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Protein

RING finger protein 24

Gene

Rnf24

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in TRPCs intracellular trafficking.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri78 – 119RING-typePROSITE-ProRule annotationAdd BLAST42

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
RING finger protein 24
Gene namesi
Name:Rnf24
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1261771. Rnf24.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei24 – 44HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000560641 – 148RING finger protein 24Add BLAST148

Proteomic databases

MaxQBiQ8BGI1.
PaxDbiQ8BGI1.
PRIDEiQ8BGI1.

PTM databases

iPTMnetiQ8BGI1.
PhosphoSitePlusiQ8BGI1.

Expressioni

Gene expression databases

BgeeiENSMUSG00000048911.
CleanExiMM_RNF24.
ExpressionAtlasiQ8BGI1. baseline and differential.
GenevisibleiQ8BGI1. MM.

Interactioni

Subunit structurei

Interacts with TRPC1, TRPC3, TRPC4, TRPC5, TRPC6 and TRPC7.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000058630.

Structurei

3D structure databases

ProteinModelPortaliQ8BGI1.
SMRiQ8BGI1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri78 – 119RING-typePROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

Transmembrane, Transmembrane helix, Zinc-finger

Phylogenomic databases

eggNOGiKOG0800. Eukaryota.
ENOG41121N2. LUCA.
GeneTreeiENSGT00710000106755.
HOGENOMiHOG000004806.
HOVERGENiHBG058899.
InParanoidiQ8BGI1.
OMAiHEICAVC.
OrthoDBiEOG091G0PFG.
PhylomeDBiQ8BGI1.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiView protein in InterPro
IPR001841. Znf_RING.
IPR011016. Znf_RING-CH.
IPR013083. Znf_RING/FYVE/PHD.
PfamiView protein in Pfam
PF13639. zf-RING_2. 1 hit.
SMARTiView protein in SMART
SM00184. RING. 1 hit.
SM00744. RINGv. 1 hit.
PROSITEiView protein in PROSITE
PS50089. ZF_RING_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8BGI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSDFPHYNF RMPNIGFQNL PLNIYIVVFG TAVFVFILSL LFCCYLIRLR
60 70 80 90 100
HQAHKEFYAY KQVILKEKVK ELNLHELCAV CLEDFKPRDE LGICPCKHAF
110 120 130 140
HRKCLVKWLE VRKVCPLCNM PVLQLAQLHS KQDRGPPQEP LPGAENIV
Length:148
Mass (Da):17,254
Last modified:March 1, 2003 - v1
Checksum:i96DFD3E31B6CC5C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK048813 mRNA. Translation: BAC33467.1.
AK083665 mRNA. Translation: BAC38987.1.
AK089207 mRNA. Translation: BAC40793.1.
CCDSiCCDS16762.1.
RefSeqiNP_848722.1. NM_178607.4.
UniGeneiMm.477523.

Genome annotation databases

EnsembliENSMUST00000059372; ENSMUSP00000058630; ENSMUSG00000048911.
ENSMUST00000110194; ENSMUSP00000105823; ENSMUSG00000048911.
ENSMUST00000165420; ENSMUSP00000129843; ENSMUSG00000048911.
GeneIDi51902.
KEGGimmu:51902.
UCSCiuc008mlk.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiRNF24_MOUSE
AccessioniPrimary (citable) accession number: Q8BGI1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: March 1, 2003
Last modified: August 30, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot