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Protein
Submitted name:

Transglutaminase 6

Gene

Tgm6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Cofactori

Ca2+UniRule annotationNote: Binds 1 Ca2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei274UniRule annotation1
Active sitei333UniRule annotation1
Active sitei356UniRule annotation1
Metal bindingi396CalciumUniRule annotation1
Metal bindingi398CalciumUniRule annotation1
Metal bindingi445CalciumUniRule annotation1
Metal bindingi450CalciumUniRule annotation1

GO - Molecular functioni

  • metal ion binding Source: UniProtKB-KW
  • protein-glutamine gamma-glutamyltransferase activity Source: MGI

GO - Biological processi

Keywordsi

LigandCalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Transglutaminase 6Imported
Gene namesi
Name:Tgm6Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:3044321 Tgm6

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSMUSG00000027403

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000028888

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini266 – 359TGcInterPro annotationAdd BLAST94

Phylogenomic databases

eggNOGiENOG410IFMV Eukaryota
ENOG410XQEZ LUCA
GeneTreeiENSGT00760000119108
HOVERGENiHBG004342
KOiK05624
OMAiNESWFAR
OrthoDBiEOG091G030K
TreeFamiTF324278

Family and domain databases

Gene3Di2.60.40.10, 3 hits
3.90.260.10, 1 hit
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002931 Transglutaminase-like
IPR036985 Transglutaminase-like_sf
IPR023608 Transglutaminase_animal
IPR013808 Transglutaminase_AS
IPR008958 Transglutaminase_C
IPR036238 Transglutaminase_C_sf
IPR001102 Transglutaminase_N
PfamiView protein in Pfam
PF00927 Transglut_C, 2 hits
PF01841 Transglut_core, 1 hit
PF00868 Transglut_N, 1 hit
PIRSFiPIRSF000459 TGM_EBP42, 1 hit
SMARTiView protein in SMART
SM00460 TGc, 1 hit
SUPFAMiSSF49309 SSF49309, 2 hits
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS00547 TRANSGLUTAMINASES, 1 hit

Sequencei

Sequence statusi: Complete.

Q8BM11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGVRITKVD WQHSKNGAAH HTQDYPCSEL VVRRGQLFSL TLDLSRVLDS
60 70 80 90 100
EEALIFTVET GPHASEALHT KAVFQTAELE IGDTWTAAKE EQTENTITVS
110 120 130 140 150
LSSPSNAVIG RYLLSVRPSS RRKHSDRKLG QFILLFNPWC PEDDVFLDSE
160 170 180 190 200
EERQEYVLND SGVIFRGVEK HIRAQGWNYG QFEEDILNIC LSILDRSPSH
210 220 230 240 250
QEDPATDVSH RHDPVYVTRI ISAMVNSNND RGVVQGQWQG KYGGGTNPLN
260 270 280 290 300
WRGSVAILQK WFKGRYKPVK YGQCWVFAGV MCTVLRCLGI ATRVVSNFNS
310 320 330 340 350
AHDTDGNLSV DKYVDSYGRT LEDLTEDSMW NFHVWNESWF ARQDLGPSYD
360 370 380 390 400
GWQVLDATPQ EESEGMFRCG PASVTAIREG DVHLAHDGPF VFAEVNADYI
410 420 430 440 450
TWLWHEDKRR ERVYSDTKKI GRCISTKAVG SDSRVDITGL YKYPEGSRKE
460 470 480 490 500
RQVYSKAVKK LLSVEAWGRR RRIRRASVRG VWRDDLLEPV TKPSITGKFK
510 520 530 540 550
VLEPPVLGQD LKLALCLTNL TARAQRVRVN VSGATILYTR KPVAEILRES
560 570 580 590 600
HTVKLGPLEE KKIPVTISYS QYKGDLTEDK KILLAAMCLV SKGEKLLVEK
610 620 630 640 650
DITLEDFITI KVLGPAVVGV TVTVEVLVIN PLSESVKDCV LMVEGSGLLQ
660 670 680 690 700
GQLSIEVPSL QPQEKALIQF NITPSKSGPR QLQVDLVSSQ FPDIKGFVII

HVATAK
Length:706
Mass (Da):79,209
Last modified:March 1, 2003 - v1
Checksum:iAA88FFADE97DDAF6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL833804 Genomic DNA No translation available.
BC112420 mRNA Translation: AAI12421.1
AK037229 mRNA Translation: BAC29768.1
RefSeqiNP_001276676.1, NM_001289747.1
NP_001276677.1, NM_001289748.1
NP_001276678.1, NM_001289749.1
NP_808394.1, NM_177726.4
UniGeneiMm.83437

Genome annotation databases

EnsembliENSMUST00000028888; ENSMUSP00000028888; ENSMUSG00000027403
GeneIDi241636
KEGGimmu:241636
UCSCiuc008mii.2 mouse

Similar proteinsi

Entry informationi

Entry nameiQ8BM11_MOUSE
AccessioniPrimary (citable) accession number: Q8BM11
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: April 25, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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