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Protein
Submitted name:

Prosaposin

Gene

Psap

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ProsaposinImported
Submitted name:
Prosaposin, isoform CRA_aImported
Submitted name:
Psap proteinImported
Gene namesi
Name:PsapImported
ORF Names:mCG_61290Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:97783. Psap.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_500878419817 – 554Sequence analysisAdd BLAST538

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi63 ↔ 138UniRule annotation
Disulfide bondi66 ↔ 132UniRule annotation
Disulfide bondi94 ↔ 106UniRule annotation
Disulfide bondi197 ↔ 270UniRule annotation
Disulfide bondi200 ↔ 264UniRule annotation
Disulfide bondi229 ↔ 240UniRule annotation
Disulfide bondi314 ↔ 387UniRule annotation
Disulfide bondi317 ↔ 381UniRule annotation
Disulfide bondi345 ↔ 356UniRule annotation
Disulfide bondi439 ↔ 512UniRule annotation
Disulfide bondi442 ↔ 506UniRule annotation
Disulfide bondi470 ↔ 481UniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000004207.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000137476.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 58Saposin A-typeInterPro annotationAdd BLAST41
Domaini59 – 142Saposin B-typeInterPro annotationAdd BLAST84
Domaini193 – 274Saposin B-typeInterPro annotationAdd BLAST82
Domaini310 – 391Saposin B-typeInterPro annotationAdd BLAST82
Domaini435 – 516Saposin B-typeInterPro annotationAdd BLAST82
Domaini518 – 554Saposin A-typeInterPro annotationAdd BLAST37

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1340. Eukaryota.
ENOG410XSI5. LUCA.
GeneTreeiENSGT00530000063434.
HOVERGENiHBG002617.
TreeFamiTF316942.

Family and domain databases

Gene3Di1.10.225.10. 4 hits.
InterProiIPR003119. SAP_A.
IPR007856. SapB_1.
IPR008138. SapB_2.
IPR008373. Saposin.
IPR011001. Saposin-like.
IPR021165. Saposin_chordata.
IPR008139. SaposinB_dom.
[Graphical view]
PfamiPF02199. SapA. 2 hits.
PF05184. SapB_1. 4 hits.
PF03489. SapB_2. 4 hits.
[Graphical view]
PIRSFiPIRSF002431. Saposin. 1 hit.
PRINTSiPR01797. SAPOSIN.
SMARTiSM00162. SAPA. 2 hits.
SM00741. SapB. 4 hits.
[Graphical view]
SUPFAMiSSF47862. SSF47862. 3 hits.
PROSITEiPS51110. SAP_A. 2 hits.
PS50015. SAP_B. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8BFQ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYALALFASL LATALTSPVQ DPKTCSGGSA VLCRDVKTAV DCGAVKHCQQ
60 70 80 90 100
MVWSKPTAKS LPCDICKTVV TEAGNLLKDN ATQEEILHYL EKTCEWIHDS
110 120 130 140 150
SLSASCKEVV DSYLPVILDM IKGEMSNPGE VCSALNLCQS LQEYLAEQNQ
160 170 180 190 200
KQLESNKIPE VDMARVVAPF MSNIPLLLYP QDHPRSQPQP KANEDVCQDC
210 220 230 240 250
MKLVSDVQTA VKTNSSFIQG FVDHVKEDCD RLGPGVSDIC KNYVDQYSEV
260 270 280 290 300
CVQMLMHMQP KEICVLAGFC NEVKRVPMKT LVPATETIKN ILPALEMMDP
310 320 330 340 350
YEQNLVQAHN VILCQTCQFV MNKFSELIVN NATEELLVKG LSNACALLPD
360 370 380 390 400
PARTKCQEVV GTFGPSLLDI FIHEVNPSSL CGVIGLCAAR PELVEALEQP
410 420 430 440 450
APAIVSALLK EPTPPKQPAQ PKQSALPAHV PPQKNGGFCE VCKKLVLYLE
460 470 480 490 500
HNLEKNSTKE EILAALEKGC SFLPDPYQKQ CDDFVAEYEP LLLEILVEVM
510 520 530 540 550
DPGFVCSKIG VCPSAYKLLL GTEKCVWGPS YWCQNMETAA RCNAVDHCKR

HVWN
Length:554
Mass (Da):61,051
Last modified:March 1, 2003 - v1
Checksum:iFF58DB79C7CC0C18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079082 Genomic DNA. No translation available.
BC145359 mRNA. Translation: AAI45360.1.
AK088369 mRNA. Translation: BAC40308.1.
AK089998 mRNA. Translation: BAC41035.1.
AK135637 mRNA. Translation: BAE22597.1.
AK145802 mRNA. Translation: BAE26658.1.
AK148152 mRNA. Translation: BAE28378.1.
AK150331 mRNA. Translation: BAE29473.1.
AK151034 mRNA. Translation: BAE30051.1.
AK151173 mRNA. Translation: BAE30176.1.
AK151230 mRNA. Translation: BAE30222.1.
AK151525 mRNA. Translation: BAE30473.1.
AK151686 mRNA. Translation: BAE30610.1.
AK151852 mRNA. Translation: BAE30742.1.
AK151891 mRNA. Translation: BAE30775.1.
AK151907 mRNA. Translation: BAE30788.1.
AK151943 mRNA. Translation: BAE30819.1.
AK152117 mRNA. Translation: BAE30961.1.
AK152126 mRNA. Translation: BAE30967.1.
AK152134 mRNA. Translation: BAE30975.1.
AK152203 mRNA. Translation: BAE31032.1.
AK152355 mRNA. Translation: BAE31147.1.
AK152505 mRNA. Translation: BAE31272.1.
AK152557 mRNA. Translation: BAE31311.1.
AK152605 mRNA. Translation: BAE31352.1.
AK152819 mRNA. Translation: BAE31522.1.
AK159108 mRNA. Translation: BAE34824.1.
AK159198 mRNA. Translation: BAE34893.1.
AK159266 mRNA. Translation: BAE34946.1.
AK159333 mRNA. Translation: BAE34998.1.
AK159341 mRNA. Translation: BAE35003.1.
AK159384 mRNA. Translation: BAE35039.1.
AK159427 mRNA. Translation: BAE35074.1.
AK159451 mRNA. Translation: BAE35094.1.
AK159457 mRNA. Translation: BAE35099.1.
AK159463 mRNA. Translation: BAE35104.1.
AK159487 mRNA. Translation: BAE35122.1.
AK159510 mRNA. Translation: BAE35142.1.
AK159528 mRNA. Translation: BAE35157.1.
AK159530 mRNA. Translation: BAE35159.1.
AK159589 mRNA. Translation: BAE35209.1.
AK159604 mRNA. Translation: BAE35223.1.
AK159657 mRNA. Translation: BAE35266.1.
AK159685 mRNA. Translation: BAE35288.1.
AK159720 mRNA. Translation: BAE35315.1.
AK159728 mRNA. Translation: BAE35322.1.
AK159840 mRNA. Translation: BAE35418.1.
AK159861 mRNA. Translation: BAE35435.1.
AK159862 mRNA. Translation: BAE35436.1.
AK159877 mRNA. Translation: BAE35449.1.
AK159910 mRNA. Translation: BAE35473.1.
AK159915 mRNA. Translation: BAE35478.1.
AK159936 mRNA. Translation: BAE35496.1.
AK159982 mRNA. Translation: BAE35533.1.
AK159994 mRNA. Translation: BAE35544.1.
AK160015 mRNA. Translation: BAE35561.1.
AK160024 mRNA. Translation: BAE35567.1.
AK160046 mRNA. Translation: BAE35588.1.
AK160877 mRNA. Translation: BAE36065.1.
AK161313 mRNA. Translation: BAE36317.1.
AK166700 mRNA. Translation: BAE38955.1.
AK166707 mRNA. Translation: BAE38961.1.
AK166744 mRNA. Translation: BAE38986.1.
AK166811 mRNA. Translation: BAE39038.1.
AK166849 mRNA. Translation: BAE39068.1.
AK166879 mRNA. Translation: BAE39090.1.
AK166909 mRNA. Translation: BAE39110.1.
AK166920 mRNA. Translation: BAE39117.1.
AK167014 mRNA. Translation: BAE39190.1.
AK167025 mRNA. Translation: BAE39198.1.
AK167111 mRNA. Translation: BAE39259.1.
AK167237 mRNA. Translation: BAE39359.1.
AK167418 mRNA. Translation: BAE39506.1.
AK170416 mRNA. Translation: BAE41782.1.
CH466553 Genomic DNA. Translation: EDL32174.1.
RefSeqiNP_001139592.1. NM_001146120.1.
UniGeneiMm.277498.
Mm.29978.

Genome annotation databases

EnsembliENSMUST00000105465; ENSMUSP00000101105; ENSMUSG00000004207.
GeneIDi19156.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079082 Genomic DNA. No translation available.
BC145359 mRNA. Translation: AAI45360.1.
AK088369 mRNA. Translation: BAC40308.1.
AK089998 mRNA. Translation: BAC41035.1.
AK135637 mRNA. Translation: BAE22597.1.
AK145802 mRNA. Translation: BAE26658.1.
AK148152 mRNA. Translation: BAE28378.1.
AK150331 mRNA. Translation: BAE29473.1.
AK151034 mRNA. Translation: BAE30051.1.
AK151173 mRNA. Translation: BAE30176.1.
AK151230 mRNA. Translation: BAE30222.1.
AK151525 mRNA. Translation: BAE30473.1.
AK151686 mRNA. Translation: BAE30610.1.
AK151852 mRNA. Translation: BAE30742.1.
AK151891 mRNA. Translation: BAE30775.1.
AK151907 mRNA. Translation: BAE30788.1.
AK151943 mRNA. Translation: BAE30819.1.
AK152117 mRNA. Translation: BAE30961.1.
AK152126 mRNA. Translation: BAE30967.1.
AK152134 mRNA. Translation: BAE30975.1.
AK152203 mRNA. Translation: BAE31032.1.
AK152355 mRNA. Translation: BAE31147.1.
AK152505 mRNA. Translation: BAE31272.1.
AK152557 mRNA. Translation: BAE31311.1.
AK152605 mRNA. Translation: BAE31352.1.
AK152819 mRNA. Translation: BAE31522.1.
AK159108 mRNA. Translation: BAE34824.1.
AK159198 mRNA. Translation: BAE34893.1.
AK159266 mRNA. Translation: BAE34946.1.
AK159333 mRNA. Translation: BAE34998.1.
AK159341 mRNA. Translation: BAE35003.1.
AK159384 mRNA. Translation: BAE35039.1.
AK159427 mRNA. Translation: BAE35074.1.
AK159451 mRNA. Translation: BAE35094.1.
AK159457 mRNA. Translation: BAE35099.1.
AK159463 mRNA. Translation: BAE35104.1.
AK159487 mRNA. Translation: BAE35122.1.
AK159510 mRNA. Translation: BAE35142.1.
AK159528 mRNA. Translation: BAE35157.1.
AK159530 mRNA. Translation: BAE35159.1.
AK159589 mRNA. Translation: BAE35209.1.
AK159604 mRNA. Translation: BAE35223.1.
AK159657 mRNA. Translation: BAE35266.1.
AK159685 mRNA. Translation: BAE35288.1.
AK159720 mRNA. Translation: BAE35315.1.
AK159728 mRNA. Translation: BAE35322.1.
AK159840 mRNA. Translation: BAE35418.1.
AK159861 mRNA. Translation: BAE35435.1.
AK159862 mRNA. Translation: BAE35436.1.
AK159877 mRNA. Translation: BAE35449.1.
AK159910 mRNA. Translation: BAE35473.1.
AK159915 mRNA. Translation: BAE35478.1.
AK159936 mRNA. Translation: BAE35496.1.
AK159982 mRNA. Translation: BAE35533.1.
AK159994 mRNA. Translation: BAE35544.1.
AK160015 mRNA. Translation: BAE35561.1.
AK160024 mRNA. Translation: BAE35567.1.
AK160046 mRNA. Translation: BAE35588.1.
AK160877 mRNA. Translation: BAE36065.1.
AK161313 mRNA. Translation: BAE36317.1.
AK166700 mRNA. Translation: BAE38955.1.
AK166707 mRNA. Translation: BAE38961.1.
AK166744 mRNA. Translation: BAE38986.1.
AK166811 mRNA. Translation: BAE39038.1.
AK166849 mRNA. Translation: BAE39068.1.
AK166879 mRNA. Translation: BAE39090.1.
AK166909 mRNA. Translation: BAE39110.1.
AK166920 mRNA. Translation: BAE39117.1.
AK167014 mRNA. Translation: BAE39190.1.
AK167025 mRNA. Translation: BAE39198.1.
AK167111 mRNA. Translation: BAE39259.1.
AK167237 mRNA. Translation: BAE39359.1.
AK167418 mRNA. Translation: BAE39506.1.
AK170416 mRNA. Translation: BAE41782.1.
CH466553 Genomic DNA. Translation: EDL32174.1.
RefSeqiNP_001139592.1. NM_001146120.1.
UniGeneiMm.277498.
Mm.29978.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000137476.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000105465; ENSMUSP00000101105; ENSMUSG00000004207.
GeneIDi19156.

Organism-specific databases

CTDi5660.
MGIiMGI:97783. Psap.

Phylogenomic databases

eggNOGiKOG1340. Eukaryota.
ENOG410XSI5. LUCA.
GeneTreeiENSGT00530000063434.
HOVERGENiHBG002617.
TreeFamiTF316942.

Miscellaneous databases

ChiTaRSiPsap. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000004207.

Family and domain databases

Gene3Di1.10.225.10. 4 hits.
InterProiIPR003119. SAP_A.
IPR007856. SapB_1.
IPR008138. SapB_2.
IPR008373. Saposin.
IPR011001. Saposin-like.
IPR021165. Saposin_chordata.
IPR008139. SaposinB_dom.
[Graphical view]
PfamiPF02199. SapA. 2 hits.
PF05184. SapB_1. 4 hits.
PF03489. SapB_2. 4 hits.
[Graphical view]
PIRSFiPIRSF002431. Saposin. 1 hit.
PRINTSiPR01797. SAPOSIN.
SMARTiSM00162. SAPA. 2 hits.
SM00741. SapB. 4 hits.
[Graphical view]
SUPFAMiSSF47862. SSF47862. 3 hits.
PROSITEiPS51110. SAP_A. 2 hits.
PS50015. SAP_B. 4 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8BFQ1_MOUSE
AccessioniPrimary (citable) accession number: Q8BFQ1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: November 30, 2016
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.