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Protein

Probable G-protein coupled receptor 150

Gene

Gpr150

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Orphan receptor.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Enzyme and pathway databases

ReactomeiR-MMU-418555. G alpha (s) signalling events.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable G-protein coupled receptor 150
Alternative name(s):
G-protein coupled receptor PGR11
Gene namesi
Name:Gpr150
Synonyms:Pgr11
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:2441872. Gpr150.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 33ExtracellularSequence analysis
Transmembranei4 – 2421Helical; Name=1Sequence analysisAdd
BLAST
Topological domaini25 – 5026CytoplasmicSequence analysisAdd
BLAST
Transmembranei51 – 7121Helical; Name=2Sequence analysisAdd
BLAST
Topological domaini72 – 8918ExtracellularSequence analysisAdd
BLAST
Transmembranei90 – 11021Helical; Name=3Sequence analysisAdd
BLAST
Topological domaini111 – 17060CytoplasmicSequence analysisAdd
BLAST
Transmembranei171 – 19121Helical; Name=4Sequence analysisAdd
BLAST
Topological domaini192 – 23039ExtracellularSequence analysisAdd
BLAST
Transmembranei231 – 25121Helical; Name=5Sequence analysisAdd
BLAST
Topological domaini252 – 28635CytoplasmicSequence analysisAdd
BLAST
Transmembranei287 – 30721Helical; Name=6Sequence analysisAdd
BLAST
Topological domaini308 – 32720ExtracellularSequence analysisAdd
BLAST
Transmembranei328 – 34821Helical; Name=7Sequence analysisAdd
BLAST
Topological domaini349 – 42779CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 427427Probable G-protein coupled receptor 150PRO_0000069631Add
BLAST

Proteomic databases

PaxDbiQ8BL07.
PRIDEiQ8BL07.

PTM databases

PhosphoSiteiQ8BL07.

Expressioni

Gene expression databases

BgeeiQ8BL07.
CleanExiMM_GPR150.
GenevisibleiQ8BL07. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000049592.

Structurei

3D structure databases

ProteinModelPortaliQ8BL07.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi411 – 42010Poly-Pro

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000119156.
HOGENOMiHOG000112773.
HOVERGENiHBG051786.
InParanoidiQ8BL07.
KOiK08434.
OMAiWHLQVYA.
OrthoDBiEOG78WKS0.
PhylomeDBiQ8BL07.
TreeFamiTF106499.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BL07-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDPFSLAIL NPASNLSVPT QPSWSLNLTS EQGASVPGPH SPPRGPPSHR
60 70 80 90 100
IHLVFLGIIL VAAVAGNTTV LCRLCGGSSG PWPGPKRRKM DFLLVQLAAA
110 120 130 140 150
DLYASGGTAL SQLAWELLGD PRPALGDLAC RLSHLLQASG RGASAHLVAL
160 170 180 190 200
IALERQLAVR IPQGPQLPAR ALAALSWLLA LLLALPPTFV VRWDAPPSST
210 220 230 240 250
ANAWPGKHCC RGIFAPLPRW HLQVYALYEA IVGFAAPVAL LGFSCGHLLC
260 270 280 290 300
VWWQRGSQAP VARMPWSPSM ARASLPSALP QAKVQSLKMS LALALLFVGC
310 320 330 340 350
DLPYFAARLA AAWSSKPAGD WERESLVAAM RVLEVANSAI NPLIYLFFQA
360 370 380 390 400
GDCRLWRRLR RRLGVLCCVR EEEADISEWA GDHQALHRHR WPHPHYHHAR
410 420
REERNQGCLR PPPPRPRPPP CSCESAF
Length:427
Mass (Da):46,519
Last modified:March 1, 2003 - v1
Checksum:i816A8E34CADD2436
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK047609 mRNA. Translation: BAC33097.1.
BC118612 mRNA. Translation: AAI18613.1.
BC118614 mRNA. Translation: AAI18615.1.
AY255541 mRNA. Translation: AAO85053.1.
CCDSiCCDS26655.1.
RefSeqiNP_780704.1. NM_175495.2.
UniGeneiMm.167172.

Genome annotation databases

EnsembliENSMUST00000056130; ENSMUSP00000049592; ENSMUSG00000045509.
GeneIDi238725.
KEGGimmu:238725.
UCSCiuc007rgg.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK047609 mRNA. Translation: BAC33097.1.
BC118612 mRNA. Translation: AAI18613.1.
BC118614 mRNA. Translation: AAI18615.1.
AY255541 mRNA. Translation: AAO85053.1.
CCDSiCCDS26655.1.
RefSeqiNP_780704.1. NM_175495.2.
UniGeneiMm.167172.

3D structure databases

ProteinModelPortaliQ8BL07.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000049592.

Protein family/group databases

GPCRDBiSearch...

PTM databases

PhosphoSiteiQ8BL07.

Proteomic databases

PaxDbiQ8BL07.
PRIDEiQ8BL07.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000056130; ENSMUSP00000049592; ENSMUSG00000045509.
GeneIDi238725.
KEGGimmu:238725.
UCSCiuc007rgg.1. mouse.

Organism-specific databases

CTDi285601.
MGIiMGI:2441872. Gpr150.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000119156.
HOGENOMiHOG000112773.
HOVERGENiHBG051786.
InParanoidiQ8BL07.
KOiK08434.
OMAiWHLQVYA.
OrthoDBiEOG78WKS0.
PhylomeDBiQ8BL07.
TreeFamiTF106499.

Enzyme and pathway databases

ReactomeiR-MMU-418555. G alpha (s) signalling events.

Miscellaneous databases

NextBioi383876.
PROiQ8BL07.
SOURCEiSearch...

Gene expression databases

BgeeiQ8BL07.
CleanExiMM_GPR150.
GenevisibleiQ8BL07. MM.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Corpus striatum.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 9-109.

Entry informationi

Entry nameiGP150_MOUSE
AccessioniPrimary (citable) accession number: Q8BL07
Secondary accession number(s): Q147V7, Q80UD4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: March 1, 2003
Last modified: February 17, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.