Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8BL95

- CU059_MOUSE

UniProt

Q8BL95 - CU059_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

UPF0769 protein C21orf59 homolog

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

May play a role for motile cilia function, possibly by acting on dynein arm assembly.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0769 protein C21orf59 homolog
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 16

Organism-specific databases

MGIiMGI:1915251. 1110004E09Rik.

Subcellular locationi

Cytoplasm By similarity
Note: Partially colocalized with SASS6 in cytoplasmic puncta, suggesting a centrosomal localization.By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 290290UPF0769 protein C21orf59 homologPRO_0000424911Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Cross-linki210 – 210Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)By similarity

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

MaxQBiQ8BL95.
PRIDEiQ8BL95.

2D gel databases

REPRODUCTION-2DPAGEIPI00281363.

Expressioni

Gene expression databases

ExpressionAtlasiQ8BL95. baseline and differential.
GenevestigatoriQ8BL95.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000023694.

Structurei

3D structure databases

ProteinModelPortaliQ8BL95.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0769 family.Curated

Phylogenomic databases

eggNOGiNOG74285.
GeneTreeiENSGT00390000006278.
HOGENOMiHOG000282965.
HOVERGENiHBG051236.
InParanoidiQ8BL95.
OMAiKKGQGAP.
OrthoDBiEOG4NS3C2.
PhylomeDBiQ8BL95.
TreeFamiTF323482.

Family and domain databases

InterProiIPR021298. DUF2870.
[Graphical view]
PfamiPF11069. DUF2870. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BL95-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVVLHVKRGD ESQFLLQAPG STELEELTAQ VARVYNGRLK VHRLCSEMEE
60 70 80 90 100
LAEHGVFLPP NMQGLTDEQI EELKLKDEWG EKCVPSGGSV FTKDEIGRRN
110 120 130 140 150
GQAPNEKMKQ VLKKTVEEAK AIVSKKQVEA GVFVTMEMVK DALDQLRGAV
160 170 180 190 200
MIVYPMGLPP YDPIRMEFEN KEDLSGTQAA LEVIQESEAQ LWWAAKELRR
210 220 230 240 250
TKKLSDYVGK NEKTKIIVKI QQRGQGAPAR EPVISSEEHK QLMLFYHRRQ
260 270 280 290
EELKKLEEND DDSCLNSPWA DNTALKRHFH GVKDIKWRPR
Length:290
Mass (Da):33,190
Last modified:March 1, 2003 - v1
Checksum:iFC6329D384D3CFE9
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti59 – 591P → H in AAH19533. (PubMed:15489334)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK045905 mRNA. Translation: BAC32526.1.
AC134560 Genomic DNA. No translation available.
CH466602 Genomic DNA. Translation: EDL03846.1.
BC019533 mRNA. Translation: AAH19533.1.
CCDSiCCDS28321.1.
RefSeqiNP_080778.2. NM_026502.2.
UniGeneiMm.45374.

Genome annotation databases

EnsembliENSMUST00000023694; ENSMUSP00000023694; ENSMUSG00000022972.
GeneIDi68001.
KEGGimmu:68001.
UCSCiuc007zwt.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK045905 mRNA. Translation: BAC32526.1 .
AC134560 Genomic DNA. No translation available.
CH466602 Genomic DNA. Translation: EDL03846.1 .
BC019533 mRNA. Translation: AAH19533.1 .
CCDSi CCDS28321.1.
RefSeqi NP_080778.2. NM_026502.2.
UniGenei Mm.45374.

3D structure databases

ProteinModelPortali Q8BL95.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000023694.

2D gel databases

REPRODUCTION-2DPAGE IPI00281363.

Proteomic databases

MaxQBi Q8BL95.
PRIDEi Q8BL95.

Protocols and materials databases

DNASUi 68001.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000023694 ; ENSMUSP00000023694 ; ENSMUSG00000022972 .
GeneIDi 68001.
KEGGi mmu:68001.
UCSCi uc007zwt.2. mouse.

Organism-specific databases

MGIi MGI:1915251. 1110004E09Rik.

Phylogenomic databases

eggNOGi NOG74285.
GeneTreei ENSGT00390000006278.
HOGENOMi HOG000282965.
HOVERGENi HBG051236.
InParanoidi Q8BL95.
OMAi KKGQGAP.
OrthoDBi EOG4NS3C2.
PhylomeDBi Q8BL95.
TreeFami TF323482.

Miscellaneous databases

NextBioi 326180.

Gene expression databases

ExpressionAtlasi Q8BL95. baseline and differential.
Genevestigatori Q8BL95.

Family and domain databases

InterProi IPR021298. DUF2870.
[Graphical view ]
Pfami PF11069. DUF2870. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Corpora quadrigemina.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N.
    Tissue: Salivary gland.

Entry informationi

Entry nameiCU059_MOUSE
AccessioniPrimary (citable) accession number: Q8BL95
Secondary accession number(s): Q8VCL7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 22, 2014
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

External Data

Dasty 3