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Protein

AN1-type zinc finger protein 1

Gene

Zfand1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri7 – 5448AN1-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri61 – 10747AN1-type 2PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
AN1-type zinc finger protein 1
Gene namesi
Name:Zfand1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1913611. Zfand1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 268268AN1-type zinc finger protein 1PRO_0000066581Add
BLAST

Proteomic databases

EPDiQ8BFR6.
MaxQBiQ8BFR6.
PaxDbiQ8BFR6.
PRIDEiQ8BFR6.

PTM databases

PhosphoSiteiQ8BFR6.

Expressioni

Gene expression databases

BgeeiENSMUSG00000039795.
CleanExiMM_ZFAND1.
ExpressionAtlasiQ8BFR6. baseline and differential.
GenevisibleiQ8BFR6. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000037459.

Structurei

Secondary structure

1
268
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Turni13 – 153Combined sources
Turni26 – 283Combined sources
Helixi40 – 423Combined sources
Beta strandi72 – 754Combined sources
Turni80 – 823Combined sources
Helixi88 – 903Combined sources
Helixi94 – 963Combined sources
Beta strandi99 – 1024Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1WFENMR-A44-116[»]
1WYSNMR-A1-62[»]
ProteinModelPortaliQ8BFR6.
SMRiQ8BFR6. Positions 1-116.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8BFR6.

Family & Domainsi

Sequence similaritiesi

Contains 2 AN1-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri7 – 5448AN1-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri61 – 10747AN1-type 2PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG3183. Eukaryota.
ENOG4111JCH. LUCA.
GeneTreeiENSGT00730000111180.
HOGENOMiHOG000007730.
HOVERGENiHBG061273.
InParanoidiQ8BFR6.
OMAiGQHCQVE.
OrthoDBiEOG091G0ASV.
PhylomeDBiQ8BFR6.
TreeFamiTF314219.

Family and domain databases

Gene3Di4.10.1110.10. 2 hits.
InterProiIPR000058. Znf_AN1.
[Graphical view]
PfamiPF01428. zf-AN1. 2 hits.
[Graphical view]
SMARTiSM00154. ZnF_AN1. 2 hits.
[Graphical view]
PROSITEiPS51039. ZF_AN1. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BFR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAELDIGQHC QVQHCRQRDF LPFVCDGCSG IFCLEHRSKD SHGCSEVNVV
60 70 80 90 100
KERPKTDEHK SYSCSFKGCT DVELVAVICP YCEKNFCLRH RHQSDHDCEK
110 120 130 140 150
LEVAKPRMAA TQKLVRDIVD AKTGGAASKG RKGAKSSGTA AKVALMKLKM
160 170 180 190 200
HADGDKSLPQ TERTYFQVYL PKGSKEKSKA MFFCLRWSIG KVVDFAASLA
210 220 230 240 250
NLRNENNKLT AKKLRLCHVP SGEALPLDHT LERWITKEEC PLYNGGNVIL
260
EYLNDEEQFL KNVDSYLE
Length:268
Mass (Da):30,203
Last modified:March 1, 2003 - v1
Checksum:iF852DD01553EBAC0
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti102 – 1021E → V in BAB26161 (PubMed:16141072).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK009240 mRNA. Translation: BAB26161.1.
AK030472 mRNA. Translation: BAC26977.1.
AK077873 mRNA. Translation: BAC37044.1.
BC023352 mRNA. Translation: AAH23352.1.
BC046585 mRNA. Translation: AAH46585.1.
BC089494 mRNA. Translation: AAH89494.1.
CCDSiCCDS17242.1.
RefSeqiNP_079788.2. NM_025512.2.
UniGeneiMm.371617.

Genome annotation databases

EnsembliENSMUST00000037839; ENSMUSP00000037459; ENSMUSG00000039795.
GeneIDi66361.
KEGGimmu:66361.
UCSCiuc008ops.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK009240 mRNA. Translation: BAB26161.1.
AK030472 mRNA. Translation: BAC26977.1.
AK077873 mRNA. Translation: BAC37044.1.
BC023352 mRNA. Translation: AAH23352.1.
BC046585 mRNA. Translation: AAH46585.1.
BC089494 mRNA. Translation: AAH89494.1.
CCDSiCCDS17242.1.
RefSeqiNP_079788.2. NM_025512.2.
UniGeneiMm.371617.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1WFENMR-A44-116[»]
1WYSNMR-A1-62[»]
ProteinModelPortaliQ8BFR6.
SMRiQ8BFR6. Positions 1-116.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000037459.

PTM databases

PhosphoSiteiQ8BFR6.

Proteomic databases

EPDiQ8BFR6.
MaxQBiQ8BFR6.
PaxDbiQ8BFR6.
PRIDEiQ8BFR6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000037839; ENSMUSP00000037459; ENSMUSG00000039795.
GeneIDi66361.
KEGGimmu:66361.
UCSCiuc008ops.1. mouse.

Organism-specific databases

CTDi79752.
MGIiMGI:1913611. Zfand1.

Phylogenomic databases

eggNOGiKOG3183. Eukaryota.
ENOG4111JCH. LUCA.
GeneTreeiENSGT00730000111180.
HOGENOMiHOG000007730.
HOVERGENiHBG061273.
InParanoidiQ8BFR6.
OMAiGQHCQVE.
OrthoDBiEOG091G0ASV.
PhylomeDBiQ8BFR6.
TreeFamiTF314219.

Miscellaneous databases

EvolutionaryTraceiQ8BFR6.
PROiQ8BFR6.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000039795.
CleanExiMM_ZFAND1.
ExpressionAtlasiQ8BFR6. baseline and differential.
GenevisibleiQ8BFR6. MM.

Family and domain databases

Gene3Di4.10.1110.10. 2 hits.
InterProiIPR000058. Znf_AN1.
[Graphical view]
PfamiPF01428. zf-AN1. 2 hits.
[Graphical view]
SMARTiSM00154. ZnF_AN1. 2 hits.
[Graphical view]
PROSITEiPS51039. ZF_AN1. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiZFAN1_MOUSE
AccessioniPrimary (citable) accession number: Q8BFR6
Secondary accession number(s): Q8R3Y6, Q9D7H5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: March 1, 2003
Last modified: September 7, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.