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Protein
Submitted name:

Alpha-galactosidase A

Gene

Gla

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationSAAS annotation, Hydrolase

Enzyme and pathway databases

ReactomeiR-MMU-1660662. Glycosphingolipid metabolism.

Protein family/group databases

CAZyiGH27. Glycoside Hydrolase Family 27.

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-galactosidase AImported
Gene namesi
Name:GlaImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:1347344. Gla.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000031266.

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000033621.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 27 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2366. Eukaryota.
ENOG410XPF1. LUCA.
GeneTreeiENSGT00390000008751.
HOVERGENiHBG001989.
KOiK01189.
OMAiWASVRTI.
OrthoDBiEOG091G0BGV.
TreeFamiTF312909.

Family and domain databases

CDDicd14792. GH27. 1 hit.
Gene3Di2.60.40.1180. 1 hit.
3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR002241. Glyco_hydro_27.
IPR000111. Glyco_hydro_27/36_CS.
IPR013780. Glyco_hydro_b.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF16499. Melibiase_2. 1 hit.
[Graphical view]
PRINTSiPR00740. GLHYDRLASE27.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00512. ALPHA_GALACTOSIDASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BGZ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMKLLSRDT RLVCELALCP LALVFWSILG VRALDNGLAR TPTMGWLHWE
60 70 80 90 100
RFMCNLDCQE EPDACISEQL FMQMAELMVS DGWRDAGYDY LCIDDCWMAP
110 120 130 140 150
ERDSKGRLQA DPQRFPSGIK HLANYVHSKG LKLGIYADVG NKTCAGFPGS
160 170 180 190 200
FGSYDIDAQT FADWGVDLLK FDGCHCDSVV SLENGYKYMA LALNRTGRSI
210 220 230 240 250
VYSCEWPLYL RPFHKPNYTD IQYYCNHWRN FDDVYDSWES IKNILSWTVV
260 270 280 290 300
YQKEIVEVAG PGSWNDPDML VIGNFGLSWD QQVTQMALWA IMAAPLLMSN
310 320 330 340 350
DLRQISSQAK ALLQNKDVIA INQDPLGKQG YCFRKENHIE VWERPLSNLA
360 370 380 390 400
WAVAVRNLQE IGGPCPYTIQ ISSLGRGLAC NPGCIITQLL PEKVHLGFYE
410 420
WTLTLKTRVN PSGTVLFRLE R
Length:421
Mass (Da):47,845
Last modified:March 1, 2003 - v1
Checksum:i5F66772334014B6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX004852 Genomic DNA. No translation available.
AK040081 mRNA. Translation: BAC30508.1.
AK054547 mRNA. Translation: BAC35819.1.
AK164231 mRNA. Translation: BAE37692.1.
RefSeqiNP_038491.2. NM_013463.2.
UniGeneiMm.1114.

Genome annotation databases

EnsembliENSMUST00000033621; ENSMUSP00000033621; ENSMUSG00000031266.
GeneIDi11605.
KEGGimmu:11605.
UCSCiuc009ugg.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX004852 Genomic DNA. No translation available.
AK040081 mRNA. Translation: BAC30508.1.
AK054547 mRNA. Translation: BAC35819.1.
AK164231 mRNA. Translation: BAE37692.1.
RefSeqiNP_038491.2. NM_013463.2.
UniGeneiMm.1114.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000033621.

Protein family/group databases

CAZyiGH27. Glycoside Hydrolase Family 27.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000033621; ENSMUSP00000033621; ENSMUSG00000031266.
GeneIDi11605.
KEGGimmu:11605.
UCSCiuc009ugg.1. mouse.

Organism-specific databases

CTDi2717.
MGIiMGI:1347344. Gla.

Phylogenomic databases

eggNOGiKOG2366. Eukaryota.
ENOG410XPF1. LUCA.
GeneTreeiENSGT00390000008751.
HOVERGENiHBG001989.
KOiK01189.
OMAiWASVRTI.
OrthoDBiEOG091G0BGV.
TreeFamiTF312909.

Enzyme and pathway databases

ReactomeiR-MMU-1660662. Glycosphingolipid metabolism.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000031266.

Family and domain databases

CDDicd14792. GH27. 1 hit.
Gene3Di2.60.40.1180. 1 hit.
3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR002241. Glyco_hydro_27.
IPR000111. Glyco_hydro_27/36_CS.
IPR013780. Glyco_hydro_b.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF16499. Melibiase_2. 1 hit.
[Graphical view]
PRINTSiPR00740. GLHYDRLASE27.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00512. ALPHA_GALACTOSIDASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8BGZ6_MOUSE
AccessioniPrimary (citable) accession number: Q8BGZ6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 7, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.