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Protein

Zinc finger protein 879

Gene

Znf879

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri204 – 226C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri232 – 254C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri260 – 282C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri288 – 310C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri316 – 338C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri344 – 366C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri372 – 394C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri400 – 422C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri428 – 450C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri456 – 478C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri484 – 506C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri512 – 534C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri540 – 562C2H2-type 13PROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 879
Gene namesi
Name:Znf879
Synonyms:Zfp879
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:3053099. Zfp879.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003939681 – 563Zinc finger protein 879Add BLAST563

Proteomic databases

MaxQBiQ8BI99.
PaxDbiQ8BI99.
PRIDEiQ8BI99.

PTM databases

iPTMnetiQ8BI99.
PhosphoSitePlusiQ8BI99.

Expressioni

Gene expression databases

BgeeiENSMUSG00000044296.
ExpressionAtlasiQ8BI99. baseline and differential.
GenevisibleiQ8BI99. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000061782.

Structurei

3D structure databases

ProteinModelPortaliQ8BI99.
SMRiQ8BI99.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 85KRABPROSITE-ProRule annotationAdd BLAST72

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri204 – 226C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri232 – 254C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri260 – 282C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri288 – 310C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri316 – 338C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri344 – 366C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri372 – 394C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri400 – 422C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri428 – 450C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri456 – 478C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri484 – 506C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri512 – 534C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri540 – 562C2H2-type 13PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00900000140896.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiQ8BI99.
KOiK09228.
OMAiHSALIIH.
OrthoDBiEOG091G02KC.
PhylomeDBiQ8BI99.
TreeFamiTF350823.

Family and domain databases

CDDicd07765. KRAB_A-box. 1 hit.
Gene3Di3.30.40.10. 1 hit.
InterProiView protein in InterPro
IPR001909. KRAB.
IPR036051. KRAB_dom_sf.
IPR036236. Znf_C2H2_sf.
IPR013087. Znf_C2H2_type.
IPR013083. Znf_RING/FYVE/PHD.
PfamiView protein in Pfam
PF01352. KRAB. 1 hit.
SMARTiView protein in SMART
SM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 13 hits.
SUPFAMiSSF109640. SSF109640. 1 hit.
SSF57667. SSF57667. 7 hits.
PROSITEiView protein in PROSITE
PS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 13 hits.
PS50157. ZINC_FINGER_C2H2_2. 13 hits.

Sequencei

Sequence statusi: Complete.

Q8BI99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTRLLPAQV QEPVTFRDVA VSFSQDEWLH LDPAQRTLYR EVMLENYSNL
60 70 80 90 100
VSLGILFSKP KVIAQLEQAE DFPMVESGMF QGVYLGWKSL FEPIVSKEEN
110 120 130 140 150
KKVLKNQRVD KFFNFILGKT CVNEEQLEEQ PGNKKNPFSE MLLSVRRGCR
160 170 180 190 200
QERGFPGVGL VRNPGIKLPF RRKPGVAAGG GKPHLQQYSV LFKQLGFNRA
210 220 230 240 250
RQLCKCNICG KVFFHSSSLS KHQRTHTGEK LYKCQGCRKA FSQRSSLAQH
260 270 280 290 300
LRVHTGEKPY LCSDCGKAFS FTTSLIGHQR MHTGERPYEC KECGKTFKGS
310 320 330 340 350
SSLHNHQRIH TGEKPYKCNE CGRAFSQCSS LIQHHRIHTG EKPYECSQCG
360 370 380 390 400
KAFTSISRLS RHHRVHTGEK PFHCNVCGKV FSYHSALTIH QRTHTGEKPY
410 420 430 440 450
ACKECGKAFS QSSALTQHQR IHTGEKPYKC AECGKAFSWL SRLNIHHRIH
460 470 480 490 500
TGEKPYHCKE CGKAFSSHSA VNTHRKIHTG EKPYKCSDCE KAFNQSSALI
510 520 530 540 550
QHQRIHTGEK PFNCKVCGKA FRQSSSLMTH MRIHTGERPY RCEACGKAFS
560
QSSSLANHQK THY
Length:563
Mass (Da):64,066
Last modified:March 1, 2003 - v1
Checksum:i8CA7DDD69D88E889
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK036152 mRNA. Translation: BAC29322.1.
AL627215 Genomic DNA. Translation: CAI35294.1.
CH466575 Genomic DNA. Translation: EDL33691.1.
CCDSiCCDS24638.1.
RefSeqiNP_001277708.1. NM_001290779.1.
NP_775563.1. NM_173387.3.
UniGeneiMm.191846.

Genome annotation databases

EnsembliENSMUST00000049625; ENSMUSP00000061782; ENSMUSG00000044296.
ENSMUST00000109134; ENSMUSP00000104762; ENSMUSG00000044296.
GeneIDi214779.
KEGGimmu:214779.
UCSCiuc007isr.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiZN879_MOUSE
AccessioniPrimary (citable) accession number: Q8BI99
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: March 1, 2003
Last modified: October 25, 2017
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families