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Protein
Submitted name:

Vesicle-associated membrane protein, associated protein B and C

Gene

Vapb

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-1660661. Sphingolipid de novo biosynthesis.

Names & Taxonomyi

Protein namesi
Submitted name:
Vesicle-associated membrane protein, associated protein B and CImported
Submitted name:
Vesicle-associated membrane protein-associated protein BImported
Gene namesi
Name:VapbImported
ORF Names:mCG_13760Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1928744. Vapb.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei224 – 242HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000054455.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

MINTiMINT-4110487.
STRINGi10090.ENSMUSP00000064699.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 124MSPInterPro annotationAdd BLAST118

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili166 – 193Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0439. Eukaryota.
COG5066. LUCA.
GeneTreeiENSGT00390000006947.
HOVERGENiHBG028551.
KOiK10707.
OMAiVEINKIM.
OrthoDBiEOG091G0KJ2.
TreeFamiTF317024.

Family and domain databases

Gene3Di2.60.40.360. 1 hit.
InterProiIPR000535. MSP_dom.
IPR008962. PapD-like.
IPR016763. VAP.
IPR030226. VapB.
[Graphical view]
PANTHERiPTHR10809. PTHR10809. 1 hit.
PTHR10809:SF12. PTHR10809:SF12. 1 hit.
PfamiPF00635. Motile_Sperm. 1 hit.
[Graphical view]
PIRSFiPIRSF019693. VAMP-associated. 1 hit.
SUPFAMiSSF49354. SSF49354. 1 hit.
PROSITEiPS50202. MSP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BH80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKVEQVLSL EPQHELKFRG PFTDVVTTNL KLGNPTDRNV CFKVKTTAPR
60 70 80 90 100
RYCVRPNSGV IDAGASLNVS VMLQPFDYDP NEKSKHKFMV QSMFAPPDTS
110 120 130 140 150
DMEAVWKEAK PEDLMDSKLR CVFELPAENA KPHDVEINKI IPTSASKTEA
160 170 180 190 200
PAAAKSLTSP LDDTEVKKVM EECRRLQGEV QRLREESRQL KEEDGLRVRK
210 220 230 240
AMPSNSPVAA LAATGKEEGL SARLLALVVL FFIVGVIIGK IAL
Length:243
Mass (Da):26,918
Last modified:March 1, 2003 - v1
Checksum:i4353D945931C41C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844849 Genomic DNA. No translation available.
AL845503 Genomic DNA. No translation available.
BC048231 mRNA. Translation: AAH48231.1.
BC057123 mRNA. Translation: AAH57123.1.
AK050632 mRNA. Translation: BAC34353.1.
AK081908 mRNA. Translation: BAC38368.1.
CH466551 Genomic DNA. Translation: EDL06655.1.
RefSeqiNP_062780.2. NM_019806.5.
UniGeneiMm.260456.

Genome annotation databases

EnsembliENSMUST00000067530; ENSMUSP00000064699; ENSMUSG00000054455.
GeneIDi56491.
KEGGimmu:56491.
UCSCiuc008oei.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844849 Genomic DNA. No translation available.
AL845503 Genomic DNA. No translation available.
BC048231 mRNA. Translation: AAH48231.1.
BC057123 mRNA. Translation: AAH57123.1.
AK050632 mRNA. Translation: BAC34353.1.
AK081908 mRNA. Translation: BAC38368.1.
CH466551 Genomic DNA. Translation: EDL06655.1.
RefSeqiNP_062780.2. NM_019806.5.
UniGeneiMm.260456.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-4110487.
STRINGi10090.ENSMUSP00000064699.

Protocols and materials databases

DNASUi56491.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000067530; ENSMUSP00000064699; ENSMUSG00000054455.
GeneIDi56491.
KEGGimmu:56491.
UCSCiuc008oei.1. mouse.

Organism-specific databases

CTDi9217.
MGIiMGI:1928744. Vapb.

Phylogenomic databases

eggNOGiKOG0439. Eukaryota.
COG5066. LUCA.
GeneTreeiENSGT00390000006947.
HOVERGENiHBG028551.
KOiK10707.
OMAiVEINKIM.
OrthoDBiEOG091G0KJ2.
TreeFamiTF317024.

Enzyme and pathway databases

ReactomeiR-MMU-1660661. Sphingolipid de novo biosynthesis.

Miscellaneous databases

ChiTaRSiVapb. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000054455.

Family and domain databases

Gene3Di2.60.40.360. 1 hit.
InterProiIPR000535. MSP_dom.
IPR008962. PapD-like.
IPR016763. VAP.
IPR030226. VapB.
[Graphical view]
PANTHERiPTHR10809. PTHR10809. 1 hit.
PTHR10809:SF12. PTHR10809:SF12. 1 hit.
PfamiPF00635. Motile_Sperm. 1 hit.
[Graphical view]
PIRSFiPIRSF019693. VAMP-associated. 1 hit.
SUPFAMiSSF49354. SSF49354. 1 hit.
PROSITEiPS50202. MSP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8BH80_MOUSE
AccessioniPrimary (citable) accession number: Q8BH80
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: November 30, 2016
This is version 122 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.