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Q8BKG3

- PTK7_MOUSE

UniProt

Q8BKG3 - PTK7_MOUSE

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Protein

Inactive tyrosine-protein kinase 7

Gene

Ptk7

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.3 Publications

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei613 – 6142Cleavage; by MMP14By similarity

GO - Molecular functioni

  1. transferase activity, transferring phosphorus-containing groups Source: InterPro

GO - Biological processi

  1. actin cytoskeleton reorganization Source: Ensembl
  2. axis elongation Source: MGI
  3. canonical Wnt signaling pathway Source: Ensembl
  4. cell adhesion Source: UniProtKB-KW
  5. cell migration Source: Ensembl
  6. cellular response to retinoic acid Source: Ensembl
  7. cochlea morphogenesis Source: MGI
  8. convergent extension Source: MGI
  9. establishment of epithelial cell apical/basal polarity Source: MGI
  10. establishment of planar polarity Source: MGI
  11. lung-associated mesenchyme development Source: MGI
  12. neural tube closure Source: MGI
  13. planar cell polarity pathway involved in neural tube closure Source: MGI
  14. positive regulation of neuron projection development Source: Ensembl
  15. wound healing Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Receptor

Keywords - Biological processi

Cell adhesion, Wnt signaling pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Inactive tyrosine-protein kinase 7
Alternative name(s):
Protein chuzhoi
Protein-tyrosine kinase 7
Pseudo tyrosine kinase receptor 7
Tyrosine-protein kinase-like 7
Gene namesi
Name:Ptk7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 17

Organism-specific databases

MGIiMGI:1918711. Ptk7.

Subcellular locationi

Membrane; Single-pass type I membrane protein. Cell junction By similarity
Note: Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells.

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini23 – 696674ExtracellularSequence AnalysisAdd
BLAST
Transmembranei697 – 71721HelicalSequence AnalysisAdd
BLAST
Topological domaini718 – 1062345CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. cell-cell junction Source: MGI
  2. integral component of membrane Source: UniProtKB-KW
  3. membrane Source: MGI
  4. plasma membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Membrane

Pathology & Biotechi

Disruption phenotypei

Mice die perinatally and display craniorachischisis, a severe form of neural tube defect in which the neural tube fails to close from the midbrain hindbrain boundary to the base of the spine. Chuzhoi mutants also display disruption of planar cell polarity in the inner ear, and defective heart and lung development.3 Publications

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence AnalysisAdd
BLAST
Chaini23 – 10621040Inactive tyrosine-protein kinase 7PRO_0000260435Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi45 ↔ 93PROSITE-ProRule annotation
Glycosylationi98 – 981N-linked (GlcNAc...)1 Publication
Glycosylationi108 – 1081N-linked (GlcNAc...)1 Publication
Disulfide bondi142 ↔ 192PROSITE-ProRule annotation
Glycosylationi176 – 1761N-linked (GlcNAc...)Sequence Analysis
Glycosylationi206 – 2061N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi238 ↔ 293PROSITE-ProRule annotation
Glycosylationi260 – 2601N-linked (GlcNAc...)Sequence Analysis
Glycosylationi275 – 2751N-linked (GlcNAc...)1 Publication
Disulfide bondi335 ↔ 383PROSITE-ProRule annotation
Glycosylationi397 – 3971N-linked (GlcNAc...)2 Publications
Disulfide bondi425 ↔ 473PROSITE-ProRule annotation
Glycosylationi455 – 4551N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi516 ↔ 562PROSITE-ProRule annotation
Glycosylationi559 – 5591N-linked (GlcNAc...)1 Publication
Disulfide bondi605 ↔ 656PROSITE-ProRule annotation
Glycosylationi638 – 6381N-linked (GlcNAc...)Sequence Analysis

Post-translational modificationi

MMP14 cleaves PTK7 between Pro-613 and Leu-614 generating an N-terminal soluble (70 kDa) fragment and a membrane C-terminal (50 kDa) fragment. Proteolysis by MMP14 regulates PTK7 function in non-canonical Wnt signaling pathway.By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

MaxQBiQ8BKG3.
PaxDbiQ8BKG3.
PRIDEiQ8BKG3.

PTM databases

PhosphoSiteiQ8BKG3.

Expressioni

Tissue specificityi

Expressed at high levels in lung and un-pregnant uterus among adult tissues, and in the tail, limbs, somites, gut and craniofacial regions among embryonic tissues.1 Publication

Gene expression databases

BgeeiQ8BKG3.
CleanExiMM_PTK7.
ExpressionAtlasiQ8BKG3. baseline.
GenevestigatoriQ8BKG3.

Interactioni

Subunit structurei

Interacts with CTNNB1.By similarity

Protein-protein interaction databases

IntActiQ8BKG3. 1 interaction.
MINTiMINT-4111157.
STRINGi10090.ENSMUSP00000043703.

Structurei

3D structure databases

ProteinModelPortaliQ8BKG3.
SMRiQ8BKG3. Positions 26-685, 794-1046.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini23 – 11290Ig-like C2-type 1Add
BLAST
Domaini120 – 21091Ig-like C2-type 2Add
BLAST
Domaini217 – 30993Ig-like C2-type 3Add
BLAST
Domaini301 – 39999Ig-like C2-type 4Add
BLAST
Domaini404 – 48986Ig-like C2-type 5Add
BLAST
Domaini495 – 57884Ig-like C2-type 6Add
BLAST
Domaini570 – 672103Ig-like C2-type 7Add
BLAST
Domaini788 – 1058271Protein kinase; inactivePROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni786 – 1062277Interaction with CTNNB1By similarityAdd
BLAST

Domaini

The protein kinase domain is predicted to be catalytically inactive.

Sequence similaritiesi

Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Immunoglobulin domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0515.
GeneTreeiENSGT00760000118818.
HOGENOMiHOG000115767.
HOVERGENiHBG008320.
InParanoidiQ8BKG3.
KOiK05127.
OMAiDGTWYRC.
OrthoDBiEOG790G1M.
PhylomeDBiQ8BKG3.
TreeFamiTF326835.

Family and domain databases

Gene3Di2.60.40.10. 7 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
IPR020635. Tyr_kinase_cat_dom.
[Graphical view]
PfamiPF07679. I-set. 5 hits.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
PRINTSiPR00109. TYRKINASE.
SMARTiSM00409. IG. 1 hit.
SM00408. IGc2. 6 hits.
SM00219. TyrKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50835. IG_LIKE. 7 hits.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8BKG3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGARPLTLLR ALLLPLLAGA QAAIVFIKEP SSQDALQGRR ALLRCEVEAP
60 70 80 90 100
DPVHVYWLLN GVPVQDTERR FAQGSSLSFA AVDRLQDSGA FQCVARDNVT
110 120 130 140 150
GEEVRSTNAS FNIKWIEAGP VVLKHPASEA EIQPQTQVTL RCHIDGHPRP
160 170 180 190 200
TYQWFRDGTP LSDDQSTHTV SSRERNLTLR PASPEHSGLY SCCAHNAFGQ
210 220 230 240 250
ACSSQNFTLS VADESFARVV LAPQDVVVAR NEEAMFHCQF SAQPPPSLQW
260 270 280 290 300
VFEDETPITN RSRPPHLRRA VVFANGSLLL TQVRPRNAGV YRCIGQGQRG
310 320 330 340 350
PPIVLEATLH LAEIEDMLPF EPRVFIAGDE ERVTCPAPQG LPTPSVWWEH
360 370 380 390 400
AGVPLPAHGR VHQKGLELVF VTIAESDTGV YTCHASNLAG QRRQDVNITV
410 420 430 440 450
ATVPTWLRKP QDSQLEEGKP GYLHCLTQAT PKPTVIWYRN QMLISEDSRF
460 470 480 490 500
EVSKNGTLRI NSVEVYDGTL YRCVSSTPAG SIEAQARVQV LEKLKFTPPP
510 520 530 540 550
QPQQCMEFDK EATVPCSATG REKPTVKWVR ADGSSLPEWV TDNAGTLHFA
560 570 580 590 600
RVTRDDAGNY TCIASNEPQG QIRAHVQLTV AVFITFKVEP ERTTVYQGHT
610 620 630 640 650
ALLRCEAQGD PKPLIQWKGK DRILDPTKLG PRMHIFQNGS LVIHDVAPED
660 670 680 690 700
SGSYTCIAGN SCNIRHTEAP LLVVDKPVME DSEGPGSPPP YKMIQTIGLS
710 720 730 740 750
VGAAVAYIIA VLGLMFYCKK RCKAKRLQKQ PEGEEPEMEC LNGGPLQNGQ
760 770 780 790 800
PSAEIQEEVA LTSLGSGPPA TNKRHSAGDR MHFPRASLQP ITTLGKSEFG
810 820 830 840 850
EVFLAKAQGV EEGATETLVL VKSLQSRDEQ QQLDFRREVE MFGKLNHANV
860 870 880 890 900
VRLLGLCREA EPHYMVLEYV DLGDLKQFLR ISKNKDEKLK SQPLSTKQKV
910 920 930 940 950
ALCSQVALGM EHLSNNRFVH KDLAARNCLI SAQRQVKVSA LGLSKDVYNS
960 970 980 990 1000
EYYHFRQAWV PLRWMSPEAV LEGDFSTKSD VWAFGVLMWE VFTHGEMPHG
1010 1020 1030 1040 1050
GQADDEVLAD LQAGKARLPQ PEGCPSKLYR LMQRCWAPNP KDRPSFSEIA
1060
STLGDSPADS KQ
Length:1,062
Mass (Da):117,532
Last modified:March 1, 2003 - v1
Checksum:i138E25198A21E6A1
GO

Sequence cautioni

The sequence AAH27800.1 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti818 – 8181L → R in BAC53806. 1 PublicationCurated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF531873 mRNA. Translation: AAQ10071.1.
AY303976 Genomic DNA. Translation: AAQ73496.1.
AK018379 mRNA. Translation: BAE43251.1.
AK053044 mRNA. Translation: BAC35248.1.
AK163135 mRNA. Translation: BAE37208.1.
BC027800 mRNA. Translation: AAH27800.1. Different initiation.
BC076578 mRNA. Translation: AAH76578.1.
AB055408 mRNA. Translation: BAC53806.1.
CCDSiCCDS37637.1.
RefSeqiNP_780377.1. NM_175168.4.
UniGeneiMm.181833.

Genome annotation databases

EnsembliENSMUST00000044442; ENSMUSP00000043703; ENSMUSG00000023972.
GeneIDi71461.
KEGGimmu:71461.
UCSCiuc008cth.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF531873 mRNA. Translation: AAQ10071.1 .
AY303976 Genomic DNA. Translation: AAQ73496.1 .
AK018379 mRNA. Translation: BAE43251.1 .
AK053044 mRNA. Translation: BAC35248.1 .
AK163135 mRNA. Translation: BAE37208.1 .
BC027800 mRNA. Translation: AAH27800.1 . Different initiation.
BC076578 mRNA. Translation: AAH76578.1 .
AB055408 mRNA. Translation: BAC53806.1 .
CCDSi CCDS37637.1.
RefSeqi NP_780377.1. NM_175168.4.
UniGenei Mm.181833.

3D structure databases

ProteinModelPortali Q8BKG3.
SMRi Q8BKG3. Positions 26-685, 794-1046.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q8BKG3. 1 interaction.
MINTi MINT-4111157.
STRINGi 10090.ENSMUSP00000043703.

PTM databases

PhosphoSitei Q8BKG3.

Proteomic databases

MaxQBi Q8BKG3.
PaxDbi Q8BKG3.
PRIDEi Q8BKG3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000044442 ; ENSMUSP00000043703 ; ENSMUSG00000023972 .
GeneIDi 71461.
KEGGi mmu:71461.
UCSCi uc008cth.2. mouse.

Organism-specific databases

CTDi 5754.
MGIi MGI:1918711. Ptk7.

Phylogenomic databases

eggNOGi COG0515.
GeneTreei ENSGT00760000118818.
HOGENOMi HOG000115767.
HOVERGENi HBG008320.
InParanoidi Q8BKG3.
KOi K05127.
OMAi DGTWYRC.
OrthoDBi EOG790G1M.
PhylomeDBi Q8BKG3.
TreeFami TF326835.

Miscellaneous databases

NextBioi 333833.
PROi Q8BKG3.
SOURCEi Search...

Gene expression databases

Bgeei Q8BKG3.
CleanExi MM_PTK7.
ExpressionAtlasi Q8BKG3. baseline.
Genevestigatori Q8BKG3.

Family and domain databases

Gene3Di 2.60.40.10. 7 hits.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
IPR020635. Tyr_kinase_cat_dom.
[Graphical view ]
Pfami PF07679. I-set. 5 hits.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view ]
PRINTSi PR00109. TYRKINASE.
SMARTi SM00409. IG. 1 hit.
SM00408. IGc2. 6 hits.
SM00219. TyrKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS50835. IG_LIKE. 7 hits.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and characterization of the full-length mouse Ptk7 cDNA encoding a defective receptor protein tyrosine kinase."
    Jung J.-W., Shin W.S., Song J., Lee S.-T.
    Gene 328:75-84(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], TISSUE SPECIFICITY.
    Strain: BALB/c and C57BL/6.
    Tissue: Liver.
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Head and Lung.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6 and FVB/N.
    Tissue: Brain and Mammary tumor.
  4. "Isolation and characterization of novel human and mouse genes, which are expressed in the digestive tract."
    Daigo Y., Takayama I., Fujino M.A.
    Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 774-1062.
    Strain: W/Wv.
  5. "PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates."
    Lu X., Borchers A.G.M., Jolicoeur C., Rayburn H., Baker J.C., Tessier-Lavigne M.
    Nature 430:93-98(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, DISRUPTION PHENOTYPE.
  6. "The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation."
    Gundry R.L., Raginski K., Tarasova Y., Tchernyshyov I., Bausch-Fluck D., Elliott S.T., Boheler K.R., Van Eyk J.E., Wollscheid B.
    Mol. Cell. Proteomics 8:2555-2569(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-108 AND ASN-397.
    Tissue: Myoblast.
  7. "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
    Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D.
    Nat. Biotechnol. 27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-98; ASN-275; ASN-397 AND ASN-559.
  8. "PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation."
    Yen W.W., Williams M., Periasamy A., Conaway M., Burdsal C., Keller R., Lu X., Sutherland A.
    Development 136:2039-2048(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, DISRUPTION PHENOTYPE.
  9. "The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear."
    Paudyal A., Damrau C., Patterson V.L., Ermakov A., Formstone C., Lalanne Z., Wells S., Lu X., Norris D.P., Dean C.H., Henderson D.J., Murdoch J.N.
    BMC Dev. Biol. 10:87-87(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, DISRUPTION PHENOTYPE.

Entry informationi

Entry nameiPTK7_MOUSE
AccessioniPrimary (citable) accession number: Q8BKG3
Secondary accession number(s): Q3V422
, Q6W8S9, Q8CHK5, Q8K178
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: March 1, 2003
Last modified: November 26, 2014
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Human and mouse protein kinases
    Human and mouse protein kinases: classification and index
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3