Reviewed,
UniProtKB/Swiss-Prot Q8BK84 (DUPD1_MOUSE)
Last modified
June 16, 2009.
Version 46.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Dual specificity phosphatase DUPD1 EC=3.1.3.48 EC=3.1.3.16 | ||
| Gene names |
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| Organism | Mus musculus (Mouse) | ||
| Taxonomic identifier | 10090 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus |
Protein attributes
| Sequence length | 215 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Catalytic activity | Protein tyrosine phosphate + H2O = protein tyrosine + phosphate. A phosphoprotein + H2O = a protein + phosphate. |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. Contains 1 tyrosine-protein phosphatase domain. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Molecular function | Hydrolase Protein phosphatase |
| Gene Ontology (GO) | |
| Biological process | protein amino acid dephosphorylation Inferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | protein tyrosine phosphatase activity Inferred from electronic annotation. Source: EC protein tyrosine/serine/threonine phosphatase activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. Hayashizaki Y.Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6J. |
| [2] | "Genomic sequence analysis in the mouse T-complex region." Brathwaite M., Waeltz P., Nagaraja R. Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J. |
Cross-references
Sequence databases | |
|---|---|
| AK075665 mRNA. Translation: BAC35883.1. AY294423 Genomic DNA. Translation: AAQ01518.1. | |
| IPI | IPI00222524. |
| RefSeq | NP_001013848.1. |
| UniGene | Mm.295860 |
3D structure databases | |
| HSSP | HSSP built from PDB template 1VHR based on UniProtKB P51452. |
| ModBase | Search... |
Genome annotation databases | |
| Ensembl | ENSMUSG00000063821. Mus musculus. [Contig view] |
| GeneID | 435391. |
| KEGG | mmu:435391. |
Organism-specific databases | |
| MGI | MGI:3647127. Dupd1. |
Phylogenomic databases | |
| HOGENOM | Q8BK84. |
| HOVERGEN | Q8BK84. |
| OMA | Q8BK84. HSKILVH. |
Enzyme and pathway databases | |
| BRENDA | 3.1.3.16. 244. 3.1.3.48. 244. |
Gene expression databases | |
| ArrayExpress | Q8BK84. |
| Bgee | Q8BK84. |
Family and domain databases | |
| InterPro | IPR000387. Tyr_Pase. IPR016130. Tyr_Pase_AS. IPR000340. Tyr_Pase_dual_specific. [Graphical view] |
| Pfam | PF00782. DSPc. 1 hit. [Graphical view] |
| SMART | SM00195. DSPc. 1 hit. [Graphical view] |
| PROSITE | PS00383. TYR_PHOSPHATASE_1. 1 hit. PS50056. TYR_PHOSPHATASE_2. 1 hit. PS50054. TYR_PHOSPHATASE_DUAL. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 410078. |
| SOURCE | Search... |
Entry information
| Entry name | DUPD1_MOUSE | ||||||||
| Accession | Primary (citable) accession number: Q8BK84 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HPI (Human Proteome Initiative) | ||||||||
Relevant documents
| MGD cross-references Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot |
| SIMILARITY comments Index of protein domains and families |

Clusters with


