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Q8BH40

- Q8BH40_MOUSE

UniProt

Q8BH40 - Q8BH40_MOUSE

Protein
Submitted name:

Syntaxin 7

Gene

Stx7

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 104 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein binding Source: MGI
    2. SNAP receptor activity Source: RefGenome
    3. SNARE binding Source: MGI

    GO - Biological processi

    1. intracellular protein transport Source: RefGenome
    2. synaptic vesicle exocytosis Source: RefGenome

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Syntaxin 7Imported
    Submitted name:
    Syntaxin-7Imported
    Gene namesi
    Name:Stx7Imported
    Synonyms:Stx-7Imported
    ORF Names:mCG_6753Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 10

    Organism-specific databases

    MGIiMGI:1858210. Stx7.

    Subcellular locationi

    GO - Cellular componenti

    1. lysosomal membrane Source: Ensembl
    2. perinuclear region of cytoplasm Source: MGI
    3. SNARE complex Source: RefGenome

    Expressioni

    Gene expression databases

    GenevestigatoriQ8BH40.

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-217183.
    STRINGi10090.ENSMUSP00000020174.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the syntaxin family.UniRule annotation
    Contains t-SNARE coiled-coil homology domain.SAAS annotation

    Keywords - Domaini

    Coiled coilSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00450000040239.
    HOVERGENiHBG053083.
    InParanoidiQ8BH40.
    KOiK08488.
    OMAiIIWGLNR.
    OrthoDBiEOG7B31PS.
    TreeFamiTF315607.

    Family and domain databases

    InterProiIPR006012. Syntaxin/epimorphin_CS.
    IPR006011. Syntaxin_N.
    IPR010989. t-SNARE.
    IPR000727. T_SNARE_dom.
    [Graphical view]
    PfamiPF05739. SNARE. 1 hit.
    [Graphical view]
    SMARTiSM00503. SynN. 1 hit.
    SM00397. t_SNARE. 1 hit.
    [Graphical view]
    SUPFAMiSSF47661. SSF47661. 1 hit.
    PROSITEiPS00914. SYNTAXIN. 1 hit.
    PS50192. T_SNARE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8BH40-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSYTPGIGGD SAQLAQRISS NIQKITQCSV EIQRTLNQLG TPQDSPELRQ    50
    QLQQKQQYTN QLAKETDKYI KEFGSLPTTP SEQRQRKIQK DRLVAEFTTS 100
    LTNFQKAQRQ AAEREKEFVA RVRASSRVSG GFPEDSSKEK NLVSWESQTQ 150
    PQVQVQDEEI TEDDLRLIHE RESSIRQLEA DIMDINEIFK DLGMMIHEQG 200
    DMIDSIEANV ESAEVHVQQA NQQLSRAADY QRKSRKTLCI IIFILVVGIV 250
    IICLIVWGLK G 261
    Length:261
    Mass (Da):29,737
    Last modified:March 1, 2003 - v1
    Checksum:i50D53C6011135E08
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC125010 Genomic DNA. No translation available.
    BC132123 mRNA. Translation: AAI32124.1.
    BC132125 mRNA. Translation: AAI32126.1.
    AB084949 Genomic DNA. Translation: BAC23139.1.
    AK082927 mRNA. Translation: BAC38695.1.
    AK142742 mRNA. Translation: BAE25180.1.
    AK158923 mRNA. Translation: BAE34729.1.
    AK166822 mRNA. Translation: BAE39048.1.
    AK169822 mRNA. Translation: BAE41392.1.
    CH466540 Genomic DNA. Translation: EDL04780.1.
    RefSeqiNP_058077.2. NM_016797.4.
    XP_006512863.1. XM_006512800.1.
    XP_006512864.1. XM_006512801.1.
    UniGeneiMm.248042.

    Genome annotation databases

    EnsembliENSMUST00000020174; ENSMUSP00000020174; ENSMUSG00000019998.
    GeneIDi53331.
    KEGGimmu:53331.
    UCSCiuc007eqs.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC125010 Genomic DNA. No translation available.
    BC132123 mRNA. Translation: AAI32124.1 .
    BC132125 mRNA. Translation: AAI32126.1 .
    AB084949 Genomic DNA. Translation: BAC23139.1 .
    AK082927 mRNA. Translation: BAC38695.1 .
    AK142742 mRNA. Translation: BAE25180.1 .
    AK158923 mRNA. Translation: BAE34729.1 .
    AK166822 mRNA. Translation: BAE39048.1 .
    AK169822 mRNA. Translation: BAE41392.1 .
    CH466540 Genomic DNA. Translation: EDL04780.1 .
    RefSeqi NP_058077.2. NM_016797.4.
    XP_006512863.1. XM_006512800.1.
    XP_006512864.1. XM_006512801.1.
    UniGenei Mm.248042.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-217183.
    STRINGi 10090.ENSMUSP00000020174.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000020174 ; ENSMUSP00000020174 ; ENSMUSG00000019998 .
    GeneIDi 53331.
    KEGGi mmu:53331.
    UCSCi uc007eqs.1. mouse.

    Organism-specific databases

    CTDi 8417.
    MGIi MGI:1858210. Stx7.

    Phylogenomic databases

    GeneTreei ENSGT00450000040239.
    HOVERGENi HBG053083.
    InParanoidi Q8BH40.
    KOi K08488.
    OMAi IIWGLNR.
    OrthoDBi EOG7B31PS.
    TreeFami TF315607.

    Miscellaneous databases

    ChiTaRSi STX7. mouse.
    NextBioi 310153.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q8BH40.

    Family and domain databases

    InterProi IPR006012. Syntaxin/epimorphin_CS.
    IPR006011. Syntaxin_N.
    IPR010989. t-SNARE.
    IPR000727. T_SNARE_dom.
    [Graphical view ]
    Pfami PF05739. SNARE. 1 hit.
    [Graphical view ]
    SMARTi SM00503. SynN. 1 hit.
    SM00397. t_SNARE. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47661. SSF47661. 1 hit.
    PROSITEi PS00914. SYNTAXIN. 1 hit.
    PS50192. T_SNARE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and NODImported.
      Tissue: HeartImported, ThymusImported, Visual cortexImported and Whole bodyImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and NODImported.
      Tissue: HeartImported, ThymusImported, Visual cortexImported and Whole bodyImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and NODImported.
      Tissue: HeartImported, ThymusImported, Visual cortexImported and Whole bodyImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and NODImported.
      Tissue: HeartImported, ThymusImported, Visual cortexImported and Whole bodyImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and NODImported.
      Tissue: HeartImported, ThymusImported, Visual cortexImported and Whole bodyImported.
    6. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    7. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.
    8. "mouse syntaxin-7 locus."
      Wada Y., Futai M.
      Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 129SvImported.
    9. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: BrainImported.
    10. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    11. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HeartImported and Visual cortexImported.
    12. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and NODImported.
      Tissue: ThymusImported.
    13. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and NODImported.
      Tissue: HeartImported, ThymusImported, Visual cortexImported and Whole bodyImported.
    14. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and NODImported.
      Tissue: HeartImported, ThymusImported, Visual cortexImported and Whole bodyImported.
    15. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    16. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    17. "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
      Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    18. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    19. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ8BH40_MOUSE
    AccessioniPrimary (citable) accession number: Q8BH40
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 104 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3