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Protein
Submitted name:

Hexokinase1

Gene

HK1

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotationImported, Transferase
Biological processGlycolysisSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-GGA-352832 Glucose transport

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase1Imported
Gene namesi
Name:HK1Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Structurei

3D structure databases

ProteinModelPortaliQ8AYP8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 219Hexokinase_1InterPro annotationAdd BLAST198
Domaini225 – 459Hexokinase_2InterPro annotationAdd BLAST235
Domaini470 – 667Hexokinase_1InterPro annotationAdd BLAST198
Domaini673 – 907Hexokinase_2InterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the hexokinase family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1369 Eukaryota
COG5026 LUCA
HOGENOMiHOG000162671
HOVERGENiHBG005020
KOiK00844
PhylomeDBiQ8AYP8

Family and domain databases

InterProiView protein in InterPro
IPR001312 Hexokinase
IPR019807 Hexokinase_BS
IPR022673 Hexokinase_C
IPR022672 Hexokinase_N
PANTHERiPTHR19443 PTHR19443, 4 hits
PfamiView protein in Pfam
PF00349 Hexokinase_1, 2 hits
PF03727 Hexokinase_2, 2 hits
PROSITEiView protein in PROSITE
PS00378 HEXOKINASE_1, 2 hits
PS51748 HEXOKINASE_2, 2 hits

Sequencei

Sequence statusi: Complete.

Q8AYP8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIAAQLLAYY FTELKEDQVK KIDKYLYAMR LSDETLIDIM ARFRREMKNG
60 70 80 90 100
LSRDFNPTAT VKMLPTFVRS IPDGSEKGDF IALDLGGSYF RILRVKVSHE
110 120 130 140 150
KKQTVQMESE IYNTPEDIIH GSGTRLFDHV AECLGDFMEK QQIKDKKLPV
160 170 180 190 200
GFTFSFPCRQ SKLDEGILIT WTKRFKASGV EGADVVKLLN KAIKKRGDYD
210 220 230 240 250
ADIMAVVNDT VGTMMTCGFD DQRCEVGLII GTGTNACYME EMRHIDLVEG
260 270 280 290 300
DEGRMCINTE WGAFGDDGSL EDIRTEFDRE IDRGSLNPGK QLFEKMVSGM
310 320 330 340 350
YMGELVRLIL VKMAKEGLLF EGRITPELPT KGKFETKHVS AIEKSKEGLN
360 370 380 390 400
KAKEILTRLG VEPSHEDCIA VQHVCTIVSF RSANLAASTL GAILNQLRDN
410 420 430 440 450
KGVGRLRTTV GVDGSLYKMH PQYARRLHKT TRRLVPDSDV RFLLSESGSG
460 470 480 490 500
KGAAMVTAVA YRLSEQHRLI DETLAEFKLT HEQLLQVKKR MRTEMEAGLK
510 520 530 540 550
KKSHETAKVK MLPTFVRSTP DGTENGDFLA LDLGGTNFRV LLVKIRSGKR
560 570 580 590 600
RTVEMHNKIY AIPIEVMQGT GEELFDHIVT CISDFLDYMG IRGARLPLGF
610 620 630 640 650
TFSFPCKQTS LDAGILLNWT KGFKATDCEG EDVVYLLREG IKRREEFDLD
660 670 680 690 700
VVAVVNDTVG TMMTCAYEDP NCEIGLIVGT GSNACYMEEM RNIEMVDGEQ
710 720 730 740 750
GRMCVNMEWG AFGDNGCLDD IRTIYDKAVD DYSLNAGKQR YEKMISGMYL
760 770 780 790 800
GEIVRNILID FTKRGFLFRG QISETLKTRH IFETKFLSQI ESDRLALLQV
810 820 830 840 850
RTILQQLGLN STCDDSIIVK TVCGGVSKRA AQLCGAGMAA VVDKIRENRG
860 870 880 890 900
LEHLEITVGV DGTLYKLHPH FSRIMHQTVK DLAPKCDVTF LLSEDGSGKG
910
AALITAVGCR VRDAEQN
Length:917
Mass (Da):102,715
Last modified:March 1, 2003 - v1
Checksum:iFD6B22E0B93DEF18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB083369 mRNA Translation: BAC20932.1
RefSeqiNP_989432.1, NM_204101.1
UniGeneiGga.2197

Genome annotation databases

GeneIDi373889
KEGGigga:373889

Entry informationi

Entry nameiQ8AYP8_CHICK
AccessioniPrimary (citable) accession number: Q8AYP8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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