Q8B3C1 (Q8B3C1_9INFA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Neuraminidase EMBL CAD35677.1
Organism	Influenza A virus (A/1496/02(H1N2)) EMBL CAD35677.1
Taxonomic identifier	198578 [NCBI]
Taxonomic lineage	Viruses › ssRNA negative-strand viruses › Orthomyxoviridae › Influenzavirus A

Protein attributes

Sequence length	469 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. SAAS SAAS011040
Subunit structure	Homotetramer By similarity. SAAS SAAS011040

Ontologies

Keywords
Cellular component	Host cell membrane SAAS SAAS011040 Host membrane Membrane Virion SAAS SAAS011040
Domain	Transmembrane Transmembrane helix SAAS SAAS011040
Molecular function	Glycosidase SAAS SAAS011040 Hydrolase
PTM	Disulfide bond SAAS SAAS011040
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	host cell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW virion Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	exo-alpha-sialidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL CAD35677.1
	Non-terminal residue	469	1	EMBL CAD35677.1

Sequences

	Sequence		Length	Mass (Da)
	Q8B3C1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: E4E37BF59F58335A	FASTA	469	51,826
	10 20 30 40 50 60 MNPNQKIITI GSVSLTIATI CFLTQIAILV TTVTLHFKQY ECNSPPNNQV MLCEPTIIER 70 80 90 100 110 120 NITEIVYLTN TTIEKEICPK LAEYRNWSKP QCNITGFAPF SKDNSIRLSA GGDIWVTREP 130 140 150 160 170 180 YVSCDPDKCY QFALGQGTTL NNGHSNDTVH DRTPYRTLLM NELGVPFHLG TKQVCIAWSS 190 200 210 220 230 240 SSCHDGKAWL HVCVTGDDKN ATASFIYNGR LVDSIGSWSK KILRTQESEC VCINGTCTVV 250 260 270 280 290 300 MTDGSASGKA DTKILFIEEG KIVHTSLLSG SAQHVEECSC YPRYPGVRCV CRDNWKGSNR 310 320 330 340 350 360 PIVDINVKDY SIVSSYVCSG LVGDTPRKND SSSSSHCLDP NNEEGGHGVK GWAFDDGNDV 370 380 390 400 410 420 WMGRTISEKL RSGYETFKVI EGWSKPNSKL QINRQVIVDR GNRSGYSGIF SVEGKSCINR 430 440 450 460 CFYVELIRGR NQETEVLWTS NSIVVFCGTS GTYGTGSWPD GADINLMPI

References

[1]	"Influenza AH1N2 viruses, United Kingdom, 2001-02 influenza season." Ellis J.S., Alvarez-Aguero A., Gregory V., Lin Y.P., Hay A., Zambon M.C. Emerg. Infect. Dis. 9:304-310(2003) [PubMed: 12643824] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: A/1496/02 EMBL CAD35677.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ489851 Genomic RNA. Translation: CAD35677.1.
3D structure databases
HSSP	HSSP built from PDB template 1IVF based on UniProtKB P06820.
ProteinModelPortal	Q8B3C1.
ModBase	Search...
Protein family/group databases
CAZy	GH34. Glycoside Hydrolase Family 34.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR001860. Glyco_hydro_34. IPR011040. Neuraminidase. [Graphical view]
Gene3D	G3DSA:2.120.10.10. Neuraminidase. 1 hit.
Pfam	PF00064. Neur. 1 hit. [Graphical view]
SUPFAM	SSF50939. Sialidase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8B3C1_9INFA

Accession

Primary (citable) accession number: Q8B3C1

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)