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Protein

alpha-1,2-Mannosidase

Gene

Edem2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Enzyme and pathway databases

ReactomeiR-MMU-901032. ER Quality Control Compartment (ERQC).

Protein family/group databases

CAZyiGH47. Glycoside Hydrolase Family 47.

Names & Taxonomyi

Protein namesi
Recommended name:
alpha-1,2-MannosidaseUniRule annotation (EC:3.2.1.-UniRule annotation)
Gene namesi
Name:Edem2Imported
ORF Names:mCG_21080Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1915540. Edem2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence analysisAdd
BLAST
Chaini22 – 577556alpha-1,2-MannosidaseSequence analysisPRO_5007927338Add
BLAST

Expressioni

Gene expression databases

BgeeiENSMUSG00000038312.

Interactioni

GO - Molecular functioni

  • glycoprotein binding Source: ParkinsonsUK-UCL

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041202.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 47 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2429. Eukaryota.
ENOG410XS6F. LUCA.
GeneTreeiENSGT00530000063069.
HOVERGENiHBG051158.
KOiK10085.
OMAiKELMSMF.
OrthoDBiEOG091G04YS.
TreeFamiTF300807.

Family and domain databases

Gene3Di1.50.10.50. 1 hit.
InterProiIPR001382. Glyco_hydro_47.
[Graphical view]
PfamiPF01532. Glyco_hydro_47. 1 hit.
[Graphical view]
PRINTSiPR00747. GLYHDRLASE47.
SUPFAMiSSF48225. SSF48225. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8BJT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPFRLLIPLG LVCVLLPLHH GAPGPDGTAP DPAHYRERVK AMFYHAYDSY
60 70 80 90 100
LENAFPYDEL RPLTCDGHDT WGSFSLTLID ALDTLLILGN TSEFQRVVEV
110 120 130 140 150
LQDNVDFDID VNASVFETNI RVVGGLLSAH LLSKKAGVEV EAGWPCSGPL
160 170 180 190 200
LRMAEEAARK LLPAFQTPTG MPYGTVNLLH GVNPGETPVT CTAGIGTFIV
210 220 230 240 250
EFATLSSLTG DPVFEDVARV ALMRLWESRS DIGLVGNHID VLTGKWVAQD
260 270 280 290 300
AGIGAGVDSY FEYLVKGAIL LQDKKLMAMF LEYNKAIRNY THFDDWYLWV
310 320 330 340 350
QMYKGTVSMP VFQSLEAYWP GLQSLIGDID NAMRTFLNYY TVWKQFGGLP
360 370 380 390 400
EFYNIPQGYT VEKREGYPLR PELIESAMYL YRATGDPTLL ELGRDAVESI
410 420 430 440 450
EKISKVECGF ATIKDLRDHK LDNRMESFFL AETVKYLYLL FHPNNFIHNN
460 470 480 490 500
GSTFDSVMTP HGECILGAGG YIFNTEAHPI DPAALHCCRR LKEEQWEVED
510 520 530 540 550
LIKEFYSLKQ SRPKRAQRKT VRSGPWEPQS GPATLSSPAN QPREKQPAQQ
560 570
RTPLLSCPSQ PFTSKLALLG QVFLDSS
Length:577
Mass (Da):64,610
Last modified:March 1, 2003 - v1
Checksum:i3B6992FE87F17ED9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL929233 Genomic DNA. No translation available.
AK079296 mRNA. Translation: BAC37599.1.
AK155024 mRNA. Translation: BAE32997.1.
AK166998 mRNA. Translation: BAE39177.1.
CH466551 Genomic DNA. Translation: EDL06140.1.
RefSeqiNP_663512.2. NM_145537.2.
UniGeneiMm.273706.

Genome annotation databases

EnsembliENSMUST00000040833; ENSMUSP00000041202; ENSMUSG00000038312.
GeneIDi108687.
KEGGimmu:108687.
UCSCiuc008nlg.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL929233 Genomic DNA. No translation available.
AK079296 mRNA. Translation: BAC37599.1.
AK155024 mRNA. Translation: BAE32997.1.
AK166998 mRNA. Translation: BAE39177.1.
CH466551 Genomic DNA. Translation: EDL06140.1.
RefSeqiNP_663512.2. NM_145537.2.
UniGeneiMm.273706.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041202.

Protein family/group databases

CAZyiGH47. Glycoside Hydrolase Family 47.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000040833; ENSMUSP00000041202; ENSMUSG00000038312.
GeneIDi108687.
KEGGimmu:108687.
UCSCiuc008nlg.2. mouse.

Organism-specific databases

CTDi55741.
MGIiMGI:1915540. Edem2.

Phylogenomic databases

eggNOGiKOG2429. Eukaryota.
ENOG410XS6F. LUCA.
GeneTreeiENSGT00530000063069.
HOVERGENiHBG051158.
KOiK10085.
OMAiKELMSMF.
OrthoDBiEOG091G04YS.
TreeFamiTF300807.

Enzyme and pathway databases

ReactomeiR-MMU-901032. ER Quality Control Compartment (ERQC).

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000038312.

Family and domain databases

Gene3Di1.50.10.50. 1 hit.
InterProiIPR001382. Glyco_hydro_47.
[Graphical view]
PfamiPF01532. Glyco_hydro_47. 1 hit.
[Graphical view]
PRINTSiPR00747. GLYHDRLASE47.
SUPFAMiSSF48225. SSF48225. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ8BJT9_MOUSE
AccessioniPrimary (citable) accession number: Q8BJT9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 7, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.