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Q8BHB2

- Q8BHB2_MOUSE

UniProt

Q8BHB2 - Q8BHB2_MOUSE

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Protein
Submitted name: Putative uncharacterized protein
Gene
Ehmt1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: UniProtKB
  2. methyltransferase activity Source: UniProtKB
  3. zinc ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. chromatin modification Source: UniProtKB
  2. histone methylation Source: UniProtKB
  3. negative regulation of transcription from RNA polymerase II promoter Source: MGI
  4. peptidyl-lysine dimethylation Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Ehmt1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1924933. Ehmt1.

Subcellular locationi

GO - Cellular componenti

  1. chromosome Source: UniProtKB-KW
  2. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

ChromosomeSAAS annotations, NucleusSAAS annotations

Expressioni

Gene expression databases

GenevestigatoriQ8BHB2.

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 7 ANK repeats.UniRule annotation
Contains SET domain.SAAS annotations
Contains pre-SET domain.SAAS annotations

Keywords - Domaini

ANK repeatUniRule annotation, RepeatUniRule annotation

Phylogenomic databases

HOGENOMiHOG000231216.
HOVERGENiHBG028394.
InParanoidiQ8BHB2.
KOiK11420.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR007728. Pre-SET_dom.
IPR003606. Pre-SET_Zn-bd_sub.
IPR001214. SET_dom.
[Graphical view]
PfamiPF00023. Ank. 1 hit.
PF12796. Ank_2. 2 hits.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 7 hits.
SM00468. PreSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BHB2-1 [UniParc]FASTAAdd to Basket

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MSETDRAAKM DGDSEEEQES PDTGEDEDGG DESDLSSESS IKKKFLKRRG    50
KTDSPWIKPA RKRRRRSRKK PSSMLGSEAC KSSPGSMEQA ALGDSAGYME 100
VSLDSLDLRV RGILSSQTEN EGLASGPDVL GTDGLQEVPL CSCRMETPKS 150
REISTLANNQ CMATESVDHE LGRCTNSVVK YELMRPSNKA PLLVLCEDHR 200
GRMVKHQCCP GCGYFCTAGN FMECQPESSI SHRFHKDCAS RVNNASYCPH 250
CGEEASKAKE VTIAKADTTS TVTLAPGQEK SLAAEGRADT TTGSIAGAPE 300
DERSQSTAPQ APECFDPAGP AGLVRPTSGL SQGPGKETLE SALIALDSEK 350
PKKLRFHPKQ LYFSARQGEL QKVLLMLVDG IDPNFKMEHQ SKRSPLHAAA 400
EAGHVDICHM LVQAGANIDT CSEDQRTPLM EAAENNHLDA VKYLIKAGAQ 450
VDPKDAEGST CLHLAAKKGH YDVVQYLLSN GQMDVNCQDD GGWTPMIWAT 500
EYKHVELVKL LLSKGSDINI RDNEENICLH WAAFSGCVDI AEILLAAKCD 550
LHAVNIHGDS PLHIAARENR YDCVVLFLSR DSDVTLKNKE GETPLQCASL 600
SSQVWSALQM SKALRDSAPD KPVAVEKTVS RDIARGYERI PIPCVNAVDS 650
ELCPTNYKYV SQNCVTSPMN IDRNITHLQY CVCVDDCSSS TCMCGQLSMR 700
CWYDKDGRLL PEFNMAEPPL IFECNHACSC WRNCRNRVVQ NGLRARLQLY 750
RTQDMGWGVR SLQDIPLGTF VCEYVGELIS DSEADVREED SYLFDLDNKD 800
GEVYCIDARF YGNVSRFINH HCEPNLVPVR VFMSHQDLRF PRIAFFSTRL 850
IQAGEQLGFD YGERFWDVKG KLFSCRCGSS KCRHSSAALA QRQASAAQEP 900
QENGLPDTSS AAAADPL 917
Length:917
Mass (Da):101,018
Last modified:March 1, 2003 - v1
Checksum:i3925B0891108F2F8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK049454 mRNA. Translation: BAC33756.1.
AK052174 mRNA. Translation: BAC34869.1.
AK082062 mRNA. Translation: BAC38402.1.
RefSeqiNP_766133.2. NM_172545.4.
UniGeneiMm.24176.

Genome annotation databases

GeneIDi77683.
KEGGimmu:77683.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK049454 mRNA. Translation: BAC33756.1 .
AK052174 mRNA. Translation: BAC34869.1 .
AK082062 mRNA. Translation: BAC38402.1 .
RefSeqi NP_766133.2. NM_172545.4.
UniGenei Mm.24176.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 77683.
KEGGi mmu:77683.

Organism-specific databases

CTDi 79813.
MGIi MGI:1924933. Ehmt1.

Phylogenomic databases

HOGENOMi HOG000231216.
HOVERGENi HBG028394.
InParanoidi Q8BHB2.
KOi K11420.

Miscellaneous databases

NextBioi 347359.
SOURCEi Search...

Gene expression databases

Genevestigatori Q8BHB2.

Family and domain databases

Gene3Di 1.25.40.20. 1 hit.
InterProi IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR007728. Pre-SET_dom.
IPR003606. Pre-SET_Zn-bd_sub.
IPR001214. SET_dom.
[Graphical view ]
Pfami PF00023. Ank. 1 hit.
PF12796. Ank_2. 2 hits.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view ]
PRINTSi PR01415. ANKYRIN.
SMARTi SM00248. ANK. 7 hits.
SM00468. PreSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view ]
SUPFAMi SSF48403. SSF48403. 1 hit.
PROSITEi PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeadImported, HeartImported and Whole bodyImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeadImported, HeartImported and Whole bodyImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeadImported, HeartImported and Whole bodyImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeadImported, HeartImported and Whole bodyImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeartImported and Whole bodyImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeadImported, HeartImported and Whole bodyImported.
  7. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeadImported.
  8. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeadImported, HeartImported and Whole bodyImported.
  9. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeadImported, HeartImported and Whole bodyImported.

Entry informationi

Entry nameiQ8BHB2_MOUSE
AccessioniPrimary (citable) accession number: Q8BHB2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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