
    GeneIDi 241636.
    KEGGi mmu:241636.
    UCSCi uc008mii.1. mouse.

    Organism-specific databases

    CTDi 343641.
    MGIi MGI:3044321. Tgm6.

    Phylogenomic databases

    GeneTreei ENSGT00740000115034.
    HOVERGENi HBG004342.
    InParanoidi Q8BM11.
    KOi K05624.
    OMAi WRGSVAI.
    OrthoDBi EOG7WT40M.
    TreeFami TF324278.

    Miscellaneous databases

    NextBioi 385103.
    PROi Q8BM11.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q8BM11.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view ]
    PANTHERi PTHR11590. PTHR11590. 1 hit.
    Pfami PF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
    SMARTi SM00460. TGc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: SkinImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: SkinImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: SkinImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: SkinImported.
    5. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: SkinImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: SkinImported.
    7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: PCR rescued clonesImported.
    8. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: SkinImported.
    9. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: SkinImported.
    10. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    11. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ8BM11_MOUSE
    AccessioniPrimary (citable) accession number: Q8BM11
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 97 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3