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Q8BK72 (RT27_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
28S ribosomal protein S27, mitochondrial
Short name=MRP-S27
Short name=S27mt
Gene names
Name:Mrps27
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length415 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subunit structure

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins. Interacts with NOA1 By similarity. UniProtKB Q92552

Subcellular location

Mitochondrion By similarity UniProtKB Q92552.

Sequence similarities

Contains 2 PPR (pentatricopeptide) repeats.

Ontologies

Keywords
   Cellular componentMitochondrion
   DomainCoiled coil
Repeat
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentmitochondrion

Inferred from direct assay PubMed 18614015. Source: MGI

ribosome

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 41541528S ribosomal protein S27, mitochondrial
PRO_0000261586

Regions

Repeat105 – 13935PPR 1
Repeat140 – 17536PPR 2
Coiled coil369 – 41547 Potential

Experimental info

Sequence conflict811S → C in BAC36116. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q8BK72 [UniParc].

Last modified July 27, 2011. Version 2.
Checksum: 188A19628C12CA26

FASTA41547,779
        10         20         30         40         50         60 
MAAPMVRCGM LLARRLDASR LCLAGKRCLL SAAYVDSHQW EAREKEEYHL ADLASLMDKA 

        70         80         90        100        110        120 
YERKLPVSSL SISRFVDNIA SREDLDSAEY YLYKFRHSPN CWYLRDWTIH SWIRQCLKYG 

       130        140        150        160        170        180 
AQDKALYTLV NKVQYGIFPD NFTFNLLMDY FIKKGNYKDA LSVVFEIMMQ EAFDVPSTQF 

       190        200        210        220        230        240 
LSLYVLYRCL AEKTELTWEE ERDFGASLLL SGLKQRNTVG LSSQLYGYAL LGKVELQRGV 

       250        260        270        280        290        300 
RAVYHGMPLM WTPGYLDRAL QVMERVASSP EDLKLGREVL DVLDGVLKVV TSPDVQTSEA 

       310        320        330        340        350        360 
QPQEGEDGLG SANLVEQLDT EEPEQSKLPR YLERFQASRS KLQELNRVES ESLLTLTTQL 

       370        380        390        400        410 
VKEKLPACEA EDLATYEQKL REWHLERVQL IQREQEQREK AKQEYQALSA AEKAA

« Hide

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Embryo.
[2]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AK076008 mRNA. Translation: BAC36116.1.
AC132347 Genomic DNA. No translation available.
IPIIPI00222514.
RefSeqNP_776118.2. NM_173757.3.
UniGeneMm.30208.

3D structure databases

ProteinModelPortalQ8BK72.
ModBaseSearch...

PTM databases

PhosphoSiteQ8BK72.

Proteomic databases

PaxDbQ8BK72.
PRIDEQ8BK72.

Protocols and materials databases

DNASU218506.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000052249; ENSMUSP00000062326; ENSMUSG00000041632.
GeneID218506.
KEGGmmu:218506.
UCSCuc007rpn.1. mouse.

Organism-specific databases

CTD23107.
MGIMGI:1919064. Mrps27.

Phylogenomic databases

eggNOGNOG313611.
GeneTreeENSGT00390000007246.
HOGENOMHOG000070071.
HOVERGENHBG006970.
InParanoidQ8BK72.
OMAYLRDWTI.
OrthoDBEOG40CHHH.

Gene expression databases

ArrayExpressQ8BK72.
BgeeQ8BK72.
CleanExMM_MRPS27.
GenevestigatorQ8BK72.
GermOnlineENSMUSG00000041632. Mus musculus.

Family and domain databases

InterProIPR002885. Pentatricopeptide_repeat.
IPR019266. Ribosomal_S27_mit.
[Graphical view]
PfamPF10037. MRP-S27. 1 hit.
[Graphical view]
PROSITEPS51375. PPR. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio376327.
SOURCESearch...

Entry information

Entry nameRT27_MOUSE
AccessionPrimary (citable) accession number: Q8BK72
Secondary accession number(s): E9QKZ5
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: July 27, 2011
Last modified: May 1, 2013
This is version 69 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

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