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Protein

Lipoma HMGIC fusion partner-like 2 protein

Gene

Lhfpl2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

ReactomeiR-MMU-114608. Platelet degranulation.

Protein family/group databases

TCDBi1.A.82.1.2. the hair cell mechanotransduction channel (hcmc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipoma HMGIC fusion partner-like 2 protein
Gene namesi
Name:Lhfpl2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:2145236. Lhfpl2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei11 – 31HelicalSequence analysisAdd BLAST21
Transmembranei97 – 117HelicalSequence analysisAdd BLAST21
Transmembranei127 – 147HelicalSequence analysisAdd BLAST21
Transmembranei175 – 195HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002447641 – 222Lipoma HMGIC fusion partner-like 2 proteinAdd BLAST222

Proteomic databases

PaxDbiQ8BGA2.
PRIDEiQ8BGA2.

PTM databases

PhosphoSitePlusiQ8BGA2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000045312.
CleanExiMM_LHFPL2.
ExpressionAtlasiQ8BGA2. baseline and differential.
GenevisibleiQ8BGA2. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000062239.

Structurei

3D structure databases

ProteinModelPortaliQ8BGA2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LHFP family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4026. Eukaryota.
ENOG410XSUB. LUCA.
GeneTreeiENSGT00550000074479.
HOGENOMiHOG000285972.
HOVERGENiHBG054430.
InParanoidiQ8BGA2.
OMAiVYPGEWK.
OrthoDBiEOG091G0J9C.
PhylomeDBiQ8BGA2.
TreeFamiTF321143.

Family and domain databases

InterProiIPR019372. Lipome_HGMIC_fus_partner-like.
[Graphical view]
PfamiPF10242. L_HMGIC_fpl. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BGA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCHVIVTCRS MLWTLLSIVV AFAELVAFMS ADWLIGKAKT RSGSGDEQAG
60 70 80 90 100
MNSEPHYLGI LCIRTPAMQQ VSRDTLCGTY AKSFGEIASG FWQATAIFLA
110 120 130 140 150
VGIFILCVVA LVSVFTMCVQ SIMRKSIFNV CGLLQGIAGL FLILGLILYP
160 170 180 190 200
AGWGCQKAID CGRYASPYKP GDCSLGWAFY TATGGTVLTF ICAVFSAQAE
210 220
IATSSDKVQE EIEEGKNLVC LL
Length:222
Mass (Da):23,873
Last modified:March 1, 2003 - v1
Checksum:iB105BF041868F1A9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC040389 mRNA. Translation: AAH40389.1.
AK030103 mRNA. Translation: BAC26786.1.
AK052969 mRNA. Translation: BAC35225.1.
AK087506 mRNA. Translation: BAC39903.1.
CCDSiCCDS26692.1.
RefSeqiNP_766177.1. NM_172589.2.
XP_011242941.1. XM_011244639.2.
XP_011242942.1. XM_011244640.1.
XP_011242943.1. XM_011244641.2.
XP_011242944.1. XM_011244642.2.
XP_011242945.1. XM_011244643.2.
XP_011242946.1. XM_011244644.2.
UniGeneiMm.316553.

Genome annotation databases

EnsembliENSMUST00000054274; ENSMUSP00000062239; ENSMUSG00000045312.
ENSMUST00000118195; ENSMUSP00000112655; ENSMUSG00000045312.
ENSMUST00000121618; ENSMUSP00000113468; ENSMUSG00000045312.
GeneIDi218454.
KEGGimmu:218454.
UCSCiuc007rlp.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC040389 mRNA. Translation: AAH40389.1.
AK030103 mRNA. Translation: BAC26786.1.
AK052969 mRNA. Translation: BAC35225.1.
AK087506 mRNA. Translation: BAC39903.1.
CCDSiCCDS26692.1.
RefSeqiNP_766177.1. NM_172589.2.
XP_011242941.1. XM_011244639.2.
XP_011242942.1. XM_011244640.1.
XP_011242943.1. XM_011244641.2.
XP_011242944.1. XM_011244642.2.
XP_011242945.1. XM_011244643.2.
XP_011242946.1. XM_011244644.2.
UniGeneiMm.316553.

3D structure databases

ProteinModelPortaliQ8BGA2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000062239.

Protein family/group databases

TCDBi1.A.82.1.2. the hair cell mechanotransduction channel (hcmc) family.

PTM databases

PhosphoSitePlusiQ8BGA2.

Proteomic databases

PaxDbiQ8BGA2.
PRIDEiQ8BGA2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000054274; ENSMUSP00000062239; ENSMUSG00000045312.
ENSMUST00000118195; ENSMUSP00000112655; ENSMUSG00000045312.
ENSMUST00000121618; ENSMUSP00000113468; ENSMUSG00000045312.
GeneIDi218454.
KEGGimmu:218454.
UCSCiuc007rlp.1. mouse.

Organism-specific databases

CTDi10184.
MGIiMGI:2145236. Lhfpl2.

Phylogenomic databases

eggNOGiKOG4026. Eukaryota.
ENOG410XSUB. LUCA.
GeneTreeiENSGT00550000074479.
HOGENOMiHOG000285972.
HOVERGENiHBG054430.
InParanoidiQ8BGA2.
OMAiVYPGEWK.
OrthoDBiEOG091G0J9C.
PhylomeDBiQ8BGA2.
TreeFamiTF321143.

Enzyme and pathway databases

ReactomeiR-MMU-114608. Platelet degranulation.

Miscellaneous databases

PROiQ8BGA2.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000045312.
CleanExiMM_LHFPL2.
ExpressionAtlasiQ8BGA2. baseline and differential.
GenevisibleiQ8BGA2. MM.

Family and domain databases

InterProiIPR019372. Lipome_HGMIC_fus_partner-like.
[Graphical view]
PfamiPF10242. L_HMGIC_fpl. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLHPL2_MOUSE
AccessioniPrimary (citable) accession number: Q8BGA2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: March 1, 2003
Last modified: November 2, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.