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Protein

Armadillo repeat-containing X-linked protein 3

Gene

Armcx3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • cellular protein localization Source: MGI
  • positive regulation of transcription from RNA polymerase II promoter Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Armadillo repeat-containing X-linked protein 3
Gene namesi
Name:Armcx3
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:1918953. Armcx3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 29HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

  • integral component of mitochondrial outer membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001913681 – 379Armadillo repeat-containing X-linked protein 3Add BLAST379

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei61PhosphoserineCombined sources1
Modified residuei67PhosphoserineCombined sources1
Modified residuei72PhosphoserineBy similarity1
Modified residuei110PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ8BHS6.
MaxQBiQ8BHS6.
PaxDbiQ8BHS6.
PeptideAtlasiQ8BHS6.
PRIDEiQ8BHS6.

PTM databases

iPTMnetiQ8BHS6.
PhosphoSitePlusiQ8BHS6.

Expressioni

Gene expression databases

BgeeiENSMUSG00000049047.
CleanExiMM_ARMCX3.
GenevisibleiQ8BHS6. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000080518.

Structurei

3D structure databases

ProteinModelPortaliQ8BHS6.
SMRiQ8BHS6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati111 – 151ARM 1Add BLAST41
Repeati153 – 192ARM 2Add BLAST40
Repeati233 – 272ARM 3Add BLAST40

Sequence similaritiesi

Contains 3 ARM repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IVCU. Eukaryota.
ENOG4112958. LUCA.
GeneTreeiENSGT00550000074488.
HOGENOMiHOG000231611.
HOVERGENiHBG080349.
InParanoidiQ8BHS6.
OMAiCPGARYN.
OrthoDBiEOG091G0PCU.
PhylomeDBiQ8BHS6.
TreeFamiTF335652.

Family and domain databases

Gene3Di1.25.10.10. 2 hits.
InterProiIPR011989. ARM-like.
IPR006911. ARM-rpt_dom.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
[Graphical view]
PfamiPF04826. Arm_2. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50176. ARM_REPEAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BHS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGYARKVGWV TAGLVIGAGA CYCIYRLTRG RKQNKEKMAE GGSGDVDDAG
60 70 80 90 100
DCSGARYNDW SDDDDDSNES KSIVWYPPWA RIGTEAGTRA RARARARATR
110 120 130 140 150
ARRAVQKRAS PNSDDTVLSP QELQKVLCLV EMSEKPYILE AALIALGNNA
160 170 180 190 200
AYAFNRDIIR DLGGLPIVAK ILNTRDPIVK EKALIVLNNL SVNAENQRRL
210 220 230 240 250
KVYMNQVCDD TVTSRLNSSV QLAGLRLLTN MTVTNEYQHI LANSISDFFR
260 270 280 290 300
LFSAGNEETK LQVLKLLLNL AENPAMTREL LRAQVPSSLG SLFNKKEYKE
310 320 330 340 350
VILKLLIIFE NINDNFKWEE NEPAQNHFSE GSLFFFLKEF QVCADKVLGI
360 370
ESRHDFQVRV KVGKFVAKLT ERMFPKSQE
Length:379
Mass (Da):42,620
Last modified:March 1, 2003 - v1
Checksum:i6EA7B87544652055
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti4A → T in AAH11101 (PubMed:15489334).Curated1
Sequence conflicti53S → P in BAB23399 (PubMed:16141072).Curated1
Sequence conflicti68N → Y in BAB23399 (PubMed:16141072).Curated1
Sequence conflicti333L → P in BAB23399 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004598 mRNA. Translation: BAB23399.1.
AK030729 mRNA. Translation: BAC27102.1.
AL772348 Genomic DNA. Translation: CAM20585.1.
BC011101 mRNA. Translation: AAH11101.1.
BC051113 mRNA. Translation: AAH51113.1.
CCDSiCCDS30400.1.
RefSeqiNP_082146.2. NM_027870.3.
XP_006528672.1. XM_006528609.2.
XP_017174115.1. XM_017318626.1.
UniGeneiMm.67949.

Genome annotation databases

EnsembliENSMUST00000081834; ENSMUSP00000080518; ENSMUSG00000049047.
ENSMUST00000086880; ENSMUSP00000084093; ENSMUSG00000049047.
ENSMUST00000086884; ENSMUSP00000084097; ENSMUSG00000049047.
GeneIDi71703.
KEGGimmu:71703.
UCSCiuc009ugo.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004598 mRNA. Translation: BAB23399.1.
AK030729 mRNA. Translation: BAC27102.1.
AL772348 Genomic DNA. Translation: CAM20585.1.
BC011101 mRNA. Translation: AAH11101.1.
BC051113 mRNA. Translation: AAH51113.1.
CCDSiCCDS30400.1.
RefSeqiNP_082146.2. NM_027870.3.
XP_006528672.1. XM_006528609.2.
XP_017174115.1. XM_017318626.1.
UniGeneiMm.67949.

3D structure databases

ProteinModelPortaliQ8BHS6.
SMRiQ8BHS6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000080518.

PTM databases

iPTMnetiQ8BHS6.
PhosphoSitePlusiQ8BHS6.

Proteomic databases

EPDiQ8BHS6.
MaxQBiQ8BHS6.
PaxDbiQ8BHS6.
PeptideAtlasiQ8BHS6.
PRIDEiQ8BHS6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000081834; ENSMUSP00000080518; ENSMUSG00000049047.
ENSMUST00000086880; ENSMUSP00000084093; ENSMUSG00000049047.
ENSMUST00000086884; ENSMUSP00000084097; ENSMUSG00000049047.
GeneIDi71703.
KEGGimmu:71703.
UCSCiuc009ugo.2. mouse.

Organism-specific databases

CTDi51566.
MGIiMGI:1918953. Armcx3.

Phylogenomic databases

eggNOGiENOG410IVCU. Eukaryota.
ENOG4112958. LUCA.
GeneTreeiENSGT00550000074488.
HOGENOMiHOG000231611.
HOVERGENiHBG080349.
InParanoidiQ8BHS6.
OMAiCPGARYN.
OrthoDBiEOG091G0PCU.
PhylomeDBiQ8BHS6.
TreeFamiTF335652.

Miscellaneous databases

PROiQ8BHS6.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000049047.
CleanExiMM_ARMCX3.
GenevisibleiQ8BHS6. MM.

Family and domain databases

Gene3Di1.25.10.10. 2 hits.
InterProiIPR011989. ARM-like.
IPR006911. ARM-rpt_dom.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
[Graphical view]
PfamiPF04826. Arm_2. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50176. ARM_REPEAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiARMX3_MOUSE
AccessioniPrimary (citable) accession number: Q8BHS6
Secondary accession number(s): A2AKS4, Q91VP8, Q9DC32
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: March 1, 2003
Last modified: November 2, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.