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Q8BGJ5

- Q8BGJ5_MOUSE

UniProt

Q8BGJ5 - Q8BGJ5_MOUSE

Protein
Submitted name:

MCG13402, isoform CRA_a

Gene

Ptbp1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 102 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. nucleotide binding Source: InterPro
    2. protein binding Source: MGI
    3. RNA binding Source: InterPro

    GO - Biological processi

    1. mRNA processing Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MCG13402, isoform CRA_aImported
    Submitted name:
    Polypyrimidine tract-binding protein 1Imported
    Gene namesi
    Name:Ptbp1Imported
    ORF Names:mCG_13402Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 10

    Organism-specific databases

    MGIiMGI:97791. Ptbp1.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: MGI

    Expressioni

    Gene expression databases

    GenevestigatoriQ8BGJ5.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00550000074508.
    HOVERGENiHBG069548.
    KOiK13218.

    Family and domain databases

    Gene3Di3.30.70.330. 4 hits.
    InterProiIPR006536. HnRNP-L_PTB.
    IPR012677. Nucleotide-bd_a/b_plait.
    IPR000504. RRM_dom.
    [Graphical view]
    SMARTiSM00360. RRM. 4 hits.
    [Graphical view]
    TIGRFAMsiTIGR01649. hnRNP-L_PTB. 2 hits.
    PROSITEiPS50102. RRM. 4 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8BGJ5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDGIVPDIAV GTKRGSDELF STCVSNGPFI MSSSASAANG NDSKKFKGDN    50
    RSAGVPSRVI HVRKLPSDVT EGEVISLGLP FGKVTNLLML KGKNQAFIEM 100
    NTEEAANTMV NYYTSVAPVL RGQPIYIQFS NHKELKTDSS PNQARAQAAL 150
    QAVNSVQSGN LALAASAAAV DAGMAMAGQS PVLRIIVENL FYPVTLDVLH 200
    QIFSKFGTVL KIITFTKNNQ FQALLQYADP VSAQHAKLSL DGQNIYNACC 250
    TLRIDFSKLT SLNVKYNNDK SRDYTRPDLP SGDSQPSLDQ TMAAAFGLSV 300
    PNVHGALAPL AIPSAAAAAA ASRIAIPGLA GAGNSVLLVS NLNPERVTPQ 350
    SLFILFGVYG DVQRVKILFN KKENALVQMA DGSQAQLAMS HLNGHKLHGK 400
    SVRITLSKHQ SVQLPREGQE DQGLTKDYGS SPLHRFKKPG SKNFQNIFPP 450
    SATLHLSNIP PSVSEDDLKS LFSSNGGVVK GFKFFQKDRK MALIQMGSVE 500
    EAVQALIELH NHDLGENHHL RVSFSKSTI 529
    Length:529
    Mass (Da):56,892
    Last modified:March 1, 2003 - v1
    Checksum:i92244CDC02A415F7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC151846 Genomic DNA. No translation available.
    AK044956 mRNA. Translation: BAC32158.1.
    AK051669 mRNA. Translation: BAC34712.1.
    AK082600 mRNA. Translation: BAC38544.1.
    AK149941 mRNA. Translation: BAE29183.1.
    AK168359 mRNA. Translation: BAE40295.1.
    CH466553 Genomic DNA. Translation: EDL31643.1.
    CH466553 Genomic DNA. Translation: EDL31645.1.
    RefSeqiNP_032982.2. NM_008956.3.
    UniGeneiMm.265610.

    Genome annotation databases

    EnsembliENSMUST00000165704; ENSMUSP00000127783; ENSMUSG00000006498.
    GeneIDi19205.
    KEGGimmu:19205.
    UCSCiuc007gac.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC151846 Genomic DNA. No translation available.
    AK044956 mRNA. Translation: BAC32158.1 .
    AK051669 mRNA. Translation: BAC34712.1 .
    AK082600 mRNA. Translation: BAC38544.1 .
    AK149941 mRNA. Translation: BAE29183.1 .
    AK168359 mRNA. Translation: BAE40295.1 .
    CH466553 Genomic DNA. Translation: EDL31643.1 .
    CH466553 Genomic DNA. Translation: EDL31645.1 .
    RefSeqi NP_032982.2. NM_008956.3.
    UniGenei Mm.265610.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000165704 ; ENSMUSP00000127783 ; ENSMUSG00000006498 .
    GeneIDi 19205.
    KEGGi mmu:19205.
    UCSCi uc007gac.1. mouse.

    Organism-specific databases

    CTDi 5725.
    MGIi MGI:97791. Ptbp1.

    Phylogenomic databases

    GeneTreei ENSGT00550000074508.
    HOVERGENi HBG069548.
    KOi K13218.

    Miscellaneous databases

    ChiTaRSi PTBP1. mouse.
    NextBioi 295932.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q8BGJ5.

    Family and domain databases

    Gene3Di 3.30.70.330. 4 hits.
    InterProi IPR006536. HnRNP-L_PTB.
    IPR012677. Nucleotide-bd_a/b_plait.
    IPR000504. RRM_dom.
    [Graphical view ]
    SMARTi SM00360. RRM. 4 hits.
    [Graphical view ]
    TIGRFAMsi TIGR01649. hnRNP-L_PTB. 2 hits.
    PROSITEi PS50102. RRM. 4 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and DBA/2Imported.
      Tissue: Bone marrowImported, CerebellumImported, ParthenogenoteImported and Spinal ganglionImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and DBA/2Imported.
      Tissue: Bone marrowImported, CerebellumImported, ParthenogenoteImported and Spinal ganglionImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and DBA/2Imported.
      Tissue: Bone marrowImported, CerebellumImported, ParthenogenoteImported and Spinal ganglionImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and DBA/2Imported.
      Tissue: Bone marrowImported, CerebellumImported, ParthenogenoteImported and Spinal ganglionImported.
    5. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: ParthenogenoteImported and Spinal ganglionImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and DBA/2Imported.
      Tissue: Bone marrowImported, CerebellumImported, ParthenogenoteImported and Spinal ganglionImported.
    7. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: CerebellumImported.
    9. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Bone marrowImported.
    10. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: DBA/2Imported.
    11. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and DBA/2Imported.
      Tissue: Bone marrowImported, CerebellumImported, ParthenogenoteImported and Spinal ganglionImported.
    12. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported and DBA/2Imported.
      Tissue: Bone marrowImported, CerebellumImported, ParthenogenoteImported and Spinal ganglionImported.
    13. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    14. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    15. Ensembl
      Submitted (JUN-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.
    16. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
      Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiQ8BGJ5_MOUSE
    AccessioniPrimary (citable) accession number: Q8BGJ5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 102 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3