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Protein

alpha-1,2-Mannosidase

Gene

Edem2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotation, Hydrolase

Enzyme and pathway databases

ReactomeiR-MMU-901032 ER Quality Control Compartment (ERQC)

Protein family/group databases

CAZyiGH47 Glycoside Hydrolase Family 47

Names & Taxonomyi

Protein namesi
Recommended name:
alpha-1,2-MannosidaseUniRule annotation (EC:3.2.1.-UniRule annotation)
Gene namesi
Name:Edem2Imported
ORF Names:mCG_21080Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1915540 Edem2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501410727322 – 577alpha-1,2-MannosidaseSequence analysisAdd BLAST556

Proteomic databases

MaxQBiQ8BJT9

Expressioni

Gene expression databases

BgeeiENSMUSG00000038312

Interactioni

Protein-protein interaction databases

IntActiQ8BJT9, 8 interactors
STRINGi10090.ENSMUSP00000041202

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 47 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2429 Eukaryota
ENOG410XS6F LUCA
GeneTreeiENSGT00530000063069
HOVERGENiHBG051158
KOiK10085
OMAiESFYYAY
OrthoDBiEOG091G04YS
TreeFamiTF300807

Family and domain databases

Gene3Di1.50.10.10, 1 hit
InterProiView protein in InterPro
IPR012341 6hp_glycosidase-like_sf
IPR001382 Glyco_hydro_47
IPR036026 Seven-hairpin_glycosidases
PfamiView protein in Pfam
PF01532 Glyco_hydro_47, 1 hit
PRINTSiPR00747 GLYHDRLASE47
SUPFAMiSSF48225 SSF48225, 1 hit

Sequencei

Sequence statusi: Complete.

Q8BJT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPFRLLIPLG LVCVLLPLHH GAPGPDGTAP DPAHYRERVK AMFYHAYDSY
60 70 80 90 100
LENAFPYDEL RPLTCDGHDT WGSFSLTLID ALDTLLILGN TSEFQRVVEV
110 120 130 140 150
LQDNVDFDID VNASVFETNI RVVGGLLSAH LLSKKAGVEV EAGWPCSGPL
160 170 180 190 200
LRMAEEAARK LLPAFQTPTG MPYGTVNLLH GVNPGETPVT CTAGIGTFIV
210 220 230 240 250
EFATLSSLTG DPVFEDVARV ALMRLWESRS DIGLVGNHID VLTGKWVAQD
260 270 280 290 300
AGIGAGVDSY FEYLVKGAIL LQDKKLMAMF LEYNKAIRNY THFDDWYLWV
310 320 330 340 350
QMYKGTVSMP VFQSLEAYWP GLQSLIGDID NAMRTFLNYY TVWKQFGGLP
360 370 380 390 400
EFYNIPQGYT VEKREGYPLR PELIESAMYL YRATGDPTLL ELGRDAVESI
410 420 430 440 450
EKISKVECGF ATIKDLRDHK LDNRMESFFL AETVKYLYLL FHPNNFIHNN
460 470 480 490 500
GSTFDSVMTP HGECILGAGG YIFNTEAHPI DPAALHCCRR LKEEQWEVED
510 520 530 540 550
LIKEFYSLKQ SRPKRAQRKT VRSGPWEPQS GPATLSSPAN QPREKQPAQQ
560 570
RTPLLSCPSQ PFTSKLALLG QVFLDSS
Length:577
Mass (Da):64,610
Last modified:March 1, 2003 - v1
Checksum:i3B6992FE87F17ED9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL929233 Genomic DNA No translation available.
AK079296 mRNA Translation: BAC37599.1
AK155024 mRNA Translation: BAE32997.1
AK166998 mRNA Translation: BAE39177.1
CH466551 Genomic DNA Translation: EDL06140.1
RefSeqiNP_663512.2, NM_145537.2
UniGeneiMm.273706

Genome annotation databases

EnsembliENSMUST00000040833; ENSMUSP00000041202; ENSMUSG00000038312
GeneIDi108687
KEGGimmu:108687
UCSCiuc008nlg.2 mouse

Similar proteinsi

Entry informationi

Entry nameiQ8BJT9_MOUSE
AccessioniPrimary (citable) accession number: Q8BJT9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: April 25, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health