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Protein
Submitted name:

Calcium/calmodulin-dependent protein kinase IV

Gene

Camk4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseUniRule annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-MMU-111932. CaMK IV-mediated phosphorylation of CREB.
R-MMU-442717. CREB phosphorylation through the activation of CaMKK.
R-MMU-442745. Activation of CaMK IV.

Names & Taxonomyi

Protein namesi
Submitted name:
Calcium/calmodulin-dependent protein kinase IVImported
Submitted name:
Calcium/calmodulin-dependent protein kinase IV, isoform CRA_aImported
Submitted name:
Calcium/calmodulin-dependent protein kinase type IVImported
Gene namesi
Name:Camk4Imported
ORF Names:mCG_140514Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:88258. Camk4.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSMUSG00000038128.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000046539.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 296Protein kinaseInterPro annotationAdd BLAST255

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0032. Eukaryota.
ENOG410XRMJ. LUCA.
GeneTreeiENSGT00760000118944.
HOVERGENiHBG108055.
KOiK05869.
OMAiWIDGSNK.
OrthoDBiEOG091G0HK9.
TreeFamiTF351230.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BGR3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKVTVPSCP SSPCSSVTAS TENLVPDYWI DGSNRDPLGD FFEVESELGR
60 70 80 90 100
GATSIVYRCK QKGTQKPYAL KVLKKTVDKK IVRTEIGVLL RLSHPNIIKL
110 120 130 140 150
KEIFETPTEI SLVLELVTGG ELFDRIVEKG YYSERDAADA VKQILEAVAY
160 170 180 190 200
LHENGIVHRD LKPENLLYAT PAPDAPLKIA DFGLSKIVEH QVLMKTVCGT
210 220 230 240 250
PGYCAPEILR GCAYGPEVDM WSVGIITYIL LCGFEPFYDE RGDQFMFRRI
260 270 280 290 300
LNCEYYFISP WWDEVSLNAK DLVKKLIVLD PKKRLTTFQA LQHPWVTGKA
310 320 330 340 350
ANFVHMDTAQ KKLQEFNARR KLKAAVKAVV ASSRLGSASS SHTSIQENHK
360 370 380 390 400
ASSDPPSTQD AKDSTDLLGK KMQEEDQEED QVEAEASADE MRKLQSEEVE
410 420 430 440 450
KDAGVKEEET SSMVPQDPED ELETDDPEMK RDSEEKLKSV EEEMDPMTEE
460
EAPDAGLGVP QQDAIQPEY
Length:469
Mass (Da):52,542
Last modified:March 1, 2003 - v1
Checksum:i7A83F684FB1CDFD6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC114919 Genomic DNA. No translation available.
AC132368 Genomic DNA. No translation available.
AC140983 Genomic DNA. No translation available.
BC070420 mRNA. Translation: AAH70420.1.
AK030219 mRNA. Translation: BAC26850.1.
AK043114 mRNA. Translation: BAC31462.1.
CH466557 Genomic DNA. Translation: EDK97068.1.
RefSeqiNP_033923.2. NM_009793.3.
XP_006525607.1. XM_006525544.3.
XP_006525609.1. XM_006525546.3.
UniGeneiMm.222329.
Mm.410854.

Genome annotation databases

EnsembliENSMUST00000042868; ENSMUSP00000046539; ENSMUSG00000038128.
GeneIDi12326.
KEGGimmu:12326.
UCSCiuc008ejq.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC114919 Genomic DNA. No translation available.
AC132368 Genomic DNA. No translation available.
AC140983 Genomic DNA. No translation available.
BC070420 mRNA. Translation: AAH70420.1.
AK030219 mRNA. Translation: BAC26850.1.
AK043114 mRNA. Translation: BAC31462.1.
CH466557 Genomic DNA. Translation: EDK97068.1.
RefSeqiNP_033923.2. NM_009793.3.
XP_006525607.1. XM_006525544.3.
XP_006525609.1. XM_006525546.3.
UniGeneiMm.222329.
Mm.410854.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000046539.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000042868; ENSMUSP00000046539; ENSMUSG00000038128.
GeneIDi12326.
KEGGimmu:12326.
UCSCiuc008ejq.2. mouse.

Organism-specific databases

CTDi814.
MGIiMGI:88258. Camk4.

Phylogenomic databases

eggNOGiKOG0032. Eukaryota.
ENOG410XRMJ. LUCA.
GeneTreeiENSGT00760000118944.
HOVERGENiHBG108055.
KOiK05869.
OMAiWIDGSNK.
OrthoDBiEOG091G0HK9.
TreeFamiTF351230.

Enzyme and pathway databases

ReactomeiR-MMU-111932. CaMK IV-mediated phosphorylation of CREB.
R-MMU-442717. CREB phosphorylation through the activation of CaMKK.
R-MMU-442745. Activation of CaMK IV.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000038128.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8BGR3_MOUSE
AccessioniPrimary (citable) accession number: Q8BGR3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 5, 2016
This is version 135 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.