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Protein

Transporter

Gene

Slc6a11

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Biological processSymportUniRule annotationSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
TransporterUniRule annotation
Gene namesi
Name:Slc6a11Imported
Synonyms:Gabt4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:95630. Slc6a11.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei40 – 60HelicalSequence analysisAdd BLAST21
Transmembranei97 – 113HelicalSequence analysisAdd BLAST17
Transmembranei209 – 232HelicalSequence analysisAdd BLAST24
Transmembranei252 – 277HelicalSequence analysisAdd BLAST26
Transmembranei289 – 315HelicalSequence analysisAdd BLAST27
Transmembranei392 – 417HelicalSequence analysisAdd BLAST26
Transmembranei423 – 447HelicalSequence analysisAdd BLAST25
Transmembranei468 – 487HelicalSequence analysisAdd BLAST20
Transmembranei507 – 528HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ8BKG0.
PeptideAtlasiQ8BKG0.

Structurei

3D structure databases

ProteinModelPortaliQ8BKG0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3659. Eukaryota.
COG0733. LUCA.
HOVERGENiHBG071421.

Family and domain databases

CDDicd11508. SLC6sbd_GAT3. 1 hit.
InterProiView protein in InterPro
IPR000175. Na/ntran_symport.
IPR002982. Na/ntran_symport_GABA_GAT3.
PANTHERiPTHR11616. PTHR11616. 1 hit.
PfamiView protein in Pfam
PF00209. SNF. 1 hit.
PRINTSiPR01197. GAT3TRNSPORT.
PR00176. NANEUSMPORT.
PROSITEiView protein in PROSITE
PS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
PS00754. NA_NEUROTRAN_SYMP_2. 1 hit.
PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q8BKG0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VHERGHWNNK VEFVLSVAGE IIGLGNVWRF PYLCYKNGGG AFLIPYVVFF
60 70 80 90 100
ICCGIPVFFL ETALGQFTSE GGITCWRRVC PLFEGIGYAT QVIEAHLNVY
110 120 130 140 150
YIIILAWAIF YLSNCFTTEL PWATCGHEWN TEKCVEFQKL NFSNYSHVSL
160 170 180 190 200
QNATSPVMEF WERRVLAISD GIEHIGNLRW ELALCLLAAW TICYFCIWKG
210 220 230 240 250
TKSTGKVVYV TATFPYIMLL ILLIRGVTLP GASEGIKFYL YPDLSRLSDP
260 270 280 290 300
QVWVDAGTQI FFSYAICLGC LTALGSYNNY NNNCYRDCIM LCCLNSGTSF
310 320 330 340 350
VAGFAIFSVL GFMAYEQGVP IAEVAESGPG LAFIAYPKAV TMMPLSPLWA
360 370 380 390 400
TLFFMMLIFL GLDSQFVCVE SLVTAVVDMY PKVFRRGYRR ELLILALSII
410 420 430 440 450
SYFLGLVMLT EGGMYIFQLF DSYAASGMCL LFVAIFECVC IGWVYGSNRF
460 470 480 490 500
YDNIEDMIGY RPLSLIKWCW KVVTPGICAG IFIFFLVKYK PLKYNNVYTY
510 520 530 540 550
PAWGYGIGWL MALSSMLCIP LWIFIKLWKT EGTLPEKLQK LTVPSADLKM
560 570 580
RGKLGASPRT VTVNDCEAKV KGDGTISAIT EKETHF
Length:586
Mass (Da):66,065
Last modified:March 1, 2003 - v1
Checksum:i78EB41F1A9EB1A38
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK053261 mRNA. Translation: BAC35326.1.
UniGeneiMm.44683.
Mm.448312.

Similar proteinsi

Entry informationi

Entry nameiQ8BKG0_MOUSE
AccessioniPrimary (citable) accession number: Q8BKG0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 27, 2017
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)