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Q8BGI1 (RNF24_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RING finger protein 24
Gene names
Name:Rnf24
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length148 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May play a role in TRPCs intracellular trafficking By similarity.

Subunit structure

Interacts with TRPC1, TRPC3, TRPC4, TRPC5, TRPC6 and TRPC7 By similarity.

Subcellular location

Golgi apparatus membrane; Single-pass membrane protein By similarity.

Sequence similarities

Contains 1 RING-type zinc finger.

Ontologies

Keywords
   Cellular componentGolgi apparatus
Membrane
   DomainTransmembrane
Transmembrane helix
Zinc-finger
   LigandMetal-binding
Zinc
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentGolgi membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

integral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionzinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 148148RING finger protein 24
PRO_0000056064

Regions

Transmembrane24 – 4421Helical; Potential
Zinc finger78 – 11942RING-type

Sequences

Sequence LengthMass (Da)Tools
Q8BGI1 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 96DFD3E31B6CC5C8

FASTA14817,254
        10         20         30         40         50         60 
MSSDFPHYNF RMPNIGFQNL PLNIYIVVFG TAVFVFILSL LFCCYLIRLR HQAHKEFYAY 

        70         80         90        100        110        120 
KQVILKEKVK ELNLHELCAV CLEDFKPRDE LGICPCKHAF HRKCLVKWLE VRKVCPLCNM 

       130        140 
PVLQLAQLHS KQDRGPPQEP LPGAENIV 

« Hide

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J and NOD.
Tissue: Cerebellum and Embryo.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK048813 mRNA. Translation: BAC33467.1.
AK083665 mRNA. Translation: BAC38987.1.
AK089207 mRNA. Translation: BAC40793.1.
RefSeqNP_848722.1. NM_178607.4.
XP_006499956.1. XM_006499893.1.
UniGeneMm.477523.

3D structure databases

ProteinModelPortalQ8BGI1.
SMRQ8BGI1. Positions 68-128.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ8BGI1.

Proteomic databases

PRIDEQ8BGI1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000059372; ENSMUSP00000058630; ENSMUSG00000048911.
ENSMUST00000110194; ENSMUSP00000105823; ENSMUSG00000048911.
ENSMUST00000165420; ENSMUSP00000129843; ENSMUSG00000048911.
GeneID51902.
KEGGmmu:51902.
UCSCuc008mlk.1. mouse.

Organism-specific databases

CTD11237.
MGIMGI:1261771. Rnf24.

Phylogenomic databases

eggNOGNOG299260.
GeneTreeENSGT00710000106755.
HOGENOMHOG000004806.
HOVERGENHBG058899.
InParanoidQ8BGI1.
OMAKQVIQKE.
OrthoDBEOG7XDBHK.
PhylomeDBQ8BGI1.

Gene expression databases

ArrayExpressQ8BGI1.
BgeeQ8BGI1.
CleanExMM_RNF24.
GenevestigatorQ8BGI1.

Family and domain databases

Gene3D3.30.40.10. 1 hit.
InterProIPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamPF13639. zf-RING_2. 1 hit.
[Graphical view]
SMARTSM00184. RING. 1 hit.
[Graphical view]
PROSITEPS50089. ZF_RING_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio308218.
PROQ8BGI1.
SOURCESearch...

Entry information

Entry nameRNF24_MOUSE
AccessionPrimary (citable) accession number: Q8BGI1
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: March 1, 2003
Last modified: April 16, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot