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Q8AYP8

- Q8AYP8_CHICK

UniProt

Q8AYP8 - Q8AYP8_CHICK

Protein
Submitted name:

Hexokinase1

Gene

HK1

Organism
Gallus gallus (Chicken)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. hexokinase activity Source: InterPro

    GO - Biological processi

    1. carbohydrate metabolic process Source: Reactome
    2. glucose transport Source: Reactome
    3. glycolytic process Source: UniProtKB-KW
    4. small molecule metabolic process Source: Reactome

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    GlycolysisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    ReactomeiREACT_115616. Glucose transport.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Hexokinase1Imported
    Gene namesi
    Name:HK1Imported
    OrganismiGallus gallus (Chicken)Imported
    Taxonomic identifieri9031 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: Reactome

    Structurei

    3D structure databases

    ProteinModelPortaliQ8AYP8.
    SMRiQ8AYP8. Positions 16-912.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the hexokinase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000162671.
    HOVERGENiHBG005020.
    InParanoidiQ8AYP8.
    KOiK00844.
    PhylomeDBiQ8AYP8.

    Family and domain databases

    InterProiIPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR019807. Hexokinase_CS.
    IPR022672. Hexokinase_N.
    [Graphical view]
    PANTHERiPTHR19443. PTHR19443. 1 hit.
    PfamiPF00349. Hexokinase_1. 2 hits.
    PF03727. Hexokinase_2. 2 hits.
    [Graphical view]
    PRINTSiPR00475. HEXOKINASE.
    PROSITEiPS00378. HEXOKINASES. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8AYP8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIAAQLLAYY FTELKEDQVK KIDKYLYAMR LSDETLIDIM ARFRREMKNG    50
    LSRDFNPTAT VKMLPTFVRS IPDGSEKGDF IALDLGGSYF RILRVKVSHE 100
    KKQTVQMESE IYNTPEDIIH GSGTRLFDHV AECLGDFMEK QQIKDKKLPV 150
    GFTFSFPCRQ SKLDEGILIT WTKRFKASGV EGADVVKLLN KAIKKRGDYD 200
    ADIMAVVNDT VGTMMTCGFD DQRCEVGLII GTGTNACYME EMRHIDLVEG 250
    DEGRMCINTE WGAFGDDGSL EDIRTEFDRE IDRGSLNPGK QLFEKMVSGM 300
    YMGELVRLIL VKMAKEGLLF EGRITPELPT KGKFETKHVS AIEKSKEGLN 350
    KAKEILTRLG VEPSHEDCIA VQHVCTIVSF RSANLAASTL GAILNQLRDN 400
    KGVGRLRTTV GVDGSLYKMH PQYARRLHKT TRRLVPDSDV RFLLSESGSG 450
    KGAAMVTAVA YRLSEQHRLI DETLAEFKLT HEQLLQVKKR MRTEMEAGLK 500
    KKSHETAKVK MLPTFVRSTP DGTENGDFLA LDLGGTNFRV LLVKIRSGKR 550
    RTVEMHNKIY AIPIEVMQGT GEELFDHIVT CISDFLDYMG IRGARLPLGF 600
    TFSFPCKQTS LDAGILLNWT KGFKATDCEG EDVVYLLREG IKRREEFDLD 650
    VVAVVNDTVG TMMTCAYEDP NCEIGLIVGT GSNACYMEEM RNIEMVDGEQ 700
    GRMCVNMEWG AFGDNGCLDD IRTIYDKAVD DYSLNAGKQR YEKMISGMYL 750
    GEIVRNILID FTKRGFLFRG QISETLKTRH IFETKFLSQI ESDRLALLQV 800
    RTILQQLGLN STCDDSIIVK TVCGGVSKRA AQLCGAGMAA VVDKIRENRG 850
    LEHLEITVGV DGTLYKLHPH FSRIMHQTVK DLAPKCDVTF LLSEDGSGKG 900
    AALITAVGCR VRDAEQN 917
    Length:917
    Mass (Da):102,715
    Last modified:March 1, 2003 - v1
    Checksum:iFD6B22E0B93DEF18
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB083369 mRNA. Translation: BAC20932.1.
    RefSeqiNP_989432.1. NM_204101.1.
    UniGeneiGga.2197.

    Genome annotation databases

    GeneIDi373889.
    KEGGigga:373889.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB083369 mRNA. Translation: BAC20932.1 .
    RefSeqi NP_989432.1. NM_204101.1.
    UniGenei Gga.2197.

    3D structure databases

    ProteinModelPortali Q8AYP8.
    SMRi Q8AYP8. Positions 16-912.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 373889.
    KEGGi gga:373889.

    Organism-specific databases

    CTDi 3098.

    Phylogenomic databases

    HOGENOMi HOG000162671.
    HOVERGENi HBG005020.
    InParanoidi Q8AYP8.
    KOi K00844.
    PhylomeDBi Q8AYP8.

    Enzyme and pathway databases

    Reactomei REACT_115616. Glucose transport.

    Miscellaneous databases

    NextBioi 20813421.

    Family and domain databases

    InterProi IPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR019807. Hexokinase_CS.
    IPR022672. Hexokinase_N.
    [Graphical view ]
    PANTHERi PTHR19443. PTHR19443. 1 hit.
    Pfami PF00349. Hexokinase_1. 2 hits.
    PF03727. Hexokinase_2. 2 hits.
    [Graphical view ]
    PRINTSi PR00475. HEXOKINASE.
    PROSITEi PS00378. HEXOKINASES. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and gene expression of hexokinase I and II in the chicken skeletal muscle."
      Seki Y., Sato K., Kono T., Akiba Y.
      Anim. Sci. J. 76:491-497(2005)
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ8AYP8_CHICK
    AccessioniPrimary (citable) accession number: Q8AYP8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)