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Q8BL07 (GP150_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable G-protein coupled receptor 150
Alternative name(s):
G-protein coupled receptor PGR11
Gene names
Name:Gpr150
Synonyms:Pgr11
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length427 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Orphan receptor.

Subcellular location

Cell membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the G-protein coupled receptor 1 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 427427Probable G-protein coupled receptor 150
PRO_0000069631

Regions

Topological domain1 – 33Extracellular Potential
Transmembrane4 – 2421Helical; Name=1; Potential
Topological domain25 – 5026Cytoplasmic Potential
Transmembrane51 – 7121Helical; Name=2; Potential
Topological domain72 – 8918Extracellular Potential
Transmembrane90 – 11021Helical; Name=3; Potential
Topological domain111 – 17060Cytoplasmic Potential
Transmembrane171 – 19121Helical; Name=4; Potential
Topological domain192 – 23039Extracellular Potential
Transmembrane231 – 25121Helical; Name=5; Potential
Topological domain252 – 28635Cytoplasmic Potential
Transmembrane287 – 30721Helical; Name=6; Potential
Topological domain308 – 32720Extracellular Potential
Transmembrane328 – 34821Helical; Name=7; Potential
Topological domain349 – 42779Cytoplasmic Potential
Compositional bias411 – 42010Poly-Pro

Sequences

Sequence LengthMass (Da)Tools
Q8BL07 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 816A8E34CADD2436

FASTA42746,519
        10         20         30         40         50         60 
MEDPFSLAIL NPASNLSVPT QPSWSLNLTS EQGASVPGPH SPPRGPPSHR IHLVFLGIIL 

        70         80         90        100        110        120 
VAAVAGNTTV LCRLCGGSSG PWPGPKRRKM DFLLVQLAAA DLYASGGTAL SQLAWELLGD 

       130        140        150        160        170        180 
PRPALGDLAC RLSHLLQASG RGASAHLVAL IALERQLAVR IPQGPQLPAR ALAALSWLLA 

       190        200        210        220        230        240 
LLLALPPTFV VRWDAPPSST ANAWPGKHCC RGIFAPLPRW HLQVYALYEA IVGFAAPVAL 

       250        260        270        280        290        300 
LGFSCGHLLC VWWQRGSQAP VARMPWSPSM ARASLPSALP QAKVQSLKMS LALALLFVGC 

       310        320        330        340        350        360 
DLPYFAARLA AAWSSKPAGD WERESLVAAM RVLEVANSAI NPLIYLFFQA GDCRLWRRLR 

       370        380        390        400        410        420 
RRLGVLCCVR EEEADISEWA GDHQALHRHR WPHPHYHHAR REERNQGCLR PPPPRPRPPP 


CSCESAF

« Hide

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Corpus striatum.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[3]"The G protein-coupled receptor repertoires of human and mouse."
Vassilatis D.K., Hohmann J.G., Zeng H., Li F., Ranchalis J.E., Mortrud M.T., Brown A., Rodriguez S.S., Weller J.R., Wright A.C., Bergmann J.E., Gaitanaris G.A.
Proc. Natl. Acad. Sci. U.S.A. 100:4903-4908(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 9-109.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AK047609 mRNA. Translation: BAC33097.1.
BC118612 mRNA. Translation: AAI18613.1.
BC118614 mRNA. Translation: AAI18615.1.
AY255541 mRNA. Translation: AAO85053.1.
IPIIPI00222651.
RefSeqNP_780704.1. NM_175495.2.
UniGeneMm.167172.

3D structure databases

ProteinModelPortalQ8BL07.
SMRQ8BL07. Positions 54-345.
ModBaseSearch...

Protein family/group databases

GPCRDBSearch...

PTM databases

PhosphoSiteQ8BL07.

Proteomic databases

PRIDEQ8BL07.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000056130; ENSMUSP00000049592; ENSMUSG00000045509.
GeneID238725.
KEGGmmu:238725.
UCSCuc007rgg.1. mouse.

Organism-specific databases

CTD285601.
MGIMGI:2441872. Gpr150.

Phylogenomic databases

eggNOGNOG326444.
GeneTreeENSGT00660000095405.
HOGENOMHOG000112773.
HOVERGENHBG051786.
InParanoidQ147V7.
KOK08434.
OMALPCSCES.
OrthoDBEOG4ZCT4X.

Gene expression databases

BgeeQ8BL07.
CleanExMM_GPR150.
GenevestigatorQ8BL07.
GermOnlineENSMUSG00000045509. Mus musculus.

Family and domain databases

InterProIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PANTHERPTHR24236. PTHR24236. 1 hit.
PfamPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSPR00237. GPCRRHODOPSN.
PROSITEPS00237. G_PROTEIN_RECEP_F1_1. False negative.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio383876.
SOURCESearch...

Entry information

Entry nameGP150_MOUSE
AccessionPrimary (citable) accession number: Q8BL07
Secondary accession number(s): Q147V7, Q80UD4
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: March 1, 2003
Last modified: May 1, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

7-transmembrane G-linked receptors

List of 7-transmembrane G-linked receptor entries

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents