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Protein

Dephospho-CoA kinase domain-containing protein

Gene

Dcakd

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi8 – 158ATPSequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Dephospho-CoA kinase domain-containing protein
Gene namesi
Name:Dcakd
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1915337. Dcakd.

Subcellular locationi

GO - Cellular componenti

  • membrane Source: MGI
  • mitochondrion Source: MGI
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 231231Dephospho-CoA kinase domain-containing proteinPRO_0000316850Add
BLAST

Proteomic databases

EPDiQ8BHC4.
MaxQBiQ8BHC4.
PaxDbiQ8BHC4.
PRIDEiQ8BHC4.

PTM databases

iPTMnetiQ8BHC4.
PhosphoSiteiQ8BHC4.

Expressioni

Gene expression databases

BgeeiQ8BHC4.
CleanExiMM_DCAKD.
ExpressionAtlasiQ8BHC4. baseline and differential.
GenevisibleiQ8BHC4. MM.

Interactioni

Protein-protein interaction databases

BioGridi212648. 1 interaction.
IntActiQ8BHC4. 1 interaction.
STRINGi10090.ENSMUSP00000021313.

Structurei

3D structure databases

ProteinModelPortaliQ8BHC4.
SMRiQ8BHC4. Positions 1-178.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini3 – 207205DPCKAdd
BLAST

Sequence similaritiesi

Belongs to the CoaE family.Curated

Phylogenomic databases

eggNOGiKOG3220. Eukaryota.
COG0237. LUCA.
GeneTreeiENSGT00550000075038.
HOGENOMiHOG000020768.
HOVERGENiHBG061063.
InParanoidiQ8BHC4.
OMAiRGKPAYN.
OrthoDBiEOG7353XT.
PhylomeDBiQ8BHC4.
TreeFamiTF314815.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00376. Dephospho_CoA_kinase.
InterProiIPR001977. Depp_CoAkinase.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01121. CoaE. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00152. TIGR00152. 1 hit.
PROSITEiPS51219. DPCK. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BHC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLVGLTGGI ASGKSSVIQV FQQLGCAVID VDVIARHVVQ PGYPAHRRIV
60 70 80 90 100
EAFGTEVLLE NGDIDRKVLG DLIFNQPDRR QLLNSITHPE IRKEMMKETF
110 120 130 140 150
KYFLRGYRYV ILDIPLLFET KKLLKYMKHT VVVYCDRDTQ LARLMKRNNL
160 170 180 190 200
NREDAEARIN AQLPLKDKAR MANHVLDNSG EWSLTRRQAI LLHAKLERSM
210 220 230
EYLPLRLGFL TGLAGIASLL YLLTRYLLPS P
Length:231
Mass (Da):26,476
Last modified:March 1, 2003 - v1
Checksum:i32F4E938C5234B48
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK051022 mRNA. Translation: BAC34499.1.
AK078460 mRNA. Translation: BAC37286.1.
AK162069 mRNA. Translation: BAE36709.1.
AK170762 mRNA. Translation: BAE42013.1.
AL731670 Genomic DNA. Translation: CAM25118.1.
BC005607 mRNA. Translation: AAH05607.1.
BC045193 mRNA. Translation: AAH45193.1.
CCDSiCCDS25510.1.
RefSeqiNP_080827.2. NM_026551.3.
XP_006534101.1. XM_006534038.2.
UniGeneiMm.277449.

Genome annotation databases

EnsembliENSMUST00000021313; ENSMUSP00000021313; ENSMUSG00000020935.
GeneIDi68087.
KEGGimmu:68087.
UCSCiuc007ltc.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK051022 mRNA. Translation: BAC34499.1.
AK078460 mRNA. Translation: BAC37286.1.
AK162069 mRNA. Translation: BAE36709.1.
AK170762 mRNA. Translation: BAE42013.1.
AL731670 Genomic DNA. Translation: CAM25118.1.
BC005607 mRNA. Translation: AAH05607.1.
BC045193 mRNA. Translation: AAH45193.1.
CCDSiCCDS25510.1.
RefSeqiNP_080827.2. NM_026551.3.
XP_006534101.1. XM_006534038.2.
UniGeneiMm.277449.

3D structure databases

ProteinModelPortaliQ8BHC4.
SMRiQ8BHC4. Positions 1-178.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi212648. 1 interaction.
IntActiQ8BHC4. 1 interaction.
STRINGi10090.ENSMUSP00000021313.

PTM databases

iPTMnetiQ8BHC4.
PhosphoSiteiQ8BHC4.

Proteomic databases

EPDiQ8BHC4.
MaxQBiQ8BHC4.
PaxDbiQ8BHC4.
PRIDEiQ8BHC4.

Protocols and materials databases

DNASUi68087.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000021313; ENSMUSP00000021313; ENSMUSG00000020935.
GeneIDi68087.
KEGGimmu:68087.
UCSCiuc007ltc.1. mouse.

Organism-specific databases

CTDi79877.
MGIiMGI:1915337. Dcakd.

Phylogenomic databases

eggNOGiKOG3220. Eukaryota.
COG0237. LUCA.
GeneTreeiENSGT00550000075038.
HOGENOMiHOG000020768.
HOVERGENiHBG061063.
InParanoidiQ8BHC4.
OMAiRGKPAYN.
OrthoDBiEOG7353XT.
PhylomeDBiQ8BHC4.
TreeFamiTF314815.

Miscellaneous databases

PROiQ8BHC4.
SOURCEiSearch...

Gene expression databases

BgeeiQ8BHC4.
CleanExiMM_DCAKD.
ExpressionAtlasiQ8BHC4. baseline and differential.
GenevisibleiQ8BHC4. MM.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00376. Dephospho_CoA_kinase.
InterProiIPR001977. Depp_CoAkinase.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01121. CoaE. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00152. TIGR00152. 1 hit.
PROSITEiPS51219. DPCK. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J and NOD.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N.
    Tissue: Eye and Mammary tumor.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Brain, Brown adipose tissue, Heart, Kidney, Liver, Lung, Pancreas, Spleen and Testis.

Entry informationi

Entry nameiDCAKD_MOUSE
AccessioniPrimary (citable) accession number: Q8BHC4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: March 1, 2003
Last modified: June 8, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.