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Q8BGI1

- RNF24_MOUSE

UniProt

Q8BGI1 - RNF24_MOUSE

Protein

RING finger protein 24

Gene

Rnf24

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    May play a role in TRPCs intracellular trafficking.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri78 – 11942RING-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. zinc ion binding Source: InterPro

    Keywords - Ligandi

    Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RING finger protein 24
    Gene namesi
    Name:Rnf24
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 2

    Organism-specific databases

    MGIiMGI:1261771. Rnf24.

    Subcellular locationi

    GO - Cellular componenti

    1. Golgi membrane Source: UniProtKB-SubCell
    2. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Golgi apparatus, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 148148RING finger protein 24PRO_0000056064Add
    BLAST

    Proteomic databases

    PRIDEiQ8BGI1.

    PTM databases

    PhosphoSiteiQ8BGI1.

    Expressioni

    Gene expression databases

    ArrayExpressiQ8BGI1.
    BgeeiQ8BGI1.
    CleanExiMM_RNF24.
    GenevestigatoriQ8BGI1.

    Interactioni

    Subunit structurei

    Interacts with TRPC1, TRPC3, TRPC4, TRPC5, TRPC6 and TRPC7.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ8BGI1.
    SMRiQ8BGI1. Positions 68-128.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei24 – 4421HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 RING-type zinc finger.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri78 – 11942RING-typePROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Transmembrane, Transmembrane helix, Zinc-finger

    Phylogenomic databases

    eggNOGiNOG299260.
    GeneTreeiENSGT00710000106755.
    HOGENOMiHOG000004806.
    HOVERGENiHBG058899.
    InParanoidiQ8BGI1.
    OMAiPHYSFRM.
    OrthoDBiEOG7XDBHK.
    PhylomeDBiQ8BGI1.

    Family and domain databases

    Gene3Di3.30.40.10. 1 hit.
    InterProiIPR001841. Znf_RING.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view]
    PfamiPF13639. zf-RING_2. 1 hit.
    [Graphical view]
    SMARTiSM00184. RING. 1 hit.
    [Graphical view]
    PROSITEiPS50089. ZF_RING_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8BGI1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSDFPHYNF RMPNIGFQNL PLNIYIVVFG TAVFVFILSL LFCCYLIRLR    50
    HQAHKEFYAY KQVILKEKVK ELNLHELCAV CLEDFKPRDE LGICPCKHAF 100
    HRKCLVKWLE VRKVCPLCNM PVLQLAQLHS KQDRGPPQEP LPGAENIV 148
    Length:148
    Mass (Da):17,254
    Last modified:March 1, 2003 - v1
    Checksum:i96DFD3E31B6CC5C8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK048813 mRNA. Translation: BAC33467.1.
    AK083665 mRNA. Translation: BAC38987.1.
    AK089207 mRNA. Translation: BAC40793.1.
    CCDSiCCDS16762.1.
    RefSeqiNP_848722.1. NM_178607.4.
    XP_006499956.1. XM_006499893.1.
    UniGeneiMm.477523.

    Genome annotation databases

    EnsembliENSMUST00000059372; ENSMUSP00000058630; ENSMUSG00000048911.
    ENSMUST00000110194; ENSMUSP00000105823; ENSMUSG00000048911.
    ENSMUST00000165420; ENSMUSP00000129843; ENSMUSG00000048911.
    GeneIDi51902.
    KEGGimmu:51902.
    UCSCiuc008mlk.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK048813 mRNA. Translation: BAC33467.1 .
    AK083665 mRNA. Translation: BAC38987.1 .
    AK089207 mRNA. Translation: BAC40793.1 .
    CCDSi CCDS16762.1.
    RefSeqi NP_848722.1. NM_178607.4.
    XP_006499956.1. XM_006499893.1.
    UniGenei Mm.477523.

    3D structure databases

    ProteinModelPortali Q8BGI1.
    SMRi Q8BGI1. Positions 68-128.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q8BGI1.

    Proteomic databases

    PRIDEi Q8BGI1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000059372 ; ENSMUSP00000058630 ; ENSMUSG00000048911 .
    ENSMUST00000110194 ; ENSMUSP00000105823 ; ENSMUSG00000048911 .
    ENSMUST00000165420 ; ENSMUSP00000129843 ; ENSMUSG00000048911 .
    GeneIDi 51902.
    KEGGi mmu:51902.
    UCSCi uc008mlk.1. mouse.

    Organism-specific databases

    CTDi 11237.
    MGIi MGI:1261771. Rnf24.

    Phylogenomic databases

    eggNOGi NOG299260.
    GeneTreei ENSGT00710000106755.
    HOGENOMi HOG000004806.
    HOVERGENi HBG058899.
    InParanoidi Q8BGI1.
    OMAi PHYSFRM.
    OrthoDBi EOG7XDBHK.
    PhylomeDBi Q8BGI1.

    Miscellaneous databases

    NextBioi 308218.
    PROi Q8BGI1.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8BGI1.
    Bgeei Q8BGI1.
    CleanExi MM_RNF24.
    Genevestigatori Q8BGI1.

    Family and domain databases

    Gene3Di 3.30.40.10. 1 hit.
    InterProi IPR001841. Znf_RING.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view ]
    Pfami PF13639. zf-RING_2. 1 hit.
    [Graphical view ]
    SMARTi SM00184. RING. 1 hit.
    [Graphical view ]
    PROSITEi PS50089. ZF_RING_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J and NOD.
      Tissue: Cerebellum and Embryo.

    Entry informationi

    Entry nameiRNF24_MOUSE
    AccessioniPrimary (citable) accession number: Q8BGI1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2005
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3