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Protein

Solute carrier family 25 member 44

Gene

Slc25a44

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 25 member 44
Gene namesi
Name:Slc25a44
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:2444391. Slc25a44.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei20 – 4223Helical; Name=1Sequence analysisAdd
BLAST
Transmembranei71 – 9020Helical; Name=2Sequence analysisAdd
BLAST
Transmembranei113 – 13321Helical; Name=3Sequence analysisAdd
BLAST
Transmembranei185 – 20117Helical; Name=4Sequence analysisAdd
BLAST
Transmembranei222 – 23918Helical; Name=5Sequence analysisAdd
BLAST
Transmembranei278 – 29619Helical; Name=6Sequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • mitochondrial inner membrane Source: UniProtKB-SubCell
  • mitochondrion Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 314314Solute carrier family 25 member 44PRO_0000253065Add
BLAST

Proteomic databases

MaxQBiQ8BGF9.
PaxDbiQ8BGF9.
PRIDEiQ8BGF9.

PTM databases

iPTMnetiQ8BGF9.
PhosphoSiteiQ8BGF9.

Expressioni

Gene expression databases

BgeeiQ8BGF9.
CleanExiMM_SLC25A44.
ExpressionAtlasiQ8BGF9. baseline and differential.
GenevisibleiQ8BGF9. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000057871.

Structurei

3D structure databases

ProteinModelPortaliQ8BGF9.
SMRiQ8BGF9. Positions 18-309.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati18 – 10083Solcar 1Add
BLAST
Repeati107 – 210104Solcar 2Add
BLAST
Repeati220 – 30283Solcar 3Add
BLAST

Sequence similaritiesi

Contains 3 Solcar repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0765. Eukaryota.
ENOG410XTGQ. LUCA.
GeneTreeiENSGT00530000062944.
HOVERGENiHBG054957.
InParanoidiQ8BGF9.
KOiK15121.
PhylomeDBiQ8BGF9.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BGF9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDKRNIQII EWEHLDKKKF YVFGVAMTMM IRVSVYPFTL IRTRLQVQKG
60 70 80 90 100
KSLYHGTFDA FVKILRADGV AGLYRGFLVN TFTLISGQCY VTTYELTRKF
110 120 130 140 150
VADYSQSNTV KSLVAGGSAS LVAQSITVPI DVVSQHLMMQ RKGEKMGRFQ
160 170 180 190 200
VHGNLEGQGV IAFGQTKDII RQILRADGLR GFYRGYVASL LTYIPNSAVW
210 220 230 240 250
WPFYHFYAEQ LSRLCPQECP HIVFQAISGP LAAATASILT NPMDVIRTRV
260 270 280 290 300
QVEGKSSIVL TFRQLMAEEG PWGLMKGLSA RIISATPSTI VIVVGYESLK
310
KLSLRPELVD SRHW
Length:314
Mass (Da):35,339
Last modified:March 1, 2003 - v1
Checksum:i9CA4C54D7C23A2AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK032960 mRNA. Translation: BAC28100.1.
AK046586 mRNA. Translation: BAC32798.1.
AK083273 mRNA. Translation: BAC38838.1.
AK083470 mRNA. Translation: BAC38927.1.
BC052771 mRNA. Translation: AAH52771.2.
CCDSiCCDS79943.1.
RefSeqiNP_001139348.1. NM_001145876.2.
NP_001139349.1. NM_001145877.2.
NP_001268724.1. NM_001281795.1.
UniGeneiMm.301740.

Genome annotation databases

EnsembliENSMUST00000193433; ENSMUSP00000141465; ENSMUSG00000050144.
ENSMUST00000195657; ENSMUSP00000141780; ENSMUSG00000050144.
GeneIDi229517.
KEGGimmu:229517.
UCSCiuc008pvc.3. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK032960 mRNA. Translation: BAC28100.1.
AK046586 mRNA. Translation: BAC32798.1.
AK083273 mRNA. Translation: BAC38838.1.
AK083470 mRNA. Translation: BAC38927.1.
BC052771 mRNA. Translation: AAH52771.2.
CCDSiCCDS79943.1.
RefSeqiNP_001139348.1. NM_001145876.2.
NP_001139349.1. NM_001145877.2.
NP_001268724.1. NM_001281795.1.
UniGeneiMm.301740.

3D structure databases

ProteinModelPortaliQ8BGF9.
SMRiQ8BGF9. Positions 18-309.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000057871.

PTM databases

iPTMnetiQ8BGF9.
PhosphoSiteiQ8BGF9.

Proteomic databases

MaxQBiQ8BGF9.
PaxDbiQ8BGF9.
PRIDEiQ8BGF9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000193433; ENSMUSP00000141465; ENSMUSG00000050144.
ENSMUST00000195657; ENSMUSP00000141780; ENSMUSG00000050144.
GeneIDi229517.
KEGGimmu:229517.
UCSCiuc008pvc.3. mouse.

Organism-specific databases

CTDi9673.
MGIiMGI:2444391. Slc25a44.

Phylogenomic databases

eggNOGiKOG0765. Eukaryota.
ENOG410XTGQ. LUCA.
GeneTreeiENSGT00530000062944.
HOVERGENiHBG054957.
InParanoidiQ8BGF9.
KOiK15121.
PhylomeDBiQ8BGF9.

Miscellaneous databases

ChiTaRSiSlc25a44. mouse.
PROiQ8BGF9.
SOURCEiSearch...

Gene expression databases

BgeeiQ8BGF9.
CleanExiMM_SLC25A44.
ExpressionAtlasiQ8BGF9. baseline and differential.
GenevisibleiQ8BGF9. MM.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Adipose tissue, Hippocampus and Wolffian duct.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Olfactory epithelium.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Brown adipose tissue.

Entry informationi

Entry nameiS2544_MOUSE
AccessioniPrimary (citable) accession number: Q8BGF9
Secondary accession number(s): Q7TSU9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: March 1, 2003
Last modified: July 6, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.