Q8BGZ6 (Q8BGZ6_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Galactosidase, alpha EMBL CAM19137.1

Submitted name:
Uncharacterized protein Ensembl ENSMUSP00000033621

Gene names

Name:	Gla MGI 1347344 Ensembl ENSMUSP00000033621
ORF Names:	RP23-26D22.3-001 EMBL CAM19137.1

Organism

Mus musculus (Mouse) EMBL BAC30508.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	421 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Glycosidase SAAS SAAS000111 Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycoside catabolic process Inferred from Biological aspect of Ancestor. Source: RefGenome glycosylceramide catabolic process Inferred from direct assay. Source: MGI oligosaccharide metabolic process Inferred from Biological aspect of Ancestor. Source: RefGenome
Cellular component	lysosome Inferred from direct assay. Source: MGI
Molecular function	alpha-galactosidase activity Inferred from direct assay. Source: MGI cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8BGZ6 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 5F66772334014B6F	FASTA	421	47,845
	10 20 30 40 50 60 MAMKLLSRDT RLVCELALCP LALVFWSILG VRALDNGLAR TPTMGWLHWE RFMCNLDCQE 70 80 90 100 110 120 EPDACISEQL FMQMAELMVS DGWRDAGYDY LCIDDCWMAP ERDSKGRLQA DPQRFPSGIK 130 140 150 160 170 180 HLANYVHSKG LKLGIYADVG NKTCAGFPGS FGSYDIDAQT FADWGVDLLK FDGCHCDSVV 190 200 210 220 230 240 SLENGYKYMA LALNRTGRSI VYSCEWPLYL RPFHKPNYTD IQYYCNHWRN FDDVYDSWES 250 260 270 280 290 300 IKNILSWTVV YQKEIVEVAG PGSWNDPDML VIGNFGLSWD QQVTQMALWA IMAAPLLMSN 310 320 330 340 350 360 DLRQISSQAK ALLQNKDVIA INQDPLGKQG YCFRKENHIE VWERPLSNLA WAVAVRNLQE 370 380 390 400 410 420 IGGPCPYTIQ ISSLGRGLAC NPGCIITQLL PEKVHLGFYE WTLTLKTRVN PSGTVLFRLE R

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed: 16141073] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC30508.1. Tissue: Ovary EMBL BAC35819.1, Thymus EMBL BAC30508.1 and Whole body EMBL BAE37692.1.
[2]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed: 11076861] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC30508.1. Tissue: Ovary EMBL BAC35819.1, Thymus EMBL BAC30508.1 and Whole body EMBL BAE37692.1.
[3]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Mouse Genome Sequencing Consortium Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed: 19468303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6 Ensembl ENSMUSP00000033621.
[4]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC30508.1. Tissue: Ovary EMBL BAC35819.1, Thymus EMBL BAC30508.1 and Whole body EMBL BAE37692.1.
[5]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed: 10349636] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC30508.1. Tissue: Ovary EMBL BAC35819.1, Thymus EMBL BAC30508.1 and Whole body EMBL BAE37692.1.
[6]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed: 11042159] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC30508.1. Tissue: Ovary EMBL BAC35819.1, Thymus EMBL BAC30508.1 and Whole body EMBL BAE37692.1.
[7]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC30508.1. Tissue: Ovary EMBL BAC35819.1, Thymus EMBL BAC30508.1 and Whole body EMBL BAE37692.1.
[8]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC30508.1. Tissue: Ovary EMBL BAC35819.1, Thymus EMBL BAC30508.1 and Whole body EMBL BAE37692.1.
[9]	Howden P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[10]	Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y. Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE37692.1. Tissue: Whole body EMBL BAE37692.1.
[11]	Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P., Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W., Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T., Hori F., Imotani K. , Ishii Y., Itoh M., Kagawa I., Kasukawa T., Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M., Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y., Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H., Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M., Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T., Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y. Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC30508.1. Tissue: Ovary EMBL BAC35819.1 and Thymus EMBL BAC30508.1.
[12]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000033621.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK040081 mRNA. Translation: BAC30508.1. AK054547 mRNA. Translation: BAC35819.1. AK164231 mRNA. Translation: BAE37692.1. BX004852 Genomic DNA. Translation: CAM19137.1.
IPI	IPI00123814.
RefSeq	NP_038491.2. NM_013463.2.
UniGene	Mm.1114.
3D structure databases
HSSP	HSSP built from PDB template 1R46 based on UniProtKB P06280.
ProteinModelPortal	Q8BGZ6.
SMR	Q8BGZ6. Positions 34-420.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8BGZ6.
Protein family/group databases
CAZy	GH27. Glycoside Hydrolase Family 27.
Proteomic databases
PRIDE	Q8BGZ6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000033621; ENSMUSP00000033621; ENSMUSG00000031266.
GeneID	11605.
KEGG	mmu:11605.
UCSC	uc009ugg.1. mouse.
Organism-specific databases
CTD	2717.
MGI	MGI:1347344. Gla.
Phylogenomic databases
GeneTree	ENSGT00390000008751.
HOVERGEN	HBG001989.
InParanoid	Q8BGZ6.
OMA	HISPQAK.
PhylomeDB	Q8BGZ6.
Gene expression databases
ArrayExpress	Q8BGZ6.
Bgee	Q8BGZ6.
Genevestigator	Q8BGZ6.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR013780. Glyco_hydro_13_b. IPR002241. Glyco_hydro_27. IPR000111. Glyco_hydro_GHD. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit. G3DSA:2.60.40.1180. Glyco_hydro_13_b. 1 hit.
KO	K01189.
Pfam	PF02065. Melibiase. 1 hit. [Graphical view]
PRINTS	PR00740. GLHYDRLASE27.
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
PROSITE	PS00512. ALPHA_GALACTOSIDASE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	279136.
SOURCE	Search...

Entry information

Entry name

Q8BGZ6_MOUSE

Accession

Primary (citable) accession number: Q8BGZ6

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	November 16, 2011
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)