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Q8BHS6

- ARMX3_MOUSE

UniProt

Q8BHS6 - ARMX3_MOUSE

Protein

Armadillo repeat-containing X-linked protein 3

Gene

Armcx3

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein binding Source: MGI

    GO - Biological processi

    1. cellular protein localization Source: MGI
    2. positive regulation of transcription from RNA polymerase II promoter Source: MGI

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Armadillo repeat-containing X-linked protein 3
    Gene namesi
    Name:Armcx3
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome X

    Organism-specific databases

    MGIiMGI:1918953. Armcx3.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of mitochondrial outer membrane Source: MGI

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 379379Armadillo repeat-containing X-linked protein 3PRO_0000191368Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei61 – 611Phosphoserine1 Publication
    Modified residuei67 – 671PhosphoserineBy similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PaxDbiQ8BHS6.
    PRIDEiQ8BHS6.

    PTM databases

    PhosphoSiteiQ8BHS6.

    Expressioni

    Gene expression databases

    BgeeiQ8BHS6.
    CleanExiMM_ARMCX3.
    GenevestigatoriQ8BHS6.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8BHS6.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei7 – 2923HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati111 – 15141ARM 1Add
    BLAST
    Repeati153 – 19240ARM 2Add
    BLAST
    Repeati233 – 27240ARM 3Add
    BLAST

    Sequence similaritiesi

    Contains 3 ARM repeats.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG303147.
    GeneTreeiENSGT00550000074488.
    HOGENOMiHOG000231611.
    HOVERGENiHBG080349.
    InParanoidiA2AKS4.
    OMAiCPGARYN.
    OrthoDBiEOG70PBZ0.
    PhylomeDBiQ8BHS6.
    TreeFamiTF335652.

    Family and domain databases

    Gene3Di1.25.10.10. 2 hits.
    InterProiIPR011989. ARM-like.
    IPR006911. ARM-rpt_dom.
    IPR016024. ARM-type_fold.
    IPR000225. Armadillo.
    [Graphical view]
    PfamiPF04826. Arm_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF48371. SSF48371. 1 hit.
    PROSITEiPS50176. ARM_REPEAT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8BHS6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGYARKVGWV TAGLVIGAGA CYCIYRLTRG RKQNKEKMAE GGSGDVDDAG    50
    DCSGARYNDW SDDDDDSNES KSIVWYPPWA RIGTEAGTRA RARARARATR 100
    ARRAVQKRAS PNSDDTVLSP QELQKVLCLV EMSEKPYILE AALIALGNNA 150
    AYAFNRDIIR DLGGLPIVAK ILNTRDPIVK EKALIVLNNL SVNAENQRRL 200
    KVYMNQVCDD TVTSRLNSSV QLAGLRLLTN MTVTNEYQHI LANSISDFFR 250
    LFSAGNEETK LQVLKLLLNL AENPAMTREL LRAQVPSSLG SLFNKKEYKE 300
    VILKLLIIFE NINDNFKWEE NEPAQNHFSE GSLFFFLKEF QVCADKVLGI 350
    ESRHDFQVRV KVGKFVAKLT ERMFPKSQE 379
    Length:379
    Mass (Da):42,620
    Last modified:March 1, 2003 - v1
    Checksum:i6EA7B87544652055
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti4 – 41A → T in AAH11101. (PubMed:15489334)Curated
    Sequence conflicti53 – 531S → P in BAB23399. (PubMed:16141072)Curated
    Sequence conflicti68 – 681N → Y in BAB23399. (PubMed:16141072)Curated
    Sequence conflicti333 – 3331L → P in BAB23399. (PubMed:16141072)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK004598 mRNA. Translation: BAB23399.1.
    AK030729 mRNA. Translation: BAC27102.1.
    AL772348 Genomic DNA. Translation: CAM20585.1.
    BC011101 mRNA. Translation: AAH11101.1.
    BC051113 mRNA. Translation: AAH51113.1.
    CCDSiCCDS30400.1.
    RefSeqiNP_082146.2. NM_027870.3.
    XP_006528672.1. XM_006528609.1.
    UniGeneiMm.67949.

    Genome annotation databases

    EnsembliENSMUST00000081834; ENSMUSP00000080518; ENSMUSG00000049047.
    ENSMUST00000086880; ENSMUSP00000084093; ENSMUSG00000049047.
    ENSMUST00000086884; ENSMUSP00000084097; ENSMUSG00000049047.
    GeneIDi71703.
    KEGGimmu:71703.
    UCSCiuc009ugo.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK004598 mRNA. Translation: BAB23399.1 .
    AK030729 mRNA. Translation: BAC27102.1 .
    AL772348 Genomic DNA. Translation: CAM20585.1 .
    BC011101 mRNA. Translation: AAH11101.1 .
    BC051113 mRNA. Translation: AAH51113.1 .
    CCDSi CCDS30400.1.
    RefSeqi NP_082146.2. NM_027870.3.
    XP_006528672.1. XM_006528609.1.
    UniGenei Mm.67949.

    3D structure databases

    ProteinModelPortali Q8BHS6.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q8BHS6.

    Proteomic databases

    PaxDbi Q8BHS6.
    PRIDEi Q8BHS6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000081834 ; ENSMUSP00000080518 ; ENSMUSG00000049047 .
    ENSMUST00000086880 ; ENSMUSP00000084093 ; ENSMUSG00000049047 .
    ENSMUST00000086884 ; ENSMUSP00000084097 ; ENSMUSG00000049047 .
    GeneIDi 71703.
    KEGGi mmu:71703.
    UCSCi uc009ugo.2. mouse.

    Organism-specific databases

    CTDi 51566.
    MGIi MGI:1918953. Armcx3.

    Phylogenomic databases

    eggNOGi NOG303147.
    GeneTreei ENSGT00550000074488.
    HOGENOMi HOG000231611.
    HOVERGENi HBG080349.
    InParanoidi A2AKS4.
    OMAi CPGARYN.
    OrthoDBi EOG70PBZ0.
    PhylomeDBi Q8BHS6.
    TreeFami TF335652.

    Miscellaneous databases

    NextBioi 334271.
    PROi Q8BHS6.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q8BHS6.
    CleanExi MM_ARMCX3.
    Genevestigatori Q8BHS6.

    Family and domain databases

    Gene3Di 1.25.10.10. 2 hits.
    InterProi IPR011989. ARM-like.
    IPR006911. ARM-rpt_dom.
    IPR016024. ARM-type_fold.
    IPR000225. Armadillo.
    [Graphical view ]
    Pfami PF04826. Arm_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48371. SSF48371. 1 hit.
    PROSITEi PS50176. ARM_REPEAT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6J.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/N.
      Tissue: Mammary tumor.
    4. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-61, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Liver.

    Entry informationi

    Entry nameiARMX3_MOUSE
    AccessioniPrimary (citable) accession number: Q8BHS6
    Secondary accession number(s): A2AKS4, Q91VP8, Q9DC32
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 20, 2005
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 92 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3